The effect of bilirubin on the phagocytic activity of mouse peritoneal macrophages and on the expression of Fc receptors and receptors for SRBC was studied. Intraperitoneally administered bilirubin influenced the expression of Fc receptors for IgM, IgG2B, IgA and IgE, whereas the expression of other receptors as well as the phagocytic activity of peritoneal macrophages remained unchanged. The possible mechanism of the effect of bilirubin on Fc receptors is discussed.

• MeSH
• bilirubin farmakologie   MeSH
• fagocytóza účinky léků   MeSH
• makrofágy účinky léků   imunologie   MeSH
• myši inbrední BALB C MeSH
• myši MeSH
• receptory Fc účinky léků   MeSH
• tvorba rozet MeSH
• zvířata MeSH
• Check Tag
• myši MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• bilirubin MeSH
• receptory Fc MeSH

Fc receptors, belonging to the most important surface structures of a number of cells participating in the immune processes, have been intensely studied during the past decade. The present review summarizes the contemporary knowledge of the specificity and heterogeneity of Fc receptors and of factors influencing their expression, and includes some views on their function. In addition, it mentions their relationship to other cell surface structures, expression of Fc receptors during ontogeny of the organism and in certain diseases. Finally, data concerning the isolation and biochemical characterization of the Fc receptor molecule are presented.

• MeSH
• alergologie a imunologie MeSH
• buňky imunologie   MeSH
• chemické modely MeSH
• imunoglobuliny metabolismus   MeSH
• lidé MeSH
• metody MeSH
• molekulová hmotnost MeSH
• receptory Fc * analýza   genetika   izolace a purifikace   metabolismus   fyziologie   MeSH
• specificita protilátek MeSH
• vazebná místa protilátek MeSH
• zvířata MeSH
• Check Tag
• lidé MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• Názvy látek
• imunoglobuliny MeSH
• receptory Fc * MeSH