INTRODUCTION: Gastric bypass has not gained as much popularity in the Czech Republic as technically simpler restrictive bariatric procedures, frequently with a fading long-term effect. The aim of the presentation is to point out the long-term results after two types of gastric bypasses. METHOD: Retrospective analysis of prospectively collected data in an initial set of patients after laparoscopic RYGB (Roux Y gastric bypass) and OAGB/MGB (one anastomosis/mini gastric bypass) performed at Breclav Hospital in 2010-2013. Evaluation based on the BAROS system, according to weight development, comorbidities, psychological aspects, complications and reoperations. RESULTS: Data available for evaluation are from 32 patients out of a total of 60; the follow-up rate is 53%. The patients are lighter by 34 kg on average (0-64 kg); TBWL (total basic weight loss): 25.7%. The majority of operated diabetics are free of signs of diabetes, and all others have a reduced need for antidiabetic medication. Hypertension, sleep apnea and psychological assessment of life in 6 domains improved. Eight of the 32 followed patients underwent reoperation during 10 years; only 2 of these procedures were acute for complications (anastomotic ulceration), both in smokers; further elective reoperations included 2 conversions of OAGB/MGB to RYGB due to reflux, 2 corrective surgeries, and 2 procedures for a suspected internal hernia. There was no conversion from laparoscopic to open surgery, no peritonitis associated with a leak, and no mortality within 30 days. The BAROS score (5.56) indicates a "very good result" of the gastric bypasses after 10 years. CONCLUSION: Gastric bypasses are safe and provide a high and lasting metabolic effect that meets the general expectations of an invasive intervention that can fundamentally improve the quality of treatment for otherwise incurable chronic diseases related to adiposity (so-called ABCD), especially type 2 diabetes.

• Klíčová slova
• bariatric surgery, diabetes surgery, gastric bypass, long-term results, metabolic surgery, type,
• MeSH
• diabetes mellitus 2. typu * chirurgie   MeSH
• gastrektomie metody   MeSH
• gastroezofageální reflux * chirurgie   MeSH
• lidé MeSH
• morbidní obezita * chirurgie   MeSH
• retrospektivní studie MeSH
• žaludeční bypass * škodlivé účinky   metody   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

Obesity has become a worldwide problem with a growing incidence, posing a risk to health, especially for cardiovascular disease, diabetes, certain types of cancer, depres-sive syndrome, and others. The methods of obesity treatment are still expanding, in addition to diet and exercise measures, pharmacological, endoscopic and surgical treatment is possible. One of the commonly performed bariatric surgical procedures is the Roux-en-Y gastric bypass, which combines restrictive and malabsorptive effects. As part of the development of new methods, the banded gastric bypass using the Fobi ring has been introduced. Its advantage is greater efficiency in reducing and maintaining -weight. One of the described complications is the migration of the Fobi ring, which can be addressed endoscopically today.

• Klíčová slova
• endoscopy, gastric bypass, obesity,
• MeSH
• lidé MeSH
• migrace cizích těles chirurgie   MeSH
• morbidní obezita chirurgie   MeSH
• žaludeční bypass * metody   škodlivé účinky   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH

INTRODUCTION: Historically, gastric bypass (GB) has been the oldest procedure used in bariatric surgery. Even though technically demanding, it had been the most widely used method for decades worldwide and still holds an irreplaceable position for its pronounced and long-term metabolic effect as well as for the therapeutic effect in gastroesophageal reflux (GERD). METHOD: The authors retrospectively analyse a series of 268 cases of GB, focusing on short-term weight loss, the metabolic effect on type two diabetes (T2DM), complication and reoperation rates and the BAROS scoring system in Roux-en-Y bypass (RYGB) and in minigastric bypass with one anastomosis (MGB/OAGB), comparing both of them to more frequently used gastric plication and sleeve gastrectomy. RESULTS: Both GB, without any increase in complication and reoperation rates, lead to a higher weight loss and the best BAROS scoring in comparison to other, simpler restrictive procedures. One year after GB, resolution of T2DM is seen in most diabetes patients operated on, the number needed to treat being.

• Klíčová slova
• bariatric and metabolic surgery, diabetes mellitus, gastric bypass, surgical treatment of diabetes, type,
• MeSH
• bariatrická chirurgie * MeSH
• gastrektomie MeSH
• lidé MeSH
• morbidní obezita * chirurgie   MeSH
• retrospektivní studie MeSH
• výsledek terapie MeSH
• žaludeční bypass * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

INTRODUCTION: Adjustable gastric banding (AGB) used to be a popular bariatric procedure. However, it fails in more than half of those operated on in the long term, becomes ineffective and must be removed. Therefore, the use of AGB has been in decline globally. Sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) are the most used bariatric revision surgeries when AGB is removed. CASE REPORT: We present the case of a woman after AGB removal and conversion to SG who developed a stenosis of the sleeve. Therefore, a decision was made to convert to RYGB with a good effect. CONCLUSION: Revisional procedures are more technically challenging than primary procedures and have higher complication rates. The most performed revisional operations include SG and RYGB. Stenosis of the sleeve can occur after SG, with a negative impact on the patient's nutritional status and quality of life. This can be managed by endoscopic dilatation, and where this solution proves ineffective, RYGB can be indicated.

• Klíčová slova
• Roux-en-Y gastric bypass, adjustable gastric banding, sleeve gastrectomy,
• MeSH
• gastrektomie metody   MeSH
• gastroplastika * škodlivé účinky   metody   MeSH
• kvalita života MeSH
• lidé MeSH
• morbidní obezita * chirurgie   MeSH
• reoperace metody   MeSH
• retrospektivní studie MeSH
• stenóza chirurgie   MeSH
• výsledek terapie MeSH
• žaludeční bypass * škodlivé účinky   metody   MeSH
• Check Tag
• lidé MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH

• MeSH
• endoskopie MeSH
• lidé MeSH
• morbidní obezita * chirurgie   MeSH
• Rouxova Y-anastomóza MeSH
• žaludeční bypass * škodlivé účinky   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

BACKGROUND: A retrospective study was undertaken to define the efficacy of both mini gastric bypass or one anastomosis gastric bypass (MGB/OAGB) and sleeve gastrectomy (SG) in type 2 diabetes mellitus (T2DM) remission in morbidly obese patients (pts). METHODS: Eight European centers were involved in this survey. T2DM was preoperatively diagnosed in 313/3252 pts (9.62%). In 175/313 patients, 55.9% underwent MGB/OAGB, while in 138/313 patients, 44.1% received SG between January 2006 and December 2014. RESULTS: Two hundred six out of 313 (63.7 %) pts reached 1 year of follow-up. The mean body mass index (BMI) for MGB/OAGB pts was 33.1 ± 6.6, and the mean BMI for SG pts was 35.9 ± 5.9 (p < 0.001). Eighty-two out of 96 (85.4%) MGB/OAGB pts vs. 67/110 (60.9%) SG pts are in remission (p < 0.001). No correlation was found in the % change vs. baseline values for hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG) in relation to BMI reduction, for both MGB/OAGB or SG (ΔFPG 0.7 and ΔHbA1c 0.4 for MGB/OAGB; ΔFPG 0.7 and ΔHbA1c 0.1 for SG). At multivariate analysis, high baseline HbA1c [odds ratio (OR) = 0.623, 95% confidence interval (CI) 0.419-0.925, p = 0.01], preoperative consumption of insulin or oral antidiabetic agents (OR = 0.256, 95% CI 0.137-0.478, p = <0.001), and T2DM duration >10 years (OR = 0.752, 95% CI 0.512-0.976, p = 0.01) were negative predictors whereas MGB/OAGB resulted as a positive predictor (OR = 3.888, 95% CI 1.654-9.143, p = 0.002) of diabetes remission. CONCLUSIONS: A significant BMI decrease and T2DM remission unrelated from weight loss were recorded for both procedures if compared to baseline values. At univariate and multivariate analyses, MGB/OAGB seems to outperform significantly SG. Four independent variables able to influence T2DM remission at 12 months have been identified.

• Klíčová slova
• Bariatric surgery, European multicenter survey, MGB/OAGB, Mini gastric bypass/one anastomosis gastric bypass, Remission, SG, Sleeve gastrectomy, T2DM, Type 2 diabetes mellitus,
• MeSH
• diabetes mellitus 2. typu komplikace   chirurgie   MeSH
• dospělí MeSH
• gastrektomie metody   MeSH
• hmotnostní úbytek MeSH
• lidé středního věku MeSH
• lidé MeSH
• morbidní obezita komplikace   chirurgie   MeSH
• následné studie MeSH
• retrospektivní studie MeSH
• výsledek terapie MeSH
• žaludeční bypass metody   MeSH
• zdravotnické přehledy MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

Bariatric surgery has been proven to be an effective method in the treatement of morbid obesity. The ideal bariatric procedure should be effective, easy to perform and safe. Sleeve gastrectomy and RYGB currently represent the most frequently used bariatric/metabolic procedures. However, they have a certain percentage of complications and post-operative morbidity and also they fail in some patients. These facts lead to the development of new surgical procedures, which also include single anastomosis sleeve ileal bypass (SASI) and single anastomosis sleeve jejunal bypass (SASJ). These procedures combines the advantages of restrictive and malabsorptive operations at the same time reducing the risk of nutrient deficiencies by maintaining passage through all the alimentary tract. The results so far are encouraging, further research and especially longer-term results are necessary.

• Klíčová slova
• SASI, SASJ, bariatric surgery, sleeve ileal bypass, sleeve jejunal bypass,
• MeSH
• anastomóza chirurgická metody   MeSH
• bariatrická chirurgie * metody   MeSH
• gastrektomie metody   MeSH
• ileum chirurgie   MeSH
• jejunum chirurgie   MeSH
• laparoskopie * MeSH
• lidé MeSH
• morbidní obezita * chirurgie   MeSH
• retrospektivní studie MeSH
• výsledek terapie MeSH
• žaludeční bypass * metody   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

• MeSH
• cholangiopankreatografie endoskopická retrográdní MeSH
• endosonografie MeSH
• laparoskopie * MeSH
• lidé MeSH
• morbidní obezita * chirurgie   MeSH
• Rouxova Y-anastomóza MeSH
• žaludeční bypass * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

PURPOSE: Obesity and its related severe comorbidities are increasing rapidly. The duodenal-jejunal bypass is an endoscopically implanted device (mimicking the Roux-en-Y gastric bypass) developed to support weight reduction and improve type 2 diabetes control. MATERIALS AND METHODS: Retrospective data analysis of consecutive patients undergoing duodenal-jejunal bypass (EndoBarrier®, DJB) implantation between 2013 and 2017 was performed to evaluate safety as well as short- and long-term efficacy. RESULTS: One hundred and twenty-one patients (mean BMI of 43.1 ± 7.2 kg/m2 and weight of 138.2 ± 28.6 kg) underwent DJB implantation. The mean dwelling time was 15.5 months, the mean total body weight loss (%TBWL) after explantation was 10.3% ± 7.9% (14.2 kg, p < 0.0001), and the mean BMI was 39.5 ± 7.3 kg/m2 (p < 0.0001). There was no significant weight gain 24 months after the explantation. Seventy-seven patients had type 2 diabetes mellitus (T2DM) with a mean HbA1c before implantation of 5.6% (n = 52). The mean HbA1c after explantation was 5.1% (p = 0.0001). Significant reductions in transaminase and lipid levels before and after explantation were observed. One complication occurred during implantation and another during explantation. In 16 patients, the device had to be extracted earlier than expected (7 for severe adverse events and 9 for adverse events; 13.2%). CONCLUSION: Despite an evident rate of adverse events, the DJB shows promise as a weight-loss procedure. Our results show that some patients implanted with the device maintained reduced weight even 24 months after explantation, while many improved T2DM control.

• Klíčová slova
• Bariatric, Duodenal-jejunal bypass, Endoscopy, Obesity, Type 2 diabetes mellitus,
• MeSH
• diabetes mellitus 2. typu * chirurgie   komplikace   MeSH
• duodenum chirurgie   MeSH
• glykovaný hemoglobin MeSH
• hmotnostní úbytek MeSH
• jejunum chirurgie   MeSH
• lidé MeSH
• morbidní obezita * chirurgie   MeSH
• obezita chirurgie   komplikace   MeSH
• retrospektivní studie MeSH
• výsledek terapie MeSH
• žaludeční bypass * metody   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• glykovaný hemoglobin MeSH

This video case report presents a patient with an invasive pancreatic mass and a history of Roux-en-Y gastric bypass surgery who underwent single-session endoscopic ultrasound-directed transgastric ERCP for tissue sampling and biliary stenting with subsequent maintenance of the newly established gastrogastrostomy. The demonstrated technique enables spectrum of endoscopic interventions in gastric bypass patients by facilitating a direct endoscopic passage through the reconnected stomach. Importantly, the method carries a risk of weight regain by essentially reversing the bypass. However, this can be an actual desire in selected cases, e.g., oncologic patients, making it a favorable choice over other alternatives.

• Klíčová slova
• EDGE, ERCP, Endoscopic ultrasound, Gastric bypass, Gastrogastrostomy, Pancreatic cancer, Roux-en-Y,
• MeSH
• cholangiopankreatografie endoskopická retrográdní MeSH
• cholestáza * MeSH
• endosonografie MeSH
• lidé MeSH
• morbidní obezita * chirurgie   MeSH
• žaludeční bypass * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH