The study aimed to contribute to understanding the role of CRP, chemerin, fetuin-A and osteopontin and to assess their suitability as biomarkers of early stages of cardiovascular diseases in psoriasis vulgaris. Serum levels measured in 28 patients and 22 controls. Patients: increased levels of CRP (p<0.001), chemerin (p<0.05), osteopontin (p<0.05) and decreased levels of fetuin-A (p<0.05), significant relationships between CRP and fetuin-A (rho=0.530, p<0.01), CRP and chemerin (rho=0.543, p<0.01), CRP and age (rho=0.590, p<0.001), osteopontin and fetuin-A (r=-0.415, p<0.05), chemerin and PASI score (rho=-0.424, p<0.05). We confirmed specific roles of the biomarkers in psoriasis. CRP, fetuin-A and osteopontin could be considered appropriate markers for the detection of early stages of cardiovascular diseases.

• MeSH
• Biomarkers MeSH
• C-Reactive Protein analysis   MeSH
• Chemokines blood   MeSH
• Adult MeSH
• alpha-2-HS-Glycoprotein analysis   MeSH
• Body Mass Index MeSH
• Middle Aged MeSH
• Humans MeSH
• Osteopontin blood   MeSH
• Psoriasis complications   MeSH
• Heart Disease Risk Factors * MeSH
• Case-Control Studies MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Names of Substances
• AHSG protein, human MeSH Browser
• Biomarkers MeSH
• C-Reactive Protein MeSH
• Chemokines MeSH
• alpha-2-HS-Glycoprotein MeSH
• Osteopontin MeSH
• RARRES2 protein, human MeSH Browser
• SPP1 protein, human MeSH Browser