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Deproteinized bovine bone versus beta-tricalcium phosphate in sinus augmentation surgery: a comparative histologic and histomorphometric study
A Simunek, D Kopecka, RV Somanathan, S Pilathadka, T Brazda
Jazyk angličtina Země Spojené státy americké
Typ dokumentu srovnávací studie, klinické zkoušky kontrolované
Grantová podpora
NK7711
MZ0
CEP - Centrální evidence projektů
Digitální knihovna NLK
Plný text - Část
Zdroj
- MeSH
- dospělí MeSH
- financování organizované MeSH
- fosforečnany vápenaté MeSH
- kostní náhrady MeSH
- lidé středního věku MeSH
- lidé MeSH
- minerály MeSH
- průřezové studie MeSH
- regenerace kostí MeSH
- senioři MeSH
- sinus maxillaris chirurgie MeSH
- skot MeSH
- stomatochirurgické předprotetické výkony metody MeSH
- transplantace kostí MeSH
- zvířata MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- skot MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- klinické zkoušky kontrolované MeSH
- srovnávací studie MeSH
PURPOSE: To compare the efficacy of 2 common materials in sinus augmentation surgery and to assess their contribution when enriched with autogenous bone. MATERIALS AND METHODS: The prospective human study was performed in 48 sinus grafting operations using beta-tricalcium phosphate or deproteinized bovine bone (pure or mixed with 10% to 20% autogenous bone) or autogenous bone. Biopsy specimens were taken after 9 months. Statistical evaluation was done with a 2-sample t test (P < .05). RESULTS: When autogenous bone was used, 49.2% +/- 3.1% of new bone was found, which is significantly higher than in all the other groups. A higher proportion (34.2% +/- 13.1%) of the new vital bone was found in the deproteinized bovine bone group, in comparison with the beta-tricalcium phosphate group (21.4% +/- 8.1%) and the beta-tricalcium phosphate composite graft group (24.0% +/- 6.6%; P < .05). No significant differences between single-component grafts and corresponding composite grafts were established. CONCLUSIONS: Sinus augmentation with the aforementioned augmentation materials is a well-accepted procedure. However, autogenous bone alone was the best material. More new bone was found using deproteinized bovine bone than beta-tricalcium phosphate. The addition of 10% to 20% autogenous bone to the bone substitute did not significantly influence the new bone formation.
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- $a Šimůnek, Antonín, $d 1953- $7 nlk19990074122
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- $a Deproteinized bovine bone versus beta-tricalcium phosphate in sinus augmentation surgery: a comparative histologic and histomorphometric study / $c A Simunek, D Kopecka, RV Somanathan, S Pilathadka, T Brazda
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- $a Department of Dentistry, Charles University in Prague, Faculty of Medicine, Hradec Kralove, Czech Republic. simunek@email.cz
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- $a PURPOSE: To compare the efficacy of 2 common materials in sinus augmentation surgery and to assess their contribution when enriched with autogenous bone. MATERIALS AND METHODS: The prospective human study was performed in 48 sinus grafting operations using beta-tricalcium phosphate or deproteinized bovine bone (pure or mixed with 10% to 20% autogenous bone) or autogenous bone. Biopsy specimens were taken after 9 months. Statistical evaluation was done with a 2-sample t test (P < .05). RESULTS: When autogenous bone was used, 49.2% +/- 3.1% of new bone was found, which is significantly higher than in all the other groups. A higher proportion (34.2% +/- 13.1%) of the new vital bone was found in the deproteinized bovine bone group, in comparison with the beta-tricalcium phosphate group (21.4% +/- 8.1%) and the beta-tricalcium phosphate composite graft group (24.0% +/- 6.6%; P < .05). No significant differences between single-component grafts and corresponding composite grafts were established. CONCLUSIONS: Sinus augmentation with the aforementioned augmentation materials is a well-accepted procedure. However, autogenous bone alone was the best material. More new bone was found using deproteinized bovine bone than beta-tricalcium phosphate. The addition of 10% to 20% autogenous bone to the bone substitute did not significantly influence the new bone formation.
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