Photosensitive compounds found in herbs have been reported in recent years as having a variety of interesting medicinal and biological activities. In this review, we focus on photosensitizers such as hypericin and its model compounds emodin, quinizarin, and danthron, which have antiviral, antifungal, antineoplastic, and antitumor effects. They can be utilized as potential agents in photodynamic therapy, especially in photodynamic therapy (PDT) for cancer. We aimed to give a comprehensive summary of the physical and chemical properties of these interesting molecules, emphasizing their mechanism of action in relation to their different interactions with biomacromolecules, specifically with DNA.

• Klíčová slova
• DNA, anticancer activity, danthron, emodin, hypericin, interaction, natural photosensitive compounds, quinizarin,
• MeSH
• anthraceny MeSH
• anthrachinony chemie   MeSH
• fotochemoterapie MeSH
• fotosenzibilizující látky chemie   farmakologie   MeSH
• lidé MeSH
• nádory farmakoterapie   MeSH
• perylen analogy a deriváty   chemie   farmakologie   MeSH
• protinádorové látky chemie   farmakologie   MeSH
• zvířata MeSH
• Check Tag
• lidé MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• Názvy látek
• 1,4-dihydroxyanthraquinone MeSH Prohlížeč
• anthraceny MeSH
• anthrachinony MeSH
• fotosenzibilizující látky MeSH
• hypericin MeSH Prohlížeč
• perylen MeSH
• protinádorové látky MeSH