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Nucleolar transplantation in oocytes and zygotes: challenges for further research
H Fulka, J Jr Fulka
Jazyk angličtina Země Velká Británie
Typ dokumentu práce podpořená grantem, přehledy
NLK
Free Medical Journals
od 1996 do Před 1 rokem
Open Access Digital Library
od 1996-01-01
Medline Complete (EBSCOhost)
od 1995-01-01 do Před 1 rokem
- MeSH
- asistovaná reprodukce MeSH
- buněčné jadérko transplantace MeSH
- embryo savčí cytologie MeSH
- lidé MeSH
- oocyty cytologie MeSH
- zvířata MeSH
- zygota cytologie MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- práce podpořená grantem MeSH
- přehledy MeSH
In germinal vesicles of immature mammalian oocytes, including humans, as well as in pronuclei in 1-cell stage embryos, prominent nuclear organelles, nucleoli, can be easily detected even under a relatively low magnification. In humans, it has been clearly documented that their number, position and distribution in pronuclei can be used as an indicator of embryonic developmental potential. In the light of some recent experiments showing the feasibility of nucleolar manipulation we discuss here if these new approaches can be used to rescue those embryos with abnormal pronuclear nucleolar patterns.
Literatura.
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