Some endophyte isolates were isolated in a bamboo pole sample parasitized the fungus Shiraia bambusicola from Zhejiang Province. After screening through hypocrellin bacteriostatic effect and fermentation test, we got the isolate TX4 of bacterial elicitor and GZUIFR-TT1 of fungal elicitor which had certain effect to promote S. bambusicola to produce hypocrellin. The Plackett-Burman design was introduced to evaluate the effects of nine factors based on single-factor test. Yeast extract, glucose, and isolate GZUIFR-TT1 elicitor were found to be the critical activity factors for increasing the total hypocrellin production. So we identified the isolate GZUIFR-TT1 as Trametes sp. Through response surface methodology, we obtained the optimum production conditions as follows: yeast extract, 2.99 g/L; glucose, 32.45 g/L; and Trametes sp. elicitor, 81.40 μg/mL. Under the above conditions, the experimental value of hypocrellin production was 102.60 mg/L, compared with the control it increased about 7.90 times.

• MeSH
• antiinfekční látky metabolismus   MeSH
• Ascomycota metabolismus   MeSH
• biotechnologie metody   MeSH
• chinony metabolismus   MeSH
• DNA fungální chemie   genetika   MeSH
• fenol MeSH
• fermentace MeSH
• kultivační média chemie   MeSH
• mezerníky ribozomální DNA chemie   genetika   MeSH
• molekulární sekvence - údaje MeSH
• perylen analogy a deriváty   metabolismus   MeSH
• sekvenční analýza DNA MeSH
• Trametes klasifikace   genetika   růst a vývoj   izolace a purifikace   MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Názvy látek
• antiinfekční látky MeSH
• chinony MeSH
• DNA fungální MeSH
• fenol MeSH
• hypocrellin A MeSH Prohlížeč
• kultivační média MeSH
• mezerníky ribozomální DNA MeSH
• perylen MeSH