The paper studies immunologic features of speleotherapy in patients during the restorative period. One hundred and twenty-eight patients suffering from chronic obstructive pulmonary disease (COPD) at the stage of an incomplete remission were examined. The patient groups of 74 men and 54 women were divided into 2 representative groups by a method of randomization. Studies showed a pronounced reliable positive dynamics in indices of cellular and humoral links of immune status in patients with COPD after speleotherapy: an increase in concentrations of subpopulations in all the studying of lymphocytes; normalization in correlation between subpopulations СД4 and СД8 lymphocytes; decrease of ABL level to tissual antigen of the lungs; an increase in PhA, a number of В-lymphocytes and content of immunoglobulins G, A, M, as well as further activation and fixation of immune response. On the whole, indices of immune status improved after a course of treatment in 97.8% patients of the main group and in 67.5% patients of the control group simultaneously with positive dynamics of clinical symptomatic. These indices have become particularly better after 6 months in post-treatemnt period that evidences the prolonged efficacy of ST in contrast to other methods of treatment.

Republican Specialized Scientific Practical Medical Center of Phthisiatry and Pulmonology Uzbekistan

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