BACKGROUND: Microbial-associated molecular patterns activate several MAP kinases, which are major regulators of the innate immune response in Arabidopsis thaliana that induce large-scale changes in gene expression. Here, we determine whether microbial-associated molecular pattern-triggered gene expression involves modifications at the chromatin level. RESULTS: Histone acetylation and deacetylation are major regulators of microbial-associated molecular pattern-triggered gene expression and implicate the histone deacetylase HD2B in the reprogramming of defence gene expression and innate immunity. The MAP kinase MPK3 directly interacts with and phosphorylates HD2B, thereby regulating the intra-nuclear compartmentalization and function of the histone deacetylase. CONCLUSIONS: By studying a number of gene loci that undergo microbial-associated molecular pattern-dependent activation or repression, our data reveal a mechanistic model for how protein kinase signaling directly impacts chromatin reprogramming in plant defense.

• MeSH
• Arabidopsis imunologie   MeSH
• chromatin fyziologie   MeSH
• flagelin imunologie   MeSH
• fosforylace MeSH
• fyziologický stres MeSH
• histondeacetylasy metabolismus   MeSH
• histony metabolismus   MeSH
• imunita rostlin * MeSH
• mitogenem aktivované proteinkinasy kinas metabolismus   MeSH
• přirozená imunita MeSH
• proteiny huseníčku metabolismus   MeSH
• restrukturace chromatinu * MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Názvy látek
• AtMPK3 protein, Arabidopsis MeSH Prohlížeč
• chromatin MeSH
• flagelin MeSH
• histondeacetylasy MeSH
• histony MeSH
• mitogenem aktivované proteinkinasy kinas MeSH
• proteiny huseníčku MeSH