Most cited article - PubMed ID 38193
Partial purification and properties of glucosyltransferase from Streptomyces aureofaciens
Alizarin glucosyl transferase activity was found in five mutant strains of Streptomyces aureofaciens. The activity bears no direct relationship to the final products of tetracycline biosynthesis.
- MeSH
- Anthraquinones pharmacology MeSH
- Glucosides metabolism MeSH
- Glucosyltransferases isolation & purification metabolism MeSH
- Mutagenesis MeSH
- Streptomyces aureofaciens enzymology genetics MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- alizarin MeSH Browser
- Anthraquinones MeSH
- Glucosides MeSH
- Glucosyltransferases MeSH
Streptomyces aureofaciens glucosidizes 1,2,4-trihydroxy-9,10-anthraquinone (purpurin) added to the cultivation medium to yield the corresponding 2-beta-D-glucoside. The identity of the glucoside was demonstrated by comparing its physico-chemical properties with data of an authentic sample prepared synthetically. A further chemical glucosidation of the acetylated 2-beta-D-glucoside gives rise to 2-(hepta-O-acetyl-beta-gentiobiosyl)-4-(tetra-O-acetyl-beta-D-gluc opyranosyl) purpurin. All the derivatives are immunoactive.
- MeSH
- Anthraquinones * MeSH
- Chemical Phenomena MeSH
- Chemistry MeSH
- Fermentation MeSH
- Glucosides biosynthesis MeSH
- Mass Spectrometry MeSH
- Lectins immunology metabolism MeSH
- Magnetic Resonance Spectroscopy MeSH
- Spectrophotometry, Infrared MeSH
- Streptomyces aureofaciens metabolism MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Anthraquinones * MeSH
- Glucosides MeSH
- Lectins MeSH
- purpurin anthraquinone MeSH Browser
Substances studied at this department in 1954-1983 are reviewed; a total of 226 compounds are characterized in a tabular form. They include natural compounds as well as those prepared by biotransformation, by semisynthetic and synthetic methods.
- MeSH
- Anti-Bacterial Agents isolation & purification MeSH
- Microbiology MeSH
- Chemistry, Organic * MeSH
- Organic Chemistry Phenomena MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
