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Clinical, diagnostic and molecular genetic features of chronic mixed-hepatitis B C in Uzbekistan
Botir Тadjiev
Medical and Health Science Journal.
2010 ;
3 (3) :
47-51.
Jazyk angličtina Země Česko
Perzistentní odkaz
https://www.medvik.cz/link/bmc14048373
- Klíčová slova
- anti-HBs,
- MeSH
- biologické markery krev MeSH
- chronická hepatitida B * genetika imunologie MeSH
- chronická hepatitida C * genetika imunologie MeSH
- DNA virů MeSH
- ELISA statistika a číselné údaje MeSH
- genotyp MeSH
- Hepacivirus genetika imunologie MeSH
- hepatitida B - antigeny e genetika imunologie MeSH
- hepatitida B - antigeny jádrové genetika imunologie MeSH
- hepatitida B - antigeny povrchové genetika imunologie MeSH
- hepatitida C - antigeny genetika imunologie MeSH
- imunoglobulin G analýza imunologie MeSH
- imunoglobulin M analýza imunologie MeSH
- jaterní cirhóza patologie MeSH
- jehlová biopsie MeSH
- koinfekce * genetika imunologie MeSH
- lidé MeSH
- polymerázová řetězová reakce statistika a číselné údaje MeSH
- RNA virová MeSH
- virová nálož statistika a číselné údaje MeSH
- virové geny * MeSH
- virus hepatitidy B genetika imunologie MeSH
- Check Tag
- lidé MeSH
- Geografické názvy
- Uzbekistán MeSH
The study established the frequency of detection of antigens and antibodies to HBV and HCV in mixed-hepatitis B C. The highest rates of detection of serological markers were observed in the identification in the blood the HBV genotype D and HCV genotype 1b. This phenomenon can be explained by the high replicative and antigenic activity of viruses in these genotypes, resulting in a high viral load in blood, compared with HBV genotypes A and C, HCV genotypes 3a and 2a. In this regard, the use of ELISA technique in combination with PCR diagnosis and genotyping of viruses is considered as desirable for the etiological interpretation of viral hepatitis. This approach also will enhance achieving the correct diagnosis and adequate choice of treatment programs
Bibliografie atd.
Literatura
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