European grayling populations have declined significantly in their central range, prompting numerous stocking programs with reared fish that did not bring desirable population prosperity. This study evaluated the effectiveness of stocking long-reared grayling brood fish before their spawning period. It focused on monitoring the presence of juveniles coming from their natural spawn in the stream and on recapture rates and growth parameters of stocked fish to estimate their adaptability in a natural river environment. The results revealed that the recapture rate of the stocked brood fish was notably low, with significant increases only in length growth but a decreases in condition factor, suggesting poor adaptability in the wild. The limited number of young-of-year grayling from natural spawning further indicated low reproductive success. These results highlight the inadequacies of this stocking approach to strengthen the wild grayling population. We suggest alternative strategies, such as using younger stock and implementing protective measures like catch-and-release, which may improve conservation efforts and enhance the success of grayling stocking programs.

• Klíčová slova
• adaptability, brood stock, electrofishing, fishery management, spawning success,
• Publikační typ
• časopisecké články MeSH

Schizophrenia is a severe disorder characterized by positive, negative and cognitive symptoms, which are still not fully understood. The development of efficient antipsychotics requires animal models of a strong validity, therefore the aims of the article were to summarize the construct, face and predictive validity of schizophrenia models based on rodents and zebrafish, to compare the advantages and disadvantages of these models, and to propose future directions in schizophrenia modeling and indicate when it is reasonable to combine these models. The advantages of rodent models stem primarily from the high homology between rodent and human physiology, neurochemistry, brain morphology and circuitry. The advantages of zebrafish models stem in the high fecundity, fast development and transparency of the embryo. Disadvantages of both models originate in behavioral repertoires not allowing specific symptoms to be modeled, even when the models are combined. Especially modeling the verbal component of certain positive, negative and cognitive symptoms is currently impossible.

• Klíčová slova
• animal models, laboratory rodents, model validity, neurobiology, schizophrenia, schizophrenia symptoms, zebrafish,
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH