Oxidative stress plays a dual role in infections. Free radicals protect against invading microorganisms, and they can also cause tissue damage during the resulting inflammation. In the process of infection, there is generation of reactive species by myeloperoxidase, NADPH oxidase, and nitric oxide synthase. On the other hand, reactive species can be generated among others, by cytochrome P450, some metals, and xanthine oxidase. Some pathologies arising during infection can be attributed to oxidative stress and generation of reactive species in infection can even have fatal consequences. This article reviews the basic pathways in which reactive species can accumulate during infectious diseases and discusses the related health consequences.

• MeSH
• infekční nemoci imunologie   patofyziologie   MeSH
• kovy metabolismus   MeSH
• lidé MeSH
• metabolické sítě a dráhy MeSH
• NADPH-oxidasy metabolismus   MeSH
• oxidační stres * MeSH
• peroxidasa metabolismus   MeSH
• synthasa oxidu dusnatého metabolismus   MeSH
• systém (enzymů) cytochromů P-450 metabolismus   MeSH
• volné radikály imunologie   metabolismus   toxicita   MeSH
• xanthinoxidasa metabolismus   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• přehledy MeSH
• Názvy látek
• kovy MeSH
• NADPH-oxidasy MeSH
• peroxidasa MeSH
• synthasa oxidu dusnatého MeSH
• systém (enzymů) cytochromů P-450 MeSH
• volné radikály MeSH
• xanthinoxidasa MeSH