The growth and conidiation of the aged Trichoderma viride culture grown in the dark, and after an induction by a light pulse, was examined in the presence of selected mono-, di(tri)saccharides, amino acids and alcohols as sole carbon sources. Hexoses and disaccharides, but not pentoses and amino acids, promoted proportionally both growth and conidiation induced by aging or light. All compounds but pentoses promoted the conidiation in aged cultures and photoconidiation in a close correlation. Ethanol, glycerol and ethylene glycol supported both growth and conidiation but these processes were not supported equally. Conidia formation with hexoses and amino acids as sole carbon sources seems to be a function of growth promotion, rather than of growth restriction (starvation, stress, aging). With glucose as sole carbon source the conidiation was not triggered by nutrient limitation, nor by the accumulation of waste metabolites. The aging-induced conidiation can be considered to be triggered by the genetic program of the microorganism rather than by its nutrient status.

• MeSH
• alkoholy MeSH
• aminokyseliny MeSH
• disacharidy MeSH
• kultivační média MeSH
• monosacharidy MeSH
• světlo * MeSH
• tma MeSH
• Trichoderma růst a vývoj   fyziologie   MeSH
• trisacharidy MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• srovnávací studie MeSH
• Názvy látek
• alkoholy MeSH
• aminokyseliny MeSH
• disacharidy MeSH
• kultivační média MeSH
• monosacharidy MeSH
• trisacharidy MeSH

Nonsteroid antiinflammatory agents (NSAIA's) (inhibitors of cyclooxygenase and lipoxygenase) of several structural series inhibited growth of Trichoderma viride. The most potent growth inhibitors were indomethacin and its derivative repanidal which inhibited in the range of 0.1 mmol/L. The weakest inhibitors were acetylsalicylic acid and lysine salicylate which exerted only a weak effect at concentrations above 1 mmol/L. The inhibition of growth was accompanied by a stimulation of conidiation in the dark. A light pulse increased the efficiency of these drugs to stimulate the conidiation. Saccharomyces cerevisiae was as sensitive to NSAIA's as T. viride while Botrytis cinerea was less sensitive. The results indicate that arachidonate metabolism may play a role in the growth of fungi and may participate also in the process of conidiation.

• MeSH
• antiflogistika nesteroidní farmakologie   MeSH
• buněčná diferenciace účinky léků   MeSH
• druhová specificita MeSH
• mitosporické houby účinky léků   fyziologie   MeSH
• Saccharomyces cerevisiae účinky léků   fyziologie   MeSH
• spory hub MeSH
• Trichoderma účinky léků   fyziologie   MeSH
• Publikační typ
• časopisecké články MeSH
• srovnávací studie MeSH
• Názvy látek
• antiflogistika nesteroidní MeSH