The purpose of this study was to assess the prognostic value of ultra-low dose thallium myocardial perfusion imaging. Three hundred and sixty-six patients (245 men) underwent ultra-low dose stress-redistribution imaging on CZT SPECT camera GE Discovery NM 530c. The stress test was performed by bicycle ergometry or regadenoson injection. The activity of 0.5 MBq (0.014 mCi) Tl-201 chloride per kilogram of body weight was administered. The stress images were acquired immediately and redistribution images were taken after 3 h. Patient follow-up was focused on combined end-point (death, myocardial infarction, unstable angina, revascularization and hospitalization for heart failure). Data analysis was performed from hospital database, with a mean period 23 months. Patients with revascularization within 1 month after SPECT was excluded as revascularization for diagnosis. Ischaemia on SPECT was found in 72 patients, 294 patients were without ischaemia. In patients with ischaemia there were 21 (29.2%) subjects with cardiac events, and 23 (7.9%) in patients without ischaemia (HR 4.15, 95% CI 2.30-7.51, p < 0.0001). Ultra-low dose thallium perfusion imaging using CZT camera provides very good prognostic results in assessment of myocardial ischaemia.

• Keywords
• CZT, Low-dose, Myocardial perfusion, Prognostic value, SPECT, Thallium,
• MeSH
• Time Factors MeSH
• Radiation Dosage * MeSH
• Equipment Design MeSH
• Gamma Cameras * MeSH
• Myocardial Ischemia diagnostic imaging   mortality   physiopathology   therapy   MeSH
• Tomography, Emission-Computed, Single-Photon adverse effects   instrumentation   methods   MeSH
• Cadmium * MeSH
• Coronary Circulation * MeSH
• Middle Aged MeSH
• Humans MeSH
• Pilot Projects MeSH
• Predictive Value of Tests MeSH
• Prognosis MeSH
• Disease Progression MeSH
• Purines administration & dosage   MeSH
• Pyrazoles administration & dosage   MeSH
• Radiation Exposure adverse effects   prevention & control   MeSH
• Radiopharmaceuticals administration & dosage   adverse effects   MeSH
• Thallium Radioisotopes administration & dosage   adverse effects   MeSH
• Reproducibility of Results MeSH
• Aged MeSH
• Tellurium * MeSH
• Vasodilator Agents administration & dosage   MeSH
• Exercise Test MeSH
• Zinc * MeSH
• Myocardial Perfusion Imaging adverse effects   instrumentation   methods   MeSH
• Check Tag
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Names of Substances
• CdZnTe MeSH Browser
• Cadmium * MeSH
• Purines MeSH
• Pyrazoles MeSH
• Radiopharmaceuticals MeSH
• Thallium Radioisotopes MeSH
• regadenoson MeSH Browser
• Tellurium * MeSH
• Thallium-201 MeSH Browser
• Vasodilator Agents MeSH
• Zinc * MeSH