AIM: To compare the degree of posterior capsule opacification (PCO) after AquaLase and NeoSoniX phacoemulsification methods during an 8-year follow-up period using two types of software. DESIGN: Prospective, randomized clinical trial. METHODS: AquaLase was used in the right eye and NeoSoniX in the left eye of each patient with bilateral cataract. RESULTS: Fifty patients were analyzed 1 year, 46 patients 3 years, and 37 patients 8 years after cataract surgery. Mean EPCO 2000 values were for the AquaLase group 0.324 ± 0.305 and for the NeoSoniX group 0.298 ± 0.341 (P = 0.53) 1 year after surgery, for the AquaLase group 0.582 ± 0.506 and for the NeoSoniX group 0.594 ± 0.515 (P = 0.87) 3 years after surgery, and for the AquaLase group 0.648 ± 0.567 and for the NeoSoniX group 0.673 ± 0.542 (P = 0.30) 8 years after surgery. The OSCA results were for the AquaLase group 0.7097 ± 0.3778 and for the NeoSoniX group 0.8584 ± 0.4323 (P = 0.046) 1 year after surgery, for the AquaLase group 0.9667 ± 0.736 and for the NeoSoniX group 0.9540 ± 0.5250 (P = 0.91) 3 years after surgery, and for the AquaLase group 1,035 ± 0,952 and for the NeoSoniX group 1,103 ± 0,741 (P = 0.44) 8 years after surgery. CONCLUSION: There was minimal PCO difference between these 2 approaches, AquaLase and NeoSoniX. Neither AquaLase nor NeoSoniX technique was able to prevent a natural progression of PCO.

• Klíčová slova
• AquaLase, NeoSoniX, posterior capsule opacification,
• MeSH
• časové faktory MeSH
• fakoemulzifikace škodlivé účinky   metody   MeSH
• lidé MeSH
• následné studie MeSH
• pooperační komplikace etiologie   MeSH
• prospektivní studie MeSH
• zkalení zadního pouzdra čočky etiologie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• randomizované kontrolované studie MeSH
• srovnávací studie MeSH

PURPOSE: To compare the extent of posterior capsule opacification (PCO) after AquaLase and NeoSoniX phacoemulsification methods using two types of software for PCO quantification. DESIGN: Prospective, randomized clinical trial. METHODS: At the Department of Ophthalmology, University Hospital in Hradec Králové, 50 patients (100 eyes) were analyzed one year after surgery. AquaLase was used in the right eye and NeoSoniX in the left eye of each patient. One year after surgery, digital retroillumination photographs of anterior segments were obtained. The Evaluation of Posterior Capsule Opacification (EPCO) 2000 software (Berlin, Germany) and the Open-Access Systematic Capsule Assessment (OSCA) system (Edinburgh, United Kingdom) were used for PCO assessment. Best-corrected Snellen visual acuity (BCVA) was evaluated before and after surgery. Statistical analysis was performed using parametric tests. RESULTS: The EPCO 2000 results were as follows: mean value for right eyes, 0.324+/-0.305; mean value for left eyes, 0.298+/-0.341; no difference was proved (P=.532). The OSCA results were as follows: for right eyes, 0.7097+/-0.3777; for left eyes, 0.8584+/-0.4323; significant difference (P=.046), worse for left eyes. No correlation between EPCO 2000 and OSCA results was established (P>.001; correlation coefficient, 0.347). BCVA for the right eyes was 0.837+/-0.262 and for the left eyes was 0.849+/-0.224. Neodymium:yytrium-aluminum-garnet capsulotomy was performed in one eye in the NeoSoniX group, and in no eyes in the AquaLase group. CONCLUSIONS: There was no significant difference in PCO measured by EPCO 2000, however, PCO after AquaLase as assessed by EPCO 2000 was slightly denser. The OSCA system gave significantly higher scores in the NeoSoniX group. No correlation between EPCO 2000 and OSCA outcomes was proved.

• MeSH
• dospělí MeSH
• fakoemulzifikace metody   MeSH
• implantace nitrooční čočky MeSH
• katarakta etiologie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• pooperační komplikace * MeSH
• pouzdro oční čočky patologie   MeSH
• přední segment oční patologie   MeSH
• prospektivní studie MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• software MeSH
• zraková ostrost MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• randomizované kontrolované studie MeSH
• srovnávací studie MeSH

PURPOSE: To prospectively compare the degree of posterior capsule opacification (PCO) after AquaLase and NeoSoniX phacoemulsification methods during the 3-year follow-up period. DESIGN: Prospective, randomized clinical trial. METHODS: Setting at the Department of Ophthalmology, University Hospital in Hradec Králové. Patients with bilateral cataract were included. AquaLase was used in the right eye and NeoSoniX in the left eye of each patient. The AcrySof SA60AT intraocular lens (Alcon Laboratories, Fort Worth, Texas, USA) was implanted in all eyes. The Evaluation of Posterior Capsule Opacification (EPCO) 2000 software (Developed by Tetz MR and associates, Berlin, Germany) and the Open-Access Systematic Capsule Assessment (OSCA) system (Devised by Aslam TM, Edinburgh, United Kingdom) were used for PCO assessment 1, 2, and 3 years after cataract surgery. RESULTS: Fifty patients were analyzed 1 year, 47 patients 2 years, and 46 patients 3 years after cataract surgery. Mean EPCO 2000 values were for the AquaLase group 0.324 +/- 0.305 and for the NeoSoniX group 0.298 +/- 0.341 (P = .53) 1 year after surgery, for the AquaLase group 0.429 +/- 0.322 and for the NeoSoniX group 0.478 +/- 0.337 (P = .30) 2 years after surgery, and for the AquaLase group 0.582 +/- 0.506 and for the NeoSoniX group 0.594 +/- 0.515 (P = .87) 3 years after surgery. The OSCA results were for the AquaLase group 0.7097 +/- 0.3778 and for the NeoSoniX group 0.8584 +/- 0.4323 (P = .046) 1 year after surgery, for the AquaLase group 0.7515 +/- 0.4555 and for the NeoSoniX group 0.8103 +/- 0.4498 (P = .44) 2 years after surgery, and for the AquaLase group 0.9667 +/- 0.736 and for the NeoSoniX group 0.9540 +/- 0.5250 (P = .91) 3 years after surgery. Neodymium-yttrium-aluminun-garnet capsulotomy rate for AquaLase vs NeoSoniX was 0:1 eyes 1 year, 1:3 eyes 2 years, and 1:4 eyes 3 years after surgery. No significant difference between those 2 groups was established, except the OSCA outcomes 1 year postoperatively. CONCLUSION: There was only minimal PCO difference between these 2 approaches, AquaLase and NeoSoniX. Neither AquaLase nor NeoSoniX technique was able to prevent a natural progression of PCO.

• MeSH
• fakoemulzifikace přístrojové vybavení   metody   MeSH
• implantace nitrooční čočky MeSH
• katarakta etiologie   patofyziologie   terapie   MeSH
• laserová terapie MeSH
• lasery pevnolátkové MeSH
• lidé MeSH
• následné studie MeSH
• pooperační komplikace * MeSH
• pouzdro oční čočky patologie   chirurgie   MeSH
• progrese nemoci MeSH
• prospektivní studie MeSH
• zraková ostrost MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• randomizované kontrolované studie MeSH
• srovnávací studie MeSH

PURPOSE: To evaluate irrigation/aspiration and posterior capsulectomy in the treatment of the posterior capsule opacification (PCO). SETTING: Department of Ophthalmology, School of Medicine, Comenius University, Bratislava, Slovakia. MATERIAL AND METHODS: Between 1.1.1999 and 31.7.2000 we treated 75 patients (79 eyes) for PCO. Cataract surgery was performed in the years 1990-1999. The artificial intraocular lens (IOL) was implanted in 62 eyes. The interval between cataract surgery and PCO surgery ranged from 4 m.-10 y. The regenerative type of PCO was present in 41, fibrotic in 23 and combined in 15 eyes. Irrigation/aspiration (I/A) was performed in 44 eyes. Capsulectomy with a vitrectomy probe was performed in 35 eyes. I/A procedure was 42x performed with a bimanual system. Capsulectomy was performed in combinations of various insertions of the infusion line (without, anterior chamber maintainer-AChM, pars plana) and capsulectomy (limbal or pars plana approach). It was evaluated: occurrence of peri- and postoperative complications; achieved best corrected visual acuity. RESULTS: Complications during I/A: posterior capsule tearing with vitreous prolaps 4x, IOL subluxation 3x, partial zonular dialysis 2x-1x with vitreous prolaps. During capsulectomy performed through the limbus was observed vitreous prolaps in two eyes. After capsulectomy, performed through pars plana without infusion line, was observed the chronical corneal oedema in one eye. The best corrected visual acuity improved for 2 and more lines in 79.5% of eyes after I/A procedure and in 74.3% of eyes after capsulectomy. The achieved visual acuity lower then 6/60 was caused by changes not related to the cataract and PCO surgery. After testing of various combinations, the most suitable capsulectomy procedure seems to be: infusion line through the limbus, capsulectomy through the radial scleral tunnel incision. In this fashion it is possible to perform the procedure as no-stitch surgery. CONCLUSIONS: Instead of possibility of occurrence of various peri- and postoperative complication after I/A and capsulectomy used for treatment of PCO these procedures complete possibilities in the treatment of PCO. For the regenerative type of PCO is suitable I/A procedure. For the fibrotic type of PCO is suitable capsulectomy through pars plana with AChM. By this procedure it is possible to remove also nearly all vitreous opacities.

• MeSH
• dospělí MeSH
• extrakce katarakty škodlivé účinky   MeSH
• katarakta etiologie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• pouzdro oční čočky chirurgie   MeSH
• recidiva MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH

AIM: The aim of the retrospective study was to establish the frequency of the posterior lens capsule opacification after the cataract surgery and artificial intraocular lens (IOL) Acri.Smart 46S (Acri.Tech Zeiss) implantation. MATERIAL AND METHODS: The study group consisted of 72 eyes (30 men and 28 women), their average age was 65.4 +/- 8.4 years, with performed cataract surgery and implanted IOL Acri.Smart 46S (Acri.Tech Zeiss). After the average period of 32.4 +/- 7.3 months after the surgery, the patients underwent the examination with refractive error measurement, uncorrected and best-corrected visual acuity for for, and posterior lens capsule transparency examination with dilated pupils and with retroillumination photography taken by NIDEK EAS-100 device. RESULTS: After the average follow-up period of 32.4 +/- 7.3 months after the surgery, the refractive error was -0.32 +/- 0.8 diopters and average cylindrical error -0.8 +/- 0.6 Dcyl. The uncorrected visual acuity (UCVA) was 0.72 +/- 0.3, and the best-corrected visual acuity (BCVA) 0.95 +/- 0.2. The average diameter of the examined posterior capsule was 5.89 +/- 2.1 mm, and the transparency of the posterior capsule was 98.41 +/- 8.5%. In two eyes (2.7%) only, the YAG capsulotomy was performed. CONCLUSION: The IOL Acri.Smart is safe, easy to implant IOL, which meets the requirements of the microincision surgery. The IOL had very low incidence of posterior lens capsule opacification, and in two eyes (2.7%) only the YAG capsulotomy was performed.

• MeSH
• extrakce katarakty škodlivé účinky   MeSH
• implantace nitrooční čočky škodlivé účinky   MeSH
• lidé středního věku MeSH
• lidé MeSH
• nitrooční čočky škodlivé účinky   MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• zkalení zadního pouzdra čočky etiologie   MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH

PURPOSE: To report late postoperative opacification of a hydrophobic acrylic intraocular lens (IOL) AcryNovaTMPC 610Y as well as the clinical consequences in patients 10 years after uncomplicated cataract surgery. MATERIALS AND METHODS: Medical records were reviewed of 23 patients (26 eyes) with AcryNovaTMPC 610Y implantated between years 2005 and 2007. Next clinical examination was performed 10 years after surgery. We assessed best corrected distance visual acuity (BCDVA), contrast sensitivity (CSV-1000E) and relative opacity of IOL material, (OCULUS Pentacam HR). Results of BCDVA and Pentacam were analysed statistically. One explanted IOL was analysed using anterior segment OCT in vitro and spectroscopic method EDX (Energy-dispersive X-ray spectroscopy). RESULTS: Opacification led to a statistically significant reduction in the best corrected distance visual acuity (BCDVA) = (0,95 ± 0,10) versus (0,87 ± 0,20) and to increase of IOL opacity only in some lenses but statistically significant in the average (6,37 ± 2,16)% versus value of (14,22 ± 5,87)%. In the explanted IOL we have documented structural changes of primarily hydrophobic raw material leading to property of hydrophilic one. CONCLUSION: Some batches of AcryNovaTMPC 610Y were produced from raw material of poor quality which is the cause of its structural changes and its progressive opacification.

• Klíčová slova
• Pentacam, hydrophobic intraocular lens, intraocular lens AcryNovaTMPC 610Y, material opacification, posterior capsule opacification,
• MeSH
• extrakce katarakty MeSH
• implantace nitrooční čočky * MeSH
• lidé MeSH
• nitrooční čočky * MeSH
• pooperační komplikace * MeSH
• prospektivní studie MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

PURPOSE: To compare posterior capsule opacification (PCO) incidence and the best corrected visual acuity (BCVA) in patients who had the soft intraocular lens (IOL) made of hydrophobic acrylic material (AcrySof MA30BA, MA60BM) implanted in their one eye and IOL made of silicone material (Allergan SI-30NB) implanted in their second eye. All patients included in this study were operated on at Department of Ophthalmology, University Hospital, Hradec Králové, Czech Republic during the period from 1999 to 2002. METHODS: Twenty-four patients (8 males, 21 females) were included in this study; they were 3 to 6 years after surgery (median 5 years). The EPCO 2000 software (The Evaluation of Posterior Capsule Opacification) was used for PCO assessment. Eyes treated with Nd: YAG laser capsulotomy were excluded from EPCO 2000 evaluation. The density of the opacification was graded clinically from 1 to 4. We compared BCVA, PCO index for every PCO grade and total PCO index. RESULTS: Seven eyes of five patients required Nd: YAG laser capsulotomy, 2 eyes with AcrySof IOL, 5 eyes with Allergan IOL. Median of total PCO index for 48 eyes of 24 patients was for AcrySof IOL 0.496 vs. 0.315 for Allergan IOL. On the evaluation, median of BCVA was for AcrySof IOL 1.0 vs. 0.67 for Allergan IOL. CONCLUSIONS: The difference in PCO incidence and BCVA between the silicone and the soft acrylic IOLs were not conclusive in this study. But Nd: YAG laser capsulotomy incidence was higher in the silicone IOLs.

• MeSH
• akrylové pryskyřice MeSH
• dospělí MeSH
• extrakce katarakty MeSH
• implantace nitrooční čočky * MeSH
• katarakta patologie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• nitrooční čočky škodlivé účinky   MeSH
• pouzdro oční čočky patologie   MeSH
• recidiva MeSH
• senioři MeSH
• silikonové elastomery MeSH
• zraková ostrost MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• srovnávací studie MeSH
• Názvy látek
• akrylové pryskyřice MeSH
• silikonové elastomery MeSH

In a group of 1700 patients after operation of cataract with implantation of IOL the authors found opacification of the posterior capsule in 765 instances (45%). Treatment was provided with a Nd-YAG laser using a picosecond regime. The authors discuss the causes of opacification, successful surgery and its complications.

• MeSH
• extrakce katarakty * MeSH
• katarakta etiologie   patologie   MeSH
• laserová terapie * MeSH
• lidé středního věku MeSH
• lidé MeSH
• nitrooční čočky * MeSH
• pouzdro oční čočky patologie   MeSH
• recidiva MeSH
• senioři MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• senioři MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH

PURPOSE: To evaluate and compare posterior capsule opacification (PCO) incidence and the best-corrected visual acuity (BCVA) in patients who underwent the implantation of intraocular lens (IOL) made of polymethylmethacrylate (PMMA), or hydrophobic acrylic material, or silicone material. All patients were examined 7 years after the surgery at the Department of Ophthalmology, University Hospital, Hradec Králové, Czech Republic, E.U. METHODS: In this 60 study, sixty eyes (44 patients) were evaluated; 20 eyes with IOLs made of PMMA with round edge, 20 eyes with IOLs made of hydrophobic acrylic material with square edge and 20 eyes with IOLs made of silicone material with round edge. They were examined 7 years after surgery. The eyes treated with Nd:YAG laser capsulotomy were excluded from the EPCO 2000 evaluation. The EPCO 2000 software (Evaluation of Posterior Capsule Opacification) was used for PCO assessment. The density of the opacification was graded clinically from 1 to 4. The BCVA, the PCO index for every PCO grade and total PCO index were compared. RESULTS: Mean of total PCO index for PMMA IOLs was 0.451 +/- 0.619; for hydrophobic acrylic IOLs 0.361 +/- 0.397; and for silicone IOLs 0.552 +/- 0.372. During the examination, we have found the BCVA mean to be for PMMA IOLs 0.79 +/- 0.26, for hydrophobic acrylic IOLs 0.87 +/- 0.19, and silicone IOLs 0.78 +/- 0.29 respectively. Twenty eyes of twenty patients required Nd:YAG laser capsulotomy: twelve eyes with PMMA IOLs, two eyes with hydrophobic acrylic IOLs, and six eyes with silicone IOLs. CONCLUSIONS: In this study, the difference in PCO incidence and BCVA among PMMA, hydrophobic acrylic, and silicone IOLs were not statistically significant. The highest incidence of the Nd:YAG laser capsulotomy was in the group of PMMA IOLs, then in silicone IOLs, and the lowest incidence was in the group of hydrophobic acrylic IOLs.

• MeSH
• akryláty MeSH
• extrakce katarakty * MeSH
• implantace nitrooční čočky * MeSH
• katarakta etiologie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• nitrooční čočky * MeSH
• polymethylmethakrylát MeSH
• recidiva MeSH
• senioři MeSH
• silikony MeSH
• zraková ostrost MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• Názvy látek
• akryláty MeSH
• polymethylmethakrylát MeSH
• silikony MeSH

PURPOSE: To compare the degree of posterior capsule opacification (PCO) after cataract surgery in patients with type 2 diabetes mellitus (DM) and in nondiabetic patients. PATIENTS AND METHODS: All surgeries were done at Department of Ophthalmology, University Hospital in Hradec Králové and three-piece Alcon AcrySof intraocular lens (MA60BM or MA30BA) was implanted in all eyes. Seven years after surgery, examination of eyes was done including best corrected Snellen visual acuity (BCVA) measurement. Digital retroillumination photographs of mydriatic anterior segments were taken and PCO was assessed using EPCO 2000 software for PCO quantification. Patients enrolled in the study were devided into two groups--with type 2 DM and without DM. EPCO index for 4 PCO severity grades and Total EPCO index for entire IOL were compared between the groups. The incidence of Nd:YAG laser capsulotomy and operative Elschnigg pearls removal, as well as BCVA, were also evaluated. Statistical analysis was performed using nonparametric tests. RESULTS: 82 patients (140 eyes) were analyzed. 26 of them (36 eyes) were type 2 diabetics (DM group), none type 1 diabetics, remaining 56 nondiabetic patients (104 eyes) were enrolled in the control group. Total EPCO index for the DM group was 0.531 +/- 0.543, for the control group 0.492 +/- 0.532, no significant difference (P = 0.66). No significant different in Nd:YAG capsulotomy rate (22.2% for DM vs. 17.3% for control, P = 0.62) and operative Elschnigg pearls removal (8.3% for DM vs. 1.9% for control, P = 0.11) was proved. BCVA in the DM group was 0.80 +/- 0.29, in the control group 0.82 +/- 0.22, no significant difference (P = 0.78). CONCLUSION: No significant difference in PCO extent, Nd:YAG capsulotomy rate and operative PCO treatment was proved between the patients with type 2 DM and the control group. However, all outcomes were nonsignificantly worse in the diabetic patients.

• MeSH
• diabetes mellitus 2. typu komplikace   MeSH
• extrakce katarakty * škodlivé účinky   MeSH
• implantace nitrooční čočky * MeSH
• katarakta komplikace   MeSH
• lidé středního věku MeSH
• lidé MeSH
• recidiva MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• klinické zkoušky kontrolované MeSH