-
Something wrong with this record ?
Clinical, diagnostic and molecular genetic features of chronic mixed-hepatitis B C in Uzbekistan
Botir Тadjiev
Medical and Health Science Journal.
2010 ;
3 (3) :
47-51.
Language English Country Czech Republic
Persistent link
https://www.medvik.cz/link/bmc14048373
- Keywords
- anti-HBs,
- MeSH
- Biomarkers blood MeSH
- Hepatitis B, Chronic * genetics immunology MeSH
- Hepatitis C, Chronic * genetics immunology MeSH
- DNA, Viral MeSH
- Enzyme-Linked Immunosorbent Assay statistics & numerical data MeSH
- Genotype MeSH
- Hepacivirus genetics immunology MeSH
- Hepatitis B e Antigens genetics immunology MeSH
- Hepatitis B Core Antigens genetics immunology MeSH
- Hepatitis B Surface Antigens genetics immunology MeSH
- Hepatitis C Antigens genetics immunology MeSH
- Immunoglobulin G analysis immunology MeSH
- Immunoglobulin M analysis immunology MeSH
- Liver Cirrhosis pathology MeSH
- Biopsy, Needle MeSH
- Coinfection * genetics immunology MeSH
- Humans MeSH
- Polymerase Chain Reaction statistics & numerical data MeSH
- RNA, Viral MeSH
- Viral Load statistics & numerical data MeSH
- Genes, Viral * MeSH
- Hepatitis B virus genetics immunology MeSH
- Check Tag
- Humans MeSH
- Geographicals
- Uzbekistan MeSH
The study established the frequency of detection of antigens and antibodies to HBV and HCV in mixed-hepatitis B C. The highest rates of detection of serological markers were observed in the identification in the blood the HBV genotype D and HCV genotype 1b. This phenomenon can be explained by the high replicative and antigenic activity of viruses in these genotypes, resulting in a high viral load in blood, compared with HBV genotypes A and C, HCV genotypes 3a and 2a. In this regard, the use of ELISA technique in combination with PCR diagnosis and genotyping of viruses is considered as desirable for the etiological interpretation of viral hepatitis. This approach also will enhance achieving the correct diagnosis and adequate choice of treatment programs
References provided by Crossref.org
Bibliography, etc.
Literatura
- 000
- 00000naa a2200000 a 4500
- 001
- bmc14048373
- 003
- CZ-PrNML
- 005
- 20141209110525.0
- 007
- ta
- 008
- 140308s2010 xr f 000 0eng||
- 009
- eAR
- 024 7_
- $a 10.15208/mhsj.2010.45 $2 doi
- 040 __
- $a ABA008 $d ABA008 $e AACR2 $b cze
- 041 0_
- $a eng
- 044 __
- $a xr
- 100 1_
- $a Tadjiev, Botir $u Scientific-Research Institute of Virology, Tashkent Pediatric Medical Institute, Uzbekistan
- 245 10
- $a Clinical, diagnostic and molecular genetic features of chronic mixed-hepatitis B C in Uzbekistan / $c Botir Тadjiev
- 504 __
- $a Literatura
- 520 9_
- $a The study established the frequency of detection of antigens and antibodies to HBV and HCV in mixed-hepatitis B C. The highest rates of detection of serological markers were observed in the identification in the blood the HBV genotype D and HCV genotype 1b. This phenomenon can be explained by the high replicative and antigenic activity of viruses in these genotypes, resulting in a high viral load in blood, compared with HBV genotypes A and C, HCV genotypes 3a and 2a. In this regard, the use of ELISA technique in combination with PCR diagnosis and genotyping of viruses is considered as desirable for the etiological interpretation of viral hepatitis. This approach also will enhance achieving the correct diagnosis and adequate choice of treatment programs
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a genotyp $7 D005838
- 650 12
- $a chronická hepatitida B $x genetika $x imunologie $7 D019694
- 650 12
- $a chronická hepatitida C $x genetika $x imunologie $7 D019698
- 650 _2
- $a virová nálož $x statistika a číselné údaje $7 D019562
- 650 _2
- $a ELISA $x statistika a číselné údaje $7 D004797
- 650 _2
- $a polymerázová řetězová reakce $x statistika a číselné údaje $7 D016133
- 650 _2
- $a biologické markery $x krev $7 D015415
- 650 12
- $a virové geny $7 D005814
- 650 _2
- $a DNA virů $7 D004279
- 650 _2
- $a RNA virová $7 D012367
- 650 _2
- $a jaterní cirhóza $x patologie $7 D008103
- 650 _2
- $a jehlová biopsie $7 D001707
- 650 12
- $a koinfekce $x genetika $x imunologie $7 D060085
- 650 _2
- $a Hepacivirus $x genetika $x imunologie $7 D016174
- 650 _2
- $a virus hepatitidy B $x genetika $x imunologie $7 D006515
- 650 _2
- $a hepatitida B - antigeny jádrové $x genetika $x imunologie $7 D006512
- 650 _2
- $a hepatitida B - antigeny povrchové $x genetika $x imunologie $7 D006514
- 650 _2
- $a hepatitida B - antigeny e $x genetika $x imunologie $7 D006513
- 650 _2
- $a hepatitida C - antigeny $x genetika $x imunologie $7 D018936
- 650 _2
- $a imunoglobulin G $x analýza $x imunologie $7 D007074
- 650 _2
- $a imunoglobulin M $x analýza $x imunologie $7 D007075
- 651 _2
- $a Uzbekistán $7 D014610
- 653 00
- $a anti-HBs
- 773 0_
- $t Medical and health science journal $x 1804-1884 $g Roč. 3, č. 3 (2010), s. 47-51 $w MED00177704
- 856 41
- $u http://academicpublishingplatforms.com/journal.php?journal=MHSJ $y domovská stránka časopisu - plný text volně přístupný
- 910 __
- $a ABA008 $y 4 $z 0
- 990 __
- $a 20140306080010 $b ABA008
- 991 __
- $a 20141209110617 $b ABA008
- 999 __
- $a ok $b bmc $g 1015474 $s 846928
- BAS __
- $a 3 $a 4 $a PRD
- BMC __
- $a 2010 $b 3 $c 3 $d 47-51 $i 1804-1884 $m Medical and Health Science Journal $n Med. Health Sci. J. $x MED00177704
- LZP __
- $c NLK188 $d 20141209 $a NLK 2014-17/vt
