Most cited article - PubMed ID 3490421
Antiprotozoal effects of some hydrazones
The antimicrobial action of 11 compounds involving guaiacyl- and syringyl-like structures (low-molecular-weight part of lignin), gallic acid and its derivatives, cinnamic acid and its derivatives, veratric acid, anisic acid and crotonic acid (a total of 25 compounds) against bacteria, yeast-like organisms and protozoa was examined. Aromatic compounds modified in the C-side chain and aldehydes were effective preferentially against Trichomonas vaginalis, whereas against bacteria and yeast-like organisms eugenol was the most effective inhibitor.
- MeSH
- Anti-Bacterial Agents MeSH
- Anti-Infective Agents * MeSH
- Plants, Medicinal * MeSH
- Microbial Sensitivity Tests MeSH
- Polycyclic Compounds isolation & purification pharmacology MeSH
- Pseudomonas aeruginosa drug effects MeSH
- Staphylococcus aureus drug effects MeSH
- Trichosporon drug effects MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Anti-Infective Agents * MeSH
- Polycyclic Compounds MeSH
Antibacterial, antifungal and antiprotozoal effects of nine mono- and bishydrazones of glycolaldehyde, glyoxal, methoxyacetaldehyde and glutaraldehyde were studied using eight model organisms. It was found that bishydrazones are much more efficient antimicrobial agents than monohydrazones in the case of all model microorganisms.
- MeSH
- Anti-Bacterial Agents MeSH
- Anti-Infective Agents pharmacology MeSH
- Bacillus drug effects MeSH
- Biotransformation MeSH
- Candida albicans drug effects MeSH
- Escherichia coli drug effects MeSH
- Phenylhydrazines biosynthesis metabolism MeSH
- Hydrazones metabolism pharmacology MeSH
- Micrococcus drug effects MeSH
- Pseudomonas aeruginosa drug effects MeSH
- Saccharomyces cerevisiae drug effects MeSH
- Staphylococcus aureus drug effects MeSH
- Trichomonas vaginalis drug effects MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Anti-Infective Agents MeSH
- Phenylhydrazines MeSH
- Hydrazones MeSH