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The effect of hydrolysis degree on the properties of antibacterial polymeric films based on poly(vinyl alcohol) and zinc sulphate for biomedical applications
V. Sedlarik, T. Galya, J. Sedlarikova, P. Valasek, P. Saha,
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- antibakteriální látky chemie farmakologie MeSH
- diferenciální skenovací kalorimetrie MeSH
- Escherichia coli účinky léků MeSH
- hydrolýza MeSH
- polymery chemie farmakologie MeSH
- polyvinylalkohol chemie MeSH
- Pseudomonas aeruginosa účinky léků MeSH
- síran zinečnatý chemie MeSH
- spektroskopie infračervená s Fourierovou transformací MeSH
- Staphylococcus aureus účinky léků MeSH
- teoretické modely MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Fully and partially hydrolyzed poly(vinyl alcohol) (PVA) was modified with zinc sulphate in the concentration range from 0 to 9 wt% of recalculated zinc content using the solvent cast technique. The resulting polymeric films were characterized by optical microscopy, stress-strain analysis, differential scanning calorimetry and Fourier transform infrared spectroscopy (FT-IR-ATR). In addition, agar diffusion test and dilution and spread plate technique were used for determination of antibacterial properties of the films against both Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae) bacterial strains. A mathematical model was applied on the measured data and parameters characterizing the antibacterial efficiency of the material were calculated and discussed. The results revealed that the PVA hydrolysis degree can play an important role in all studied properties, including antibacterial activity of the all PVA-based materials.
Citace poskytuje Crossref.org
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- $a Sedlařík, Vladimír $u Polymer Centre, Faculty of Technology, Tomas Bata University in Zlin, 76272 Zlin, Czech Republic. sedlarik@ft.utb.cz
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- $a Fully and partially hydrolyzed poly(vinyl alcohol) (PVA) was modified with zinc sulphate in the concentration range from 0 to 9 wt% of recalculated zinc content using the solvent cast technique. The resulting polymeric films were characterized by optical microscopy, stress-strain analysis, differential scanning calorimetry and Fourier transform infrared spectroscopy (FT-IR-ATR). In addition, agar diffusion test and dilution and spread plate technique were used for determination of antibacterial properties of the films against both Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae) bacterial strains. A mathematical model was applied on the measured data and parameters characterizing the antibacterial efficiency of the material were calculated and discussed. The results revealed that the PVA hydrolysis degree can play an important role in all studied properties, including antibacterial activity of the all PVA-based materials.
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