Most cited article - PubMed ID 28374592
Prevalence protilátek proti viru hepatitidy E v České republice - sérologický přehled
[The prevalence of antibodies against Hepatitis E Virus in the Czech Republic: serological survey]
INTRODUCTION: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. METHODS: A retrospective analysis of 173 patients with HE. RESULTS: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. CONCLUSIONS: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.
- Keywords
- Czech Republic, Eastern Europe, epidemiology, hepatitis E, hepatitis E virus, therapy, viral zoonosis,
- Publication type
- Journal Article MeSH