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Ethylene glycol poisoning in the Czech Republic (2000-2002)

Krenová M, Pelclová D, Navrátil T, Merta M, Tesar V

. 2006 ; 24 (2) : 180-184.

Jazyk angličtina Země Švýcarsko

Perzistentní odkaz   https://www.medvik.cz/link/bmc07520403
E-zdroje Online

NLK Karger Journals od 1983 do 2009

cz BACKGROUND: The objective of the study was to evaluate the severity of kidney damage retrospectively and to analyze prognostic factors following ethylene glycol (EG) poisonings. METHODS: Data concerning the clinical course of patients with EG poisoning between 2000 and 2002 were analyzed. The chi2 test, Student's t test, Fisher's test and the calculation of linear correlation coefficients were used for statistical analysis. RESULTS: Thirty-three discharge records were obtained. Three patients died, and 11 patients developed acute renal failure (mean maximum serum creatinine level 618 micromol/l). Upon discharge, serum creatinine levels were still elevated in 10 patients. In all but 1 patient, renal function completely normalized within 20 months after intoxication. CONCLUSION: Adult men are the most endangered segment of the population. The most important prognostic factors are the ingested dose and early antidotal treatment. EG toxic kidney damage is reversible.

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