Most cited article - PubMed ID 24997586
Antibiotic treatment following a dog bite in an immunocompromized patient in order to prevent Capnocytophaga canimorsus infection: a case report
BACKGROUND: Invasive infections caused by Capnocytophaga canimorsus are rare. Immunocompromised patients, who report being bitten by or having a close contact with an animal, represent a high-risk group for this infection. There are only few dozens of infections by this bacteria manifesting as purulent meningitis reported worldwide. The reported case is a first reported case of purulent meningitis caused by by Capnocytophaga canimorsus in Czech Republic with only a limited risk factor history. CASE PRESENTATION: The patient, a 74 years old man, was referred to the infectious diseases department of a teaching hospital with clear signs of developing purulent meningitis. His anamnestic data did not show any unusual findings. He was treated for compensated diabetes mellitus type II. The blood cultures were negative and the etiological agent did not grow from the cerebrospinal fluid (CSF) on common media. Eventually, it was identified by detecting pan-bacterial DNA and DNA sequencing. Subsequently, the pathogen was confirmed by anaerobic cultivation from CSF. Only after then the patient recalled being bitten by his German shepherd puppy during play. The patient was successfully treated intravenously by ceftriaxone. CONCLUSIONS: Purulent meningitis caused by Capnocytophaga spp. is a rare disease, but it needs to be considered in patients at risk with pre-existing conditions, who report close contact with or being bitten by an animal. It is important to test for this microbe in cases with negative microbiological results for the more common agents.
- Keywords
- Capnocytophaga, Invasive infection, Purulent meningitis,
- MeSH
- Capnocytophaga genetics pathogenicity MeSH
- Ceftriaxone therapeutic use MeSH
- Gram-Negative Bacterial Infections drug therapy etiology microbiology MeSH
- Immunocompromised Host MeSH
- Bites and Stings complications MeSH
- Blood Culture MeSH
- Humans MeSH
- Meningitis, Bacterial drug therapy etiology microbiology MeSH
- Dogs MeSH
- Aged MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Dogs MeSH
- Aged MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Review MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- Ceftriaxone MeSH