Chemical analyses of Fusarium avenaceum grown on banana medium resulted in eight novel spiroleptosphols, T1, T2 and U-Z (1-8). The structures were elucidated by a combination of high-resolution mass spectrometric data and 1- and 2-D NMR experiments. The relative stereochemistry was assigned by 1H coupling and NOESY/ROESY experiments. Absolute stereochemistry established for 7 by vibrational circular dichroism was found analogous to that of the putative polyketide spiroleptosphol from Leptosphaeria doliolum.

• Klíčová slova
• Fusarium avenaceum, PKS, polyketide synthases, polyketides, secondary metabolites, spiroleptosphol,
• MeSH
• chemické jevy MeSH
• Fusarium chemie   metabolismus   MeSH
• magnetická rezonanční spektroskopie MeSH
• metabolické sítě a dráhy MeSH
• molekulární struktura MeSH
• spirosloučeniny chemie   metabolismus   MeSH
• vysokoúčinná kapalinová chromatografie MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• spirolephtoshol MeSH Prohlížeč
• spirosloučeniny MeSH