Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Comparison of imaging methods in POEMS syndrome

Jiri Minarik, Vlastimil Scudla, Jaroslav Bacovsky, Tomas Pika, Filip Ctvrtlik, Iva Metelkova, Miroslav Myslivecek

. 2012 ; 156 (1) : 52-57.

Language English Country Czech Republic

Document type Case Reports, Comparative Study, Research Support, Non-U.S. Gov't

POEMS syndrome is a clinical condition with a very heterogeneous clinical manifestation. Its presentation as well as monitoring is complex and dependent on the clinician´s experience. One of the leading presenting symptoms is based on evaluation of skeletal damage with typical osteosclerotic or mixed lesions. Aims and methods. Our aim was to compare the usefulness of different imaging methods in the diagnostics of POEMS syndrome, such as conventional radiography, densitometry, technetium scintigraphy, PET/CT scan, MRI and angiography on a series of three patients with POEMS syndrome with different clinical manifestations and course of disease. Results. Our series demonstrates different types of skeletal involvement in POEMS syndrome. Although conventional X-ray is the imaging method mostly used for the evaluation, its sensitivity and specificity is low. Under specific conditions, other imaging methods should be considered, giving a more complex outlook of the disease’s skeletal involvement. Nevertheless, FDG-PET/CT confirmed its superiority in defining both skeletal lesions as well as the activity of the neoplastic process. Conclusions. We conclude that the different manifestation of the disease implies the necessity of a complex evaluation of imaging methods in mutual concordance. FDG-PET/CT emerges as the most contributive method for the evaluation of both the extent and activity of the disease.

Obsahuje 1 tabulku

Bibliography, etc.

Literatura

000      
00000naa a2200000 a 4500
001      
bmc12020728
003      
CZ-PrNML
005      
20121112124749.0
007      
ta
008      
120725s2012 xr f f 000 0eng||
009      
AR
040    __
$a ABA008 $d ABA008 $e AACR2 $b cze
041    0_
$a eng
044    __
$a xr
100    1_
$a Minařík, Jiří $7 xx0106330 $u Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, University Hospital Olomouc
245    10
$a Comparison of imaging methods in POEMS syndrome / $c Jiri Minarik, Vlastimil Scudla, Jaroslav Bacovsky, Tomas Pika, Filip Ctvrtlik, Iva Metelkova, Miroslav Myslivecek
500    __
$a Obsahuje 1 tabulku
504    __
$a Literatura $b 18
520    9_
$a POEMS syndrome is a clinical condition with a very heterogeneous clinical manifestation. Its presentation as well as monitoring is complex and dependent on the clinician´s experience. One of the leading presenting symptoms is based on evaluation of skeletal damage with typical osteosclerotic or mixed lesions. Aims and methods. Our aim was to compare the usefulness of different imaging methods in the diagnostics of POEMS syndrome, such as conventional radiography, densitometry, technetium scintigraphy, PET/CT scan, MRI and angiography on a series of three patients with POEMS syndrome with different clinical manifestations and course of disease. Results. Our series demonstrates different types of skeletal involvement in POEMS syndrome. Although conventional X-ray is the imaging method mostly used for the evaluation, its sensitivity and specificity is low. Under specific conditions, other imaging methods should be considered, giving a more complex outlook of the disease’s skeletal involvement. Nevertheless, FDG-PET/CT confirmed its superiority in defining both skeletal lesions as well as the activity of the neoplastic process. Conclusions. We conclude that the different manifestation of the disease implies the necessity of a complex evaluation of imaging methods in mutual concordance. FDG-PET/CT emerges as the most contributive method for the evaluation of both the extent and activity of the disease.
650    02
$a dospělí $7 D000328
650    02
$a senioři nad 80 let $7 D000369
650    02
$a kosti a kostní tkáň $x patologie $x radiografie $x radioizotopová diagnostika $7 D001842
650    02
$a ženské pohlaví $7 D005260
650    02
$a lidé $7 D006801
650    02
$a magnetická rezonanční tomografie $7 D008279
650    02
$a mužské pohlaví $7 D008297
650    02
$a osteoskleróza $x diagnóza $x komplikace $x radiografie $x radioizotopová diagnostika $7 D010026
650    02
$a POEMS syndrom $x diagnóza $x komplikace $7 D016878
650    02
$a počítačová rentgenová tomografie $7 D014057
650    _2
$a multimodální zobrazování $7 D064847
655    _2
$a kazuistiky $7 D002363
655    _2
$a srovnávací studie $7 D003160
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Ščudla, Vlastimil, $d 1946- $7 jn20000402953 $u Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, University Hospital Olomouc
700    1_
$a Bačovský, Jaroslav $7 xx0053311 $u Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, University Hospital Olomouc
700    1_
$a Pika, Tomáš $7 xx0071238 $u Department of Internal Medicine III – Nephrology, Rheumatology and Endocrinology, University Hospital Olomouc
700    1_
$a Čtvrtlík, Filip $7 jx20081030067 $u Department of Radiology, University Hospital Olomouc
700    1_
$a Metelková, Iva $7 xx0104819 $u Department of Nuclear Medicine, University Hospital Olomouc
700    1_
$a Mysliveček, Miroslav, $d 1946- $7 jn20000401824 $u Department of Nuclear Medicine, University Hospital Olomouc
773    0_
$t Biomedical papers $x 1213-8118 $g Roč. 156, č. 1 (2012), s. 52-57 $w MED00012606
856    41
$u http://biomed.papers.upol.cz/pdfs/bio/2012/01/08.pdf $y plný text volně přístupný
910    __
$a ABA008 $b A 1502 $c 958 $y 2
990    __
$a 20120725124231 $b ABA008
991    __
$a 20121112124803 $b ABA008
999    __
$a ok $b bmc $g 914909 $s 778004
BAS    __
$a 3
BMC    __
$a 2012 $b 156 $c 1 $d 52-57 $i 1213-8118 $m Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic $n Biomed. Pap. Fac. Med. Palacký Univ. Olomouc Czech Repub. (Print) $x MED00012606
LZP    __
$a 2012-13/mkme

Find record

Citation metrics

Loading data ...

Archiving options

Loading data ...