The case of a 56 years old man is presented, who developed acute generalized exanthematous pustulosis 5 days after the introduction of olanzapine 10 mg. Multiple 1-mm pustules appeared on the whole body, concentrated especially on her neck and face. Within 2 days, the eruption was increasingly accompanied by erythema and pruritus. No fever, chills, nausea, vomiting, arthralgias or myalgias were recorded. The diagnosis was corroborated by hystopathology. After 7 days of treatment, olanzapine and valproate were stopped. Concomitantly, cetirizine 20 mg p.o. and methylprednisolone 500 mg i.v. were given once. During the following week betamethasone cream was applied, and the pustular eruption resolved completely.
- MeSH
- akutní nemoc MeSH
- antipsychotika škodlivé účinky MeSH
- benzodiazepiny škodlivé účinky MeSH
- exantém chemicky indukované farmakoterapie patologie MeSH
- léková dermatitida farmakoterapie etiologie patologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- olanzapin MeSH
- vezikulobulózní nemoci kůže chemicky indukované farmakoterapie patologie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- Názvy látek
- antipsychotika MeSH
- benzodiazepiny MeSH
- olanzapin MeSH
- MeSH
- exantém patologie MeSH
- houby izolace a purifikace MeSH
- kontaktní dermatitida patologie MeSH
- kůže * MeSH
- lidé MeSH
- techniky in vitro MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
