• Something wrong with this record ?

Urgent termination of pregnancy in pre-eclampsia and panel of antiphospholipid antibodies

L. Hradecky, I. Subrt, Z. Ulcova-Gallova

. 2009 ; 62 (6) : 412-417.

Language English Country Denmark

Document type Journal Article, Research Support, Non-U.S. Gov't

Persistent link   https://www.medvik.cz/link/bmc12025481

Grant support
NR8917 MZ0 CEP Register

PROBLEM: The present work was undertaken to investigate the occurence of autoantibodies to eight various phospholipids in time of urgent termination of the pregnancy (sectio caesarea) in patients in reproductive age with severe preeclamptic symptoms. METHOD OF STUDY: Autoantibodies against annexin V, ph-serine, ph-ethanolamine, ph-inositol, ph-DL-glycerol, cardiolipin, beta2-glycoprotein I (beta2-GPI), and phosphatidic acid were studied by ELISA methods. RESULTS: Increased levels of IgA-beta2-glycoprotein I, IgG-beta2-glycoprotein I, IgG- anti-ph-serine, and IgG-anticardiolipin were found in sera of preeclamptic women in the time of urgent sectio caesarea when compared to the control group with physiological pregnancy. CONCLUSION: Supposed increase in various antiphospholipid antibodies (aPLs) levels due to the stress during the short time of admission and a need for a quick medical decision to terminate the pregnancy was not unambiguously proven, but our results are evidently influenced by the current urgent life-saving treatment.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc12025481
003      
CZ-PrNML
005      
20140219095819.0
007      
ta
008      
120816s2009 dk f 000 0#eng||
009      
AR
024    7_
$a 10.1111/j.1600-0897.2009.00759.x $2 doi
035    __
$a (PubMed)19895376
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a dk
100    1_
$a Hradecký, Libor, $d 1965- $7 xx0104673 $u Department of Gynecology and Obstetrics, Charles University and Faculty Hospital, Pilsen, Czech Republic.
245    10
$a Urgent termination of pregnancy in pre-eclampsia and panel of antiphospholipid antibodies / $c L. Hradecky, I. Subrt, Z. Ulcova-Gallova
520    9_
$a PROBLEM: The present work was undertaken to investigate the occurence of autoantibodies to eight various phospholipids in time of urgent termination of the pregnancy (sectio caesarea) in patients in reproductive age with severe preeclamptic symptoms. METHOD OF STUDY: Autoantibodies against annexin V, ph-serine, ph-ethanolamine, ph-inositol, ph-DL-glycerol, cardiolipin, beta2-glycoprotein I (beta2-GPI), and phosphatidic acid were studied by ELISA methods. RESULTS: Increased levels of IgA-beta2-glycoprotein I, IgG-beta2-glycoprotein I, IgG- anti-ph-serine, and IgG-anticardiolipin were found in sera of preeclamptic women in the time of urgent sectio caesarea when compared to the control group with physiological pregnancy. CONCLUSION: Supposed increase in various antiphospholipid antibodies (aPLs) levels due to the stress during the short time of admission and a need for a quick medical decision to terminate the pregnancy was not unambiguously proven, but our results are evidently influenced by the current urgent life-saving treatment.
650    _2
$a potrat léčebný $7 D000032
650    _2
$a dospělí $7 D000328
650    _2
$a antifosfolipidové protilátky $x krev $7 D017152
650    _2
$a ELISA $7 D004797
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a fosfoserin $x imunologie $7 D010768
650    _2
$a placentární oběh $x imunologie $7 D021041
650    _2
$a preeklampsie $x krev $x imunologie $x patofyziologie $x terapie $7 D011225
650    _2
$a těhotenství $7 D011247
650    _2
$a trombóza $7 D013927
650    _2
$a beta-2-glykoprotein I $x imunologie $7 D053482
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Šubrt, Ivan, $d 1960- $7 xx0106759
700    1_
$a Ulčová-Gallová, Zdenka, $d 1954- $7 jn20000402453
773    0_
$w MED00000296 $t American journal of reproductive immunology (New York, N.Y. : 1989) $x 1600-0897 $g Roč. 62, č. 6 (2009), s. 412-417
856    41
$u https://pubmed.ncbi.nlm.nih.gov/19895376 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y m $z 0
990    __
$a 20120816 $b ABA008
991    __
$a 20140219100626 $b ABA008
999    __
$a ok $b bmc $g 947523 $s 782827
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2009 $b 62 $c 6 $d 412-417 $i 1600-0897 $m American journal of reproductive immunology $n Am J Reprod Immunol $x MED00000296
GRA    __
$a NR8917 $p MZ0
LZP    __
$a Pubmed-20120816/10/02

Find record

Citation metrics

Archiving options