V roce 2009 došlo k inovaci screeningu kolorektálního karcinomu s cílem dosažení lepších výsledků. Vedle testů guajakových se začaly používat testy imunochemické s vyšší senzitivitou i specificitou. Při zvýšení adherence české populace však došlo i k výraznému zvýšení pozitivity imunochemických testů s následnou obavou z vyšší falešné pozitivity. Doposud v ČR neexistoval přehled o typech jednotlivých imunochemických testů a jejich nastavení (cut-off).

In 2009, innovations in colorectal cancer screening were made with the aim of achieving better results. Aside from stool guaiac tests, immunochemical tests with higher sensitivity and specificity were also introduced. With increasing adherence in the Czech population, however, there was also a significant increase in the number of positive immunochemical tests, which can lead to a fear of a higher number of false positives. In the Czech Republic, there has not yet been a survey published of the various types of immunochemical tests and their cut-off settings. Key words: screening – colorectal cancer – immunochemical test – general practitioner The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study. The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers. Submitted: 6. 2. 2015 Accepted: 17. 5. 2015

Ústav všeobecného lékařství 1 LF UK Praha

Variability tests for occult blood used by general practitioners in screening for colorectal cancer in the Czech Republic

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