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Serotonin-depleted rats are capable of learning in active place avoidance, a spatial task requiring cognitive coordination
Tomáš Petrásek, Aleš Stuchlík
Jazyk angličtina Země Česko
NLK
Directory of Open Access Journals
od 1991
Free Medical Journals
od 1998
ProQuest Central
od 2005-01-01
Medline Complete (EBSCOhost)
od 2006-01-01
Nursing & Allied Health Database (ProQuest)
od 2005-01-01
Health & Medicine (ProQuest)
od 2005-01-01
ROAD: Directory of Open Access Scholarly Resources
od 1998
- MeSH
- antagonisté serotoninu farmakologie MeSH
- fenklonin MeSH
- financování organizované MeSH
- kognice fyziologie účinky léků MeSH
- krysa rodu rattus MeSH
- pohybová aktivita fyziologie účinky léků MeSH
- potkani Long-Evans MeSH
- serotonin metabolismus MeSH
- učení vyhýbat se fyziologie účinky léků MeSH
- vnímání prostoru fyziologie účinky léků MeSH
- zvířata MeSH
- Check Tag
- krysa rodu rattus MeSH
- mužské pohlaví MeSH
- zvířata MeSH
Neurotransmitter substrate of spatial cognition belongs to current topics in behavioral neuroscience. The present study examined the effects of serotonin depletion with p-chlorophenylalanine on learning of rats in active place avoidance, a spatial task requiring allothetic mapping and cognitive coordination and highly dependent upon hippocampus. Serotonin depletion transiently increased locomotor activity in response to footshocks, but it did not change the avoidance efficiency measured by three spatial parameters. These results suggest that serotonin neurotransmission is not crucial for cognitive coordination and allothetic learning, i.e. the processes, which are crucial for active place avoidance performance.
Citace poskytuje Crossref.org
Lit.: 20
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