Most cited article - PubMed ID 18024365
Failure of multiple antivirals to affect high HHV-6 DNAaemia resulting from viral chromosomal integration in case of severe aplastic anaemia
Of the two human herpesvirus 6 (HHV-6) species, human herpesvirus 6B (HHV-6B) encephalitis is an important cause of morbidity and mortality after allogeneic hematopoietic stem cell transplant. Guidelines for the management of HHV-6 infections in patients with hematologic malignancies or post-transplant were prepared a decade ago but there have been no other guidelines since then despite significant advances in the understanding of HHV-6 encephalitis, its therapy, and other aspects of HHV-6 disease in this patient population. Revised guidelines prepared at the 2017 European Conference on Infections in Leukaemia covering diagnosis, preventative strategies and management of HHV-6 disease are now presented.
- MeSH
- Antiviral Agents pharmacology therapeutic use MeSH
- Hematologic Neoplasms complications diagnosis therapy MeSH
- Immunocompromised Host MeSH
- Roseolovirus Infections diagnosis etiology therapy MeSH
- Combined Modality Therapy MeSH
- Humans MeSH
- Herpesvirus 6, Human * MeSH
- Graft vs Host Disease etiology MeSH
- Practice Guidelines as Topic * MeSH
- Hematopoietic Stem Cell Transplantation adverse effects methods MeSH
- Cell Transformation, Viral MeSH
- Treatment Outcome MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Geographicals
- Europe MeSH
- Names of Substances
- Antiviral Agents MeSH