Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Changes of immunological profiles in patients with chronic myeloid leukemia in the course of treatment

Zuzana Humlová, Hana Klamová, Ivana Janatková, Karin Malícková, Petra Králíková, Ivan Šterzl, Zdenek Roth, Eva Hamšíková, Vladimír Vonka

. 2010 ; 2010 () : 137320. [pub] 20101212

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc12027161

Grantová podpora
NS10634 MZ0 CEP - Centrální evidence projektů

In the previous paper of ours we compared, prior to start any treatment, a number of immunological parameters in 24 chronic myeloid leukemia patients with the same number of healthy subjects matched by age and sex. We found significant differences in the levels of immunoglobulins, the C4 component of complement, the C-reactive protein, interleukin 6, the composition of lymphocyte population and the production of some cytokines by stimulated CD3+ cells. Eleven of these patients were followed longitudinally. After treatment with hydroxyurea, interferon alpha, imatinib mesylate and dasatinib, or various combinations thereof, hematological remission was achieved in all patients and complete cytogenetic remission in nine of them. There was a nearly general tendency towards normalization of the abnormalities observed in the patients at their enrollment.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc12027161
003      
CZ-PrNML
005      
20160405164619.0
007      
ta
008      
120816s2010 enk f 000 0#eng||
009      
AR
024    7_
$a 10.1155/2010/137320 $2 doi
035    __
$a (PubMed)21197073
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Humlová, Zuzana, $u Department of Immunology and Microbiology, 1st Medical Faculty, Charles University, General Teaching Hospital in Prague, Prague, Czech Republic; Department of Clinical Biochemistry and Laboratory Medicine, 1st Medical Faculty, Charles University, Prague, Czech Republic. zuzana.humlova@seznam.cz $d 1973- $7 xx0014342
245    10
$a Changes of immunological profiles in patients with chronic myeloid leukemia in the course of treatment / $c Zuzana Humlová, Hana Klamová, Ivana Janatková, Karin Malícková, Petra Králíková, Ivan Šterzl, Zdenek Roth, Eva Hamšíková, Vladimír Vonka
520    9_
$a In the previous paper of ours we compared, prior to start any treatment, a number of immunological parameters in 24 chronic myeloid leukemia patients with the same number of healthy subjects matched by age and sex. We found significant differences in the levels of immunoglobulins, the C4 component of complement, the C-reactive protein, interleukin 6, the composition of lymphocyte population and the production of some cytokines by stimulated CD3+ cells. Eleven of these patients were followed longitudinally. After treatment with hydroxyurea, interferon alpha, imatinib mesylate and dasatinib, or various combinations thereof, hematological remission was achieved in all patients and complete cytogenetic remission in nine of them. There was a nearly general tendency towards normalization of the abnormalities observed in the patients at their enrollment.
650    _2
$a dospělí $7 D000328
650    _2
$a protinádorové látky $x terapeutické užití $7 D000970
650    _2
$a C-reaktivní protein $x analýza $7 D002097
650    _2
$a komplement $x analýza $7 D003165
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a hydroxymočovina $x terapeutické užití $7 D006918
650    _2
$a přirozená imunita $7 D007113
650    _2
$a imunoglobuliny $x krev $7 D007136
650    _2
$a imunologické faktory $x terapeutické užití $7 D007155
650    _2
$a interferon alfa $x terapeutické užití $7 D016898
650    _2
$a interleukin-6 $x krev $7 D015850
650    _2
$a chronická myeloidní leukemie $x imunologie $x terapie $7 D015464
650    _2
$a longitudinální studie $7 D008137
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé středního věku $7 D008875
650    _2
$a piperaziny $x terapeutické užití $7 D010879
650    _2
$a inhibitory proteinkinas $x terapeutické užití $7 D047428
650    _2
$a pyrimidiny $x terapeutické užití $7 D011743
650    _2
$a T-lymfocyty $x metabolismus $7 D013601
650    _2
$a thiazoly $x terapeutické užití $7 D013844
650    _2
$a výsledek terapie $7 D016896
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Klamová, Hana $u Clinical Department, Institute of Hematology and Blood Transfusion, Prague, Czech Republic $7 xx0081721
700    1_
$a Janatková, Ivana, $u Department of Clinical Biochemistry and Laboratory Medicine, 1st Medical Faculty, Charles University, Prague, Czech Republic $d 1946- $7 xx0102916
700    1_
$a Černá, Karin $u Department of Clinical Biochemistry and Laboratory Medicine, 1st Medical Faculty, Charles University, Prague, Czech Republic $7 xx0096040
700    1_
$a Králíková, Petra, $u Department of Immunology, 2nd Medical Faculty, Charles University, Prague, Czech Republic $d 1979- $7 xx0110555
700    1_
$a Šterzl, Ivan, $u Department of Immunology and Microbiology, 1st Medical Faculty, Charles University, General Teaching Hospital in Prague, Prague, Czech Republic $d 1954- $7 jn20000402887
700    1_
$a Roth, Zdeněk, $u Department of Biostatistics, National Institute of Health, Prague, Czech Republic $d 1930-2015 $7 xx0110852
700    1_
$a Hamšíková, Eva $u Department of Experimental Virology, Institute of Hematology and Blood Transfusion, Prague, Czech Republic $7 xx0052821
700    1_
$a Vonka, Vladimír, $u Department of Experimental Virology, Institute of Hematology and Blood Transfusion, Prague, Czech Republic $d 1930- $7 jk01150642
773    0_
$w MED00013777 $t Clinical & developmental immunology $x 1740-2530 $g Roč. 2010(2010), s. 137320
856    41
$u https://pubmed.ncbi.nlm.nih.gov/21197073 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y m $z 0
990    __
$a 20120816 $b ABA008
991    __
$a 20160405164341 $b ABA008
999    __
$a ok $b bmc $g 949203 $s 784507
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2010 $b 2010 $d 137320 $e 20101212 $i 1740-2530 $m Clinical & developmental immunology $n Clin Dev Immunol $x MED00013777
GRA    __
$a NS10634 $p MZ0
LZP    __
$b NLK112 $a Pubmed-20120816/11/02

Najít záznam

Citační ukazatele

Možnosti archivace