Objective: To develop Logical Observation Identifeers Names and Codes (LOINC) codes to represent constitutional cytogenetic test results for electronically exchanging coded and structured result reports. The LOINC codes developed must be feexible and sustainable for easy maintenance. The goal is to create a standard set of codes that are feexible enough to be used for all unique conventional and molecular cytogenetic results. Design: Patient de-identifeed sample result reports were obtained from ARUP Laboratories for a variety of normal and abnormal constitutional studies using G-banding, FISH and array-CGH. Information models were created to capture the semantic relationships of the key data elements that existed in the reports. Sample reports were subsequently obtained from Emory and Mayo Clinic Cytogenetics Laboratories to verify the information models. The information models were then used to guide the systematic creation of the LOINC codes. Results: A post-coordinated approach was used in developing the LOINC codes for cytogenetics test results. LOINC panel codes were created to represent the hierarchical structures implied by the reports. A master panel was created to contain three LOINC subpanels; each of the three subpanels held the structure for chromosome analysis results that uses a difeerent technique. Conclusion: The LOINC codes we created met our objective and will allow the use of well established health informatics standards to exchange coded and structured cytogenetic test results between testing laboratories and ordering institutions. Use of standard structures and terminologies for cytogenetic results is critical for efeective communication between testing laboratories and clinicians. This minimizes misinterpretation, leads to consistency, and provides the EHR systems feexibility of customizing formatting to present more clinician-friendly reports.

Departments of Pediatrics Human Genetics and Pathology University of Utah and Cytogenetics and Molecular Cytogenetics ARUP Laboratories Salt Lake City Utah

Dept of Biomedical Informatics University of Utah Salt Lake City Utah

Intermountain Healthcare Salt Lake City Utah

Lantana Consulting Group LLC East Thetford Vermont

Lister Hill National Center for Biomedical Communications National Library of Medicine Bethesda Maryland

Development of loinc for integrating constitutional cytogenetic test result reports into electronic health records [elektronický zdroj] /

References provided by Crossref.org

Obsahuje 8 tabulek

Literatura