Ceska a Slovenska farmacie.
2011 Dec ;
60 (6) :
276-82.
The enzymes of cytochrome P450 3A subfamily are responsible for the metabolism of about 50% of commonly used drugs. High inter-individual variability in the activities of these enzymes has been described. The last fourth part of this review focuses on the influence of genetic polymorphism of CYP3A4 and CYP3A5 enzymes on drug effect.
- MeSH
- cytochrom P-450 CYP3A genetika metabolismus MeSH
- lidé MeSH
- polymorfismus genetický * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- CYP3A4 protein, human MeSH Prohlížeč
- CYP3A5 protein, human MeSH Prohlížeč
- cytochrom P-450 CYP3A MeSH
