The incidence of non-albicans Candida and non-Candida species isolated from the urine of patients admitted to various departments of the Faculty Hospital of the Medical Faculty of Safárik University in Kosice was examined. From a total of 94 samples of analyzed urine 58 strains of C. albicans and 36 strains of yeasts belonging to 6 species of non-albicans Candida and non-Candida spp. were detected: C. parapsilosis (n = 23), C. tropicalis (6), C. krusei (3), C. robusta (2), C. catenulata (1) and Cryptococcus neoformans (1). In relation to the diagnosis, the yeasts were isolated from patients suffering from a kidneys disease, epididymitis, diabetes, neoplastic diseases, urogenital anomalies, obstructive uropathy, cystitis, prostatitis, hemolytic-uremic syndrome, and others.

• MeSH
• Candida classification   growth & development   isolation & purification   MeSH
• Urinary Tract Infections microbiology   MeSH
• Candidiasis complications   microbiology   MeSH
• Humans MeSH
• Infant, Newborn, Diseases MeSH
• Infant, Newborn MeSH
• Check Tag
• Humans MeSH
• Male MeSH
• Infant, Newborn MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Research Support, Non-U.S. Gov't MeSH

The proportion of Candida and non-Candida species in the clinical material from patients with respiratory-tract diseases was determined. C. albicans was isolated in 102 cases. An additional 89 strains of yeasts, isolated in association with respiratory diseases, belonged to 10 non-albicans Candida spp. and Cryptococcus spp. The prevailing species, which occurred in 47 cases, was C. parapsilosis. C. tropicalis, C. glabrata, and C. guilliermondii were isolated in 12, 10, and 9 cases, respectively. Four strains of C. krusei and three strains of C. lusitaniae and one strain each of C. freyschussii, C. robusta, C. zeylanoides, and Cryptococcus neoformans were also isolated.

• MeSH
• Candida classification   isolation & purification   MeSH
• Cryptococcus isolation & purification   MeSH
• Respiratory Tract Infections microbiology   MeSH
• Candidiasis epidemiology   microbiology   MeSH
• Humans MeSH
• Infant, Premature, Diseases epidemiology   microbiology   MeSH
• Infant, Newborn MeSH
• Sputum microbiology   MeSH
• Check Tag
• Humans MeSH
• Male MeSH
• Infant, Newborn MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Research Support, Non-U.S. Gov't MeSH

Anti-Candida antibodies were determined in a group of preterm neonates from a neonatal intensive care unit with serious diseases including candidemia. Antibodies to C. albicans blastospores, i.e. antibodies to C. albicans surface mannan and to C. albicans germ tubes were detected. Higher titers of antibodies to blastospores (1:320) occurred in all patients examined while antibodies to C. albicans germ tubes (with the highest titer of 1:160) were present in 32 out of 66 neonates examined. The highest titers of both anti-C. albicans blastospore antibodies and anti-C. albicans germ tube antibodies were detected in neonates with candidemia and disorders of saccharide metabolism.

• MeSH
• Candida albicans growth & development   immunology   isolation & purification   MeSH
• Intensive Care Units, Neonatal statistics & numerical data   MeSH
• Candidiasis blood   diagnosis   immunology   MeSH
• Humans MeSH
• Infant, Premature, Diseases epidemiology   MeSH
• Infant, Newborn MeSH
• Prevalence MeSH
• Antibodies, Fungal blood   MeSH
• Check Tag
• Humans MeSH
• Infant, Newborn MeSH
• Publication type
• Journal Article MeSH
• Names of Substances
• Antibodies, Fungal MeSH

Sixty four biopsy specimens of oral Candida leukoplakias were examined. Histological sections were stained with periodic acid-Schiff (PAS) reagent and by Grocott's silver method. C. albicans isolates were cultivated from all the patients but fungal hyphae were proved histologically only in 23 of them. PAS-positive and Grocott-positive elements were exclusively observed in the superficial epithelial layers, e.g., the cornified layer and the stratum granulosum. The inflammatory reaction was characterized by an early phase during which polymorphonuclear cells predominated. The skeletal muscle fascicles immediately adjacent to the infected epithelium showed striking degeneration and atrophy associated with a marked infiltrate of chronic inflammatory cells.

• MeSH
• Atrophy pathology   MeSH
• Staining and Labeling MeSH
• Biopsy MeSH
• Candida isolation & purification   MeSH
• Hyphae isolation & purification   MeSH
• Muscle, Skeletal pathology   MeSH
• Periodic Acid MeSH
• Middle Aged MeSH
• Humans MeSH
• Candidiasis, Oral microbiology   pathology   MeSH
• Leukoplakia, Oral microbiology   pathology   MeSH
• Aged MeSH
• Mouth Mucosa microbiology   pathology   MeSH
• Inflammation pathology   MeSH
• Check Tag
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Aged MeSH
• Publication type
• Journal Article MeSH
• Names of Substances
• Periodic Acid MeSH

One-hundred patients with candidosis of the skin, mucous membranes and nail plates (confirmed by cultivation) were examined. Topical or systemic antimycotic treatment was successful in 58 patients. After a complete evaluation, 42 patients were found to suffer from factors supporting candidosis--diabetes mellitus (12), anemia (3) and various local factors (10 patients); 27 patients showed a deficiency in cell-mediated immunity. In addition to intensive antimycotic therapy, successful treatment is affected by the actual immunity level and can be ensured by efficient immunomodulation treatment of immunodeficiency.

• MeSH
• Antifungal Agents therapeutic use   MeSH
• Candida classification   pathogenicity   MeSH
• Phagocytosis MeSH
• Antigen-Antibody Complex blood   MeSH
• Immunocompromised Host * MeSH
• Candidiasis, Cutaneous drug therapy   immunology   MeSH
• Humans MeSH
• Antibodies, Fungal blood   MeSH
• Risk Factors MeSH
• T-Lymphocytes immunology   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Journal Article MeSH
• Names of Substances
• Antifungal Agents MeSH
• Antigen-Antibody Complex MeSH
• Antibodies, Fungal MeSH