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Léčba pyoderma gangrenosum adalimumabem
[Adalimumab treatment for pyoderma gangrenosum]
Michael P. Hefferman, Milan J. Anadkat, David I. Smith
Jazyk čeština Země Česko
- MeSH
- antiflogistika terapeutické užití MeSH
- lidé MeSH
- monoklonální protilátky terapeutické užití MeSH
- pyoderma gangrenosum farmakoterapie MeSH
- Check Tag
- lidé MeSH
A 47-year-old woman was referred to Washington University dermatology clinic for a nonhealing ulcer on her right shin of 8 months' duration. She reported having had a similar ulcer on her left shin 6 years ago. The patient's medical history was significant for non–insulin-dependent diabetes mellitus, hypertension, and osteoarthritis. On examination, she was found to have a 2 x 3-cm punched-out ulcer with rolled borders on her right shin. Evaluation of a biopsy specimen taken 6 months prior to presentation showed extensive dermal necrosis with ulceration and abscess formation and microangiopathy manifested by thickening of the capillary walls with fibrinous deposits and microthrombi. The overall histologic findings were thought to be most consistent with atrophie blanche.
Adalimumab treatment for pyoderma gangrenosum
Lit.: 22
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- AR
- 040 __
- $a ABA008 $b cze $c ABA008 $d ABA008 $e AACR2
- 041 0_
- $a cze $b eng
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- $a xr
- 100 1_
- $a Hefferman, Michael P.
- 245 10
- $a Léčba pyoderma gangrenosum adalimumabem / $c Michael P. Hefferman, Milan J. Anadkat, David I. Smith
- 246 11
- $a Adalimumab treatment for pyoderma gangrenosum
- 314 __
- $a Divisions of Dermatology, Wright State University School of Medicine, Dayton
- 504 __
- $a Lit.: 22
- 520 9_
- $a A 47-year-old woman was referred to Washington University dermatology clinic for a nonhealing ulcer on her right shin of 8 months' duration. She reported having had a similar ulcer on her left shin 6 years ago. The patient's medical history was significant for non–insulin-dependent diabetes mellitus, hypertension, and osteoarthritis. On examination, she was found to have a 2 x 3-cm punched-out ulcer with rolled borders on her right shin. Evaluation of a biopsy specimen taken 6 months prior to presentation showed extensive dermal necrosis with ulceration and abscess formation and microangiopathy manifested by thickening of the capillary walls with fibrinous deposits and microthrombi. The overall histologic findings were thought to be most consistent with atrophie blanche.
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a pyoderma gangrenosum $x farmakoterapie $7 D017511
- 650 _2
- $a antiflogistika $x terapeutické užití $7 D000893
- 650 _2
- $a monoklonální protilátky $x terapeutické užití $7 D000911
- 700 1_
- $a Anadkat, Milan J. $7 gn_A_00005799
- 700 1_
- $a Smith, David I.
- 773 0_
- $w MED00013433 $t Archives of dermatology $g Roč. 7, č. 3 (2007), s. 164-166 $x 1214-8466
- 910 __
- $a ABA008 $b B 2212 $c 113 $y 1
- 990 __
- $a 20080708145843 $b ABA008
- 991 __
- $a 20080709135558 $b ABA008
- 999 __
- $a ok $b bmc $g 622026 $s 474459
- BAS __
- $a 3
- BMC __
- $a 2007 $b 7 $c 3 $d 164-166 $i 1214-8466 $m Archives of dermatology (české a slovenské vydání) $x MED00013433
- LZP __
- $a 2008-8/mkas
