Nejvíce citovaný článek - PubMed ID 33502550
Shape morphing technique can accurately predict pelvic bone landmarks
In silico analysis is key to understanding bone structure-function relationships in orthopedics and evolutionary biology, but its potential is limited by a lack of standardized, high-quality human bone morphology datasets. This absence hinders research reproducibility and the development of reliable computational models. To overcome this, BoneDat has been developed. It is a comprehensive database containing standardized bone morphology data from 278 clinical lumbopelvic CT scans (pelvis and lower spine). The dataset includes individuals aged 16 to 91, balanced by sex across ten age groups. BoneDat provides curated segmentation masks, normalized bone geometry (volumetric meshes), and reference morphology templates organized by sex and age. By offering standardized reference geometry and enabling shape normalization, BoneDat enhances the repeatability and credibility of computational models. It also allows for integrating other open datasets, supporting the training and benchmarking of deep learning models and accelerating their path to clinical use.
- MeSH
- databáze faktografické * MeSH
- dospělí MeSH
- kosti a kostní tkáň * anatomie a histologie diagnostické zobrazování MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- počítačová rentgenová tomografie MeSH
- počítačová simulace MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- dataset MeSH
Thanks to technical progress and the availability of virtual data, sex estimation methods as part of a biological profile are undergoing an inevitable evolution. Further reductions in subjectivity, but potentially also in measurement errors, can be brought by approaches that automate the extraction of variables. Such automatization also significantly accelerates and facilitates the specialist's work. The aim of this study is (1) to apply a previously proposed algorithm (Kuchař et al. 2021) to automatically extract 10 variables used for the DSP2 sex estimation method, and (2) to test the robustness of the new automatic approach in a current heterogeneous population. For the first aim, we used a sample of 240 3D scans of pelvic bones from the same individuals, which were measured manually for the DSP database. For the second aim a sample of 108 pelvic bones from the New Mexico Decedent Image Database was used. The results showed high agreement between automatic and manual measurements with rTEM below 5% for all dimensions except two. The accuracy of final sex estimates based on all 10 variables was excellent (error rate 0.3%). However, we observed a higher number of undetermined individuals in the Portuguese sample (25% of males) and the New Mexican sample (36.5% of females). In conclusion, the procedure for automatic dimension extraction was successfully applied both to a different type of data and to a heterogeneous population.
- Klíčová slova
- Automatic variables extraction, DSP2 method, Forensic anthropology, Sex estimation, Surface models,
- MeSH
- algoritmy * MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- pánevní kosti * diagnostické zobrazování MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- soudní antropologie * metody MeSH
- určení pohlaví podle kostry * metody MeSH
- zobrazování trojrozměrné * MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Portugalsko MeSH
A new metric for the quantitative and qualitative evaluation of bone stiffness is introduced. It is based on the spectral decomposition of stiffness matrix computed with finite element method. The here proposed metric is defined as an amplitude rescaled eigenvalues of stiffness matrix. The metric contains unique information on the principal stiffness of bone and reflects both bone shape and material properties. The metric was compared with anthropometrical measures and was tested for sex sensitivity on pelvis bone. Further, the smallest stiffness of pelvis was computed under a certain loading condition and analyzed with respect to sex and direction. The metric complements anthropometrical measures and provides a unique information about the smallest bone stiffness independent from the loading configuration and can be easily computed by state-of-the-art subject specified finite element algorithms.
- MeSH
- algoritmy MeSH
- analýza metodou konečných prvků MeSH
- biofyzika MeSH
- biomechanika * MeSH
- kosti a kostní tkáň * MeSH
- lidé MeSH
- mechanické jevy * MeSH
- spektrální analýza * metody MeSH
- teoretické modely MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH