The development of the European total hip arthroplasty in the sixties of 20th century is associated mainly with the names of G. K. McKee, J. Charnley and M. E. Muller. The SICOT meeting in Paris in 1966 introduced THA as a new method of treatment of osteoarthritis of the hip and paved the way for the commercialization of the manufacturing of prostheses. The success of this method consisted primarily in the fixation of individual components by bone cement and application of metal-to-polyethylene and metal-to-metal joints. The book presents these historical events as they have been reflected in the development of THA in the countries of the former Czechoslovakia and in the development of implants of domestic provenance. The development of THA in the former Czechoslovakia started in 1969 and was based on the Swiss school established by M. E. Muller. The Muller component with the "banana-shaped" stem was implanted using the Watson-Jones approach, the proximal femur canal was prepared by a rasp and the Palacos cement was used. This prosthesis served also as the model for the first Czech implant Poldi-Cech of I generation (the Chirulen cup available in three sizes, the "banana- shaped" femoral component with a 32 mm head-diameter and 130 degree neck-shaft angle) the development of which started in 1969 and the serial production began in 1972 in the Poldi Kladno steel company. Fatigue fractures of the "banana-shaped" stem led to the development of the concept of a femoral component with an "anatomical" stem. In Switzerland, this concept was developed by B. G. Weber. In the former Czechoslovakia the development of a new femoral component with an "anatomical" stem following the shape of the intramedullary canal with an ovoid profile and without sharp edges started in 1972. Due to the incidence of fatigue fractures of the "banana-shaped"stem and material that was not sufficiently strong (steel used for the production of osteosynthetic components), 144 degree neck-shaft angle was chosen. Reduction of the effect of bending forces on the valgus stem had eliminated fatigue fractures. This Poldi-Cech prosthesis of II generation was provided in nine sizes. The diameter of the head remained the same. Three Chirulen cups were supplemented with a "flat" cup for implantation in a dysplastic acetabulum. The prosthesis was implanted with an exact instrument set (reamer for acetabular preparation, rasp for proximal femoral preparation, alignment device for accurate positioning of both the cup and the femoral component) with the use of the Palacos cement. The production of the Poldi-Cech prosthesis of II. generation started in 1974 with the fabrication of a monoblock. Since 1986 it has been developed into a modular system (14/16 cone) with the possibility to use a ceramic head of 32 mm diameter (only in the nineties the cone size was changed to 12/14 and the heads were provided also in the 28 mm diameter). The Poldi-Cech prosthesis of II generation with the "anatomical" stem has been implanted since 1974 (i. e. during 30 years) in more than 140 000 patients in the Czech and Slovak Republics. In the same year cemented monoblock hemiarthroplasty was developed on the same basis as THA using the same "anatomical" stem and 36 to 60mm head diameter. Until now more than 35,000 of these hemiarthroplasty systems have been implanted. Until 1992 the Poldi-Cech implant was practically the only available cemented total hip replacement in the former Czechoslovakia and retrospectively it may be considered a highly successful implant. In the authors' view, the further development of THA will lead in the following years to the use of implants proved by a long-term follow-up. Preference will be given to prostheses the implantation of which will require a minimal loss of the bone stock during primary surgery and which will allow a technically easy reimplantation. The continental Europe has been recently preferring hybrid prostheses while Scandinavia witnesses an evident increase in the number of implanted cemented prostheses to the detriment of the cementless and hybrid ones. Naturally, cementless prostheses will keep dominating in young patients.

• MeSH
• dějiny 20. století MeSH
• kyčelní protézy dějiny   MeSH
• lidé MeSH
• náhrada kyčelního kloubu dějiny   MeSH
• Check Tag
• dějiny 20. století MeSH
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• historické články MeSH
• Geografické názvy
• Česká republika MeSH
• Evropa MeSH

PURPOSE OF THE STUDY: This paper was initiated to evaluate a new total hip system based on cementless fixation and focusing options for different articulations within a single hip system. MATERIAL AND METHODS: 100 patients provided with the cementless Variall hip system were evaluated clinically and radiographically. The 59 female and 41 male patients were followed for a minimum of 3 years postoperative. They were clinically evaluated using the Harris Hip Score. Radiographic analysis was based on plain x-rays at the latest follow-up evaluation. RESULTS: The evaluated patients achieved an excellent clinical result with an average Harris Hip Score of 94,3 points after an average follow-up of 42 months. The radiographic evaluation of the threaded cup did not exhibit any migration of the implant nor could we find radiolucencies. All tapered stems were radiographically stable. Due to the modified proximal design and the macrostructure an improved stem bone interface was found during the follow-up period. DISCUSSION The new cementless cup with its cylindrical threads and the spherical floor achieves an anatomic fit within the acetabulum and provides excellent primary stability. The design of the gamma inlay offers the fixation of ceramic and metal articulations without polyethylene interface. Additionally, options for conventional and cross-linked polyethylenes are available. These facts make the cup a cost-effective device. The design of the new uncemented stem guarantees a high degree of primary stability and excellent rotational stability due its rectangular cross section. This pressfit is further enhanced by the proximal macrostructure of the implant, again ensuring an excellent bond between prosthesis and bone. CONCLUSION: Thanks to the versatility of all the components this comprehensive new total hip prosthesis offers many options for a long-term successful implant. Additionally, it is a cost-effective solution - an important fact of nowadays strained financial situation in public health care.

• MeSH
• biomechanika MeSH
• dospělí MeSH
• kyčelní kloub diagnostické zobrazování   MeSH
• kyčelní protézy * MeSH
• lidé středního věku MeSH
• lidé MeSH
• náhrada kyčelního kloubu * MeSH
• následné studie MeSH
• protézy - design MeSH
• radiografie MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

PURPOSE OF THE STUDY: In the development of cementless total hip arthroplasty wear, loosening as well as stress shielding are considered as major issues. New results in literature specify survivorship of THA over 97%. Consequently the implant loosening and wear especially can be considered as almost solved. Therefore, it is essential to use bone preserving primary implants that allow for a physiological load transfer and cause no or only slight stress shielding at the proximal femur. The MAYO conservative hip stem with a wedge design ensuring immediate primary fixation of the stem with metaphyseal load transfer. MATERIAL AND METHODS: A retrospective study was performed to review the first consecutive 316 MAYO conservative hip stems implanted at the Martin-Luther-University of Halle-Wittenberg (Germany). 85.4% (270 MAYO stems) were radiographic analysed and classified according to the HHS. RESULTS: The mean HHS improved from 44.79 preoperatively to 93.58 postoperatively. 1.85% (5 MAYO stems) had to be replaced because of aseptic loosening. Furthermore the DEXA scans revealed the metaphyseal load transfer with increased bone density in the calcar region. CONCLUSION: As especially younger patients will require one or more hip revision procedures during the course of their life due to their life due to their age and activity level. These patients should receive a primary implant with proximal load transfer. Only these implants can avoid stress shielding of the proximal femur. The minimally invasive implantation of these implants can also ensure an enhanced periprosthetic bone density an optimized postoperative rehabilitation phase.

• MeSH
• kyčelní kloub diagnostické zobrazování   MeSH
• kyčelní protézy * MeSH
• lidé MeSH
• náhrada kyčelního kloubu * MeSH
• radiografie MeSH
• selhání protézy MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

PURPOSE OF THE STUDY: Several therapies are available for the treatment of deep infection in total hip arthroplasty but none is completely successful; there is no consensus on an optimal method. The aim of this study was to evaluate the treatment used in our institution and its outcomes over the last 20 years. In each method, the success of treatment was evaluated in terms of both infection control and restoration of function in the treated joint. MATERIAL: A total of 172 patients with infected total hip replacements were treated at the First Orthopedic Clinic of the First Faculty of Medicine, Charles University, Prague, between 1979 and 1998. Our sample consisted of 132 patients, 92 men and 40 women. Resection arthroplasty was performed in 62 patients. Two-stage reimplantation was used in 64 patients. Two-stage reimplantation involving skeletal traction was applied in 35 and a block spacer was used in 29 patients. The remaining patients were treated by other techniques. METHODS: The type of infection was classified according to the Coventry system. The outcome of surgery was assessed on the basis of the Tsukayma rating system, radiographic findings and the Harris hip score. RESULTS: The average follow-up time from the definitive operation was 70.8 months. In the patients who had resection arthroplasty only, the cure rate of infection was 91.9%. However, an increase in the Harris hip score, as compared with the condition before surgery, was low (9.7 points). In the patients treated by the two-stage reimplantation without a spacer but with skeletal traction, the cure rate of infection was 94.3% and the Harris score increased by 20 points. The patients who were treated by two-stage reimplantation with a spacer showed an infection cure rate of 96.5% and an increase in the Harris score by 29 points. This increase was higher by 9 points in comparison with the patients who had reimplantation without the use of a spacer. An even greater difference (28.2 points) was found when the outcomes of this technique were compared with those of resection arthroplasty. The incidence of spacer dislocation in 21% of the cases was an unexpected finding. DISCUSSION: No great differences in outcome in terms of infection cure rate were found among the methods used, i.e., two-stage reimplantation facilitated a better function for the hip joint than Girdlestone's operation. The use of a spacer in two-stage reimplantation ensured a greater comfort for the patient during treatment and gave better results in terms of joint function than treatment without a spacer. The use of a cemented spacer is an optimal method that not only ensures the stability of a limb during the period necessary for infection control but also provides conditions for the prospective implantation of a new prosthesis. The spacer also permits delivery of high-dose local antibiotics released from the cement as well as makes space for a long-term application of antibiotic-containing lavage. CONCLUSIONS: The rate of success in the treatment of an infected hip arthroplasty and the possibility of preserving the implant and thus enabling the patient to move comfortably are currently high. The prerequisite is early diagnosis and a radical surgical approach that involves the use of a method leading to the most effective eradication of infection and the maintenance of a good function for the joint. The reimplantation of a new prosthesis, after removal of the previous one and debridement of all infected tissue and material, combined with a targeted antibiotic therapy, is the method of choice for both the patient and the surgeon.

• MeSH
• dospělí MeSH
• infekce spojené s protézou chirurgie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• náhrada kyčelního kloubu * přístrojové vybavení   metody   MeSH
• reoperace MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• práce podpořená grantem MeSH
• srovnávací studie MeSH

PURPOSE OF THE STUDY: The key problem of implant fixation in THR is stress distribution, i.e. load transmission between bone and implant. The closer the load transfer is to the original physiological situation, the easier the adaptation of the periprosthetic bone to the new biomechanical conditions after implantation of the cup and the safer is its longlasting fixation. The aims of the studies were 1) to get information about the physiological load transfer in the normal hip joint, 2) to get information about the load transfer between acetabulum and acetabular sockets and vice versa, 3) to measure the periacetabular pelvic bone deformation as the stimulator of the remodelling process (third stage of osseointegration) in the normal hip joint and in hip joints fitted with different acetabular cups, 4) to study the morphological stages of osseointegration of a non-cemented press-fit cup and to compare the morphological structure of the periacetabular bone with the biomechanical data obtained by the in vitro studies and finally, 5) to compare the clinical and radiological outcome of follow-up studies of the senior author's "Press-Fit cup" with the theoretical hypotheses according to the experimental observations. MATERIAL AND METHODS: Load transfer between the acetabular bone and the femoral head on one side and press-fit cups has been determined by strain gauge measurements, finite element studies, pressure sensitive Fuji prescale films, CT-osteoabsorptiometry and telemetric measurements. Periacetabular deformation has been measured by Imetric Markers. Osseointegration of the senior author's press-fit cup and, thus, the remodelling process of the bony structures adjacent to the cup have been studied in autopsy specimens of THRs which have been in situ for several years. RESULTS: Load transfer measurements have shown that the main load in the original acetabulum as well as in the acetabulum fitted with a press-fit cup is transmitted to the periphery, especially to the acetabular cortical rim whereas the subchondral bone is exposed to lower, predominantly meridional (tension) stresses. Direct measurements of the periacetabular deformation under load revealed an increase of the peripheral press-fit with increasing stability of a (oversized) press-fit cup. Both the normal as well as the acetabulum fitted with a non-cemented cup deforms in a postero-medial direction. The histo-morphology of the periacetabular bone of autopsy specimens showed excellent bony in- and ongrowth of a porous titanium coating (SULMESH) and bone formation, especially at the periphery in zone 1 and 3 according to DeLee and Charnley. CONCLUSION: The studies have shown that the subchondral bone plate of the acetabulum has very little supportive function for non-cemented press-fit cups. For the preparation of the acetabulum it is, therefore, more important to ream the sclerotic subchondral bone until there is a well vascularized, well bleeding bone bed to facilitate osseointegration of a non-cemented acetabular socket than to preserve the subchondral bone plate as is the case in cement fixation. A non-cemented press-fit socket must transmit load predominantly to the cortical bone of the acetabular rim. Therefore, a too far medial positioning of the cup, and therefore loosing contact to the cortical rim, must be avoided under all circumstances. The clinical experience with acetabular revisions and with conversions of hip arthrodeses into a THR (where there is no subchondral bone at all) have shown the superiority of a well vascularized over a sclerotic (even mechanically stronger) bone bed. Furthermore, it has been shown that the additional use of screws for fixation of an acetabular cup is not only unnecessary but can be deleterious and causes complications including osteolysis and aseptic loosening.

• MeSH
• acetabulum patofyziologie   MeSH
• biomechanika MeSH
• hlavice femuru patofyziologie   MeSH
• kyčelní protézy * MeSH
• lidé MeSH
• náhrada kyčelního kloubu přístrojové vybavení   metody   MeSH
• osteointegrace MeSH
• protézy - design MeSH
• remodelace kosti MeSH
• senioři MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH

In our report we present the case of a 74-year-old man in whom Pseudomonas aeruginosa was identified unexpectedly in intra-operative samples taken during a one-stage revision total hip arthroplasty (THA). The patient was treated with a post-operative, eight-week antibiotic course and, subsequently, was free of infectious symptoms. However, 6 years later an infection of his THA was detected and Pseudomonas aeruginosa was again isolated. In accordance with traditional thinking this should be classified as a new infection, but some recent findings on the relationship between the host and infecting bacteria allow us to interpret this case as a recurrent infection of THA. It is speculated whether at all, or for how long, it is possible for bacteria to survive on the prosthetic surfaces without either eliciting the host's immune response or severely damaging the surrounding tissues. If it is so, prosthetic joint infection can be understood as a disturbed equilibrium between bacteria colonising the implant and the host's immune mechanisms, and thus this concept could lead to the development of new methods for prevention of this feared THA complication.

• MeSH
• infekce spojené s protézou diagnóza   mikrobiologie   MeSH
• kyčelní protézy škodlivé účinky   MeSH
• lidé MeSH
• náhrada kyčelního kloubu * MeSH
• pseudomonádové infekce diagnóza   etiologie   MeSH
• recidiva MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• kazuistiky MeSH

PURPOSE OF THE STUDY: The article presents results of surgical treatment of osteolysis around stable cementless THA. MATERIAL AND METHODS: The authors evaluated 18 operated on cases of osteolysis around stable THA of ABG 1 type with a minimal follow-up of 4 years (49-70 months). The group included 6 men and 12 women who were at the time of revision 47 years old (36-56, SD 6.52). The average period between the primary and revision surgery was 45 months (23-66, SD 13.84), the average size of the original cup was 49.6 mm (44-54, SD 3.03), the median thickness of polyethylene was 7.5 mm (4.9-8.9). The average HHS prior to reoperation was 68.5 points (10-98, SD 18.3) and only three hips were completely asymptomatic (3/18, 17%). Polyethylene inlay was replaced twice, both acetabular components in twelve cases, the acetabular and femoral components in four cases. In 16 cases radical debridement and treatment of defects by bone grafting was an important part of surgery. OUTCOMES: By the time of the latest check, in total three revision surgeries were performed (3/18, 17%). Neither of them was necessitated by loosening of the revision cup or use of bone grafts. Revised were both hips after the replacement of polyethylene cup inlay. Stable bone fixation and healing of bone defect was achieved in 15 hips in which the implant replacement was combined with bone grafting (15/16, 94%). The revision cup was on average by 3.16 mm bigger than the original cup (p = 0.001). The average HHS during the latest check was 79 points (p = 0.056). DISCUSSION: In osteolysis around a stable implant, many North-American authors prefer the replacement of polyethylene cup inlay in case of an undamaged well-oriented metal cup with a functional lock. By contrast, the authors of this study in such indication replace the whole acetabular component. This discrepancy may be explained by the ABG 1 THA which often triggers an extensive osteolysis and fails relatively soon. CONCLUSION: Despite a small number of cases the study has proved that the bone bed damaged by osteolysis is able to accommodate a new cementless implant. A necessary part of the surgery is radical debridement and in more extensive defects also bone grafting.

• MeSH
• cementování MeSH
• dospělí MeSH
• kyčelní protézy škodlivé účinky   MeSH
• lidé středního věku MeSH
• lidé MeSH
• náhrada kyčelního kloubu škodlivé účinky   MeSH
• osteolýza diagnóza   etiologie   chirurgie   MeSH
• polyethylen MeSH
• reoperace MeSH
• transplantace kostí MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• Názvy látek
• polyethylen MeSH

BACKGROUND AND AIMS: At present, revision surgery of a total hip replacement is a major problem that must be dealt with by all orthopedic facilities. Aseptic loosening of the acetabular component is often associated with destruction of the original spherical shape of the acetabulum and the formation of bone defects. An orthopedist faces the challenge of acetabular revision and stable fixation of the new acetabular component in an effort to re-establish the functioning of the hip replacement. MATERIAL AND METHODS: The authors evaluated a group of 74 patients in whom they implanted an oblong revision cup due to aseptic loosening of the acetabular component from August 2000 until December 2003. The mean duration of the follow-up period was 63 months (ranging from 38 to 78 months). RESULTS AND CONCLUSIONS: The authors reported very good results from the use of this implant, where osteointegration and good functional outcome evaluated according to the Harris Hip Score (HHS) were achieved in 95% of cases. The long-term outcome should be the subject of further investigation.

• MeSH
• artróza kyčelních kloubů chirurgie   MeSH
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• náhrada kyčelního kloubu škodlivé účinky   MeSH
• následné studie MeSH
• nekróza hlavice femuru diagnostické zobrazování   etiologie   chirurgie   MeSH
• protézy - design MeSH
• protézy a implantáty * MeSH
• radiografie MeSH
• reoperace přístrojové vybavení   MeSH
• retrospektivní studie MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• výsledek terapie MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• srovnávací studie MeSH

PURPOSE OF THE STUDY: Arthroscopic examination of joints has recently gained wide application. Due to hip joint shape and a difficult approach to it, hip arthroscopy has long remained outside the attention and abilities of arthroscopists. The authors present their first experience with operative hip arthroscopy that offers new options for the treatment of intra-articular pathology of the hip joint. MATERIAL: In the years 2001-2003, 24 hip arthroscopies were performed. The following pathological conditions were diagnosed and treated: loose bodies, chondral lesions of the femoral head and acetabulum, ruptures of the labrum acetabuli and ligamentum teres, impingement syndrome of the labrum acetabuli, and coxitis. No post-operative neurologic symptoms or vascular complications were observed. METHODS: All procedures were carried out on patients in a supine position, with the treated joint in traction. A standard 30 degrees device and common instruments for arthroscopic surgery were used. The instruments were inserted in the articular fissure with the use of an X-ray intensifier. Movement in the hip joint during surgery is very limited due to traction, joint shape and the length of working canals. After traction is released, it is possible to examine also the intra-articular part of the femoral neck. RESULTS: The pre-operative complaints (clunking, painful joint) were relieved up to 4 to 6 weeks after surgery in 23 patients. In one patient primarily diagnosed with coxitis, infection was not eradicated after lavage and debridement and, because inflammation deeply affected the femoral head, the hip was eventually treated by Girdlestone arthroplasty. The results were evaluated clinically and on the basis of the Merle d'Aubigne and Postel questionnaire assessing pain and walking abilities by both the patients and the surgeon. All 24 patients reported poor or average conditions before surgery and, after surgery, 23 experienced improvement to a very good or average condition. One patient's state failed to improve and was evaluated as poor both before and after surgery. DISCUSSION: Hip arthroscopy is a minimal invasive technique which allows us to diagnose and, at the same time, treat intra-articular pathology in a gentle manner. In arthroscopic surgery, correct diagnosis (X-ray, CT and MRI), correct patient's position, their body mass (obesity), selection of appropriate approaches to the joint, surgeon's experience and potentials of arthroscopic instruments all play an important role. We assume that, with increasing experience, the number of patients as well as the scope of diagnosed and treated pathological conditions of the hip joint will grow. The outcomes of operative arthroscopy were very good (improvement in 23 of 24 patients) and it is probable that this technique can slow down or prevent early wear-and-tear hip arthritis. CONCLUSIONS: In our country, operative arthroscopy of the hip is only at its beginning. However, it can be assumed that, similarly to other large joints, it will soon become a widely used, indispensable diagnostic and therapeutic method.

• MeSH
• artroskopie * metody   MeSH
• kyčelní kloub chirurgie   MeSH
• lidé MeSH
• nemoci kloubů diagnóza   chirurgie   MeSH
• pooperační komplikace MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH

PURPOSE OF THE STUDY: The orthopaedic community has unanimously adopted the view that ultra high molecular weight polyethylene (UHMWPE) wear particles are a very frequent cause of aseptic implant loosening. Some studies have tried to provide objective evidence for this.We have found descriptions of particle distribution or morphology, but no report that would objectively cor- relate the number of particles in zones surrounding an implant with the extent of damage to these zones. The aim of this study was to develop a method allowing us to evaluate a number of samples with polyethylene abrasive wear large enough to find association between the extent of damage around a THA and the number of biologically active UHMWPE wear particles, 0.1 to 10 microm in size. MATERIAL AND METHODS: In 28 patients undergoing revision total hip arthroplasty (THA) at the 1st Orthopaedic Clinic, 1st Faculty of Medicine, Char- les University, we took samples of typical osteoaggressive granuloma from defined zones around the implant; the zones corresponded to those described by Gruen and DeLee. The extent of tissue damage in each zone was evaluated on the basis of pre-operative radiographs and by the extent of osteolysis and damage to soft tissues actually observed during revision THA. The volume of wear particles in each zone was assessed by the IRc method developed by us; this is based on a quantitative evaluation of infrared spectra. To verify the methodology, a comparison between tissue damage and the number of particles in each zone was made in three randomly selected patients. RESULTS: We introduced a method of detailed orthopaedic evaluation which enabled us to categorize zones around a revised THA according to the extent of damaged tissue. As a result, a series of zones ranked by the extent of damaged tissue, or an "orthopaedist's statement" (OS), was obtained. At the same time we adopted a method, based on infrared spectroscopy and termed IRc, by which the number of particles in the samples of damaged tissues and osteoaggressive granulomas collected from the area around a revised THA was determined.The results of evaluation were presented as numerical data that, in a defined way, were converted into a series of zones ranked according to the number of wear particles, i.e., the "result of measurement" (RM). In this study we verified the methods described above and made a comparison of OSs and RMs for three randomly selected patients. The very good agreement found confirmed the reliability of both methods which will soon be used to evaluate a group of patients large enough to provide statistically significant results. DISCUSSION: The IRc method determines a total volume of UHMWPE wear particles, 0.1 to 10 microm in size, which are generally considered to be most biologically active. This study suggests that the distribution of particles around a THA is uneven and that relation between tissue damage and the number of wear particles in individual zones surrounding a THA does exist. The major conclusion from the orthopaedic point of view is a confirmation of the assumption that UHMWPE wear particles are one of the chief causes of THA failure. Although this fact is generally accepted, studies correlating the number of particles with tissue damage and osteolysis in individual zones are very scarce. CONCLUSIONS: The quick and simple IRc method offers a possibility to quantify polyethylene wear particles in soft tissues. The number of 0.1 to 10 microm wear polyethylene particles correlated with pre-operative radiographic findings and orthopaedic evaluation of revision THAs in three randomly selected patients. The confirmed correlation between the extent of tissue damage in individual zones surrounding a THA and the volume of wear particles detected in these zones supports the view that UHMWPE wear particles are one of the main causes of THA failure.

• MeSH
• kyčelní kloub patologie   MeSH
• kyčelní protézy škodlivé účinky   MeSH
• lidé MeSH
• mikroskopie elektronová rastrovací MeSH
• náhrada kyčelního kloubu škodlivé účinky   MeSH
• polyethyleny * MeSH
• reoperace MeSH
• selhání protézy * MeSH
• spektrofotometrie infračervená MeSH
• spektrometrie rentgenová emisní MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• Názvy látek
• polyethyleny * MeSH
• ultra-high molecular weight polyethylene MeSH Prohlížeč