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Je něco špatně v tomto záznamu ?
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer
TR. Rebbeck, N. Mitra, F. Wan, OM. Sinilnikova, S. Healey, L. McGuffog, S. Mazoyer, G. Chenevix-Trench, DF. Easton, AC. Antoniou, KL. Nathanson, . , Y. Laitman, A. Kushnir, S. Paluch-Shimon, R. Berger, J. Zidan, E. Friedman, H. Ehrencrona, M....
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, pozorovací studie, Research Support, N.I.H., Extramural, práce podpořená grantem
NLK
Open Access Digital Library
od 1998-01-01 do Před 6 měsíci
Medline Complete (EBSCOhost)
od 1998-01-07 do Před 1 měsícem
PubMed
25849179
DOI
10.1001/jama.2014.5985
Knihovny.cz E-zdroje
- MeSH
- dospělí MeSH
- genetická predispozice k nemoci * MeSH
- geny BRCA1 * MeSH
- geny BRCA2 * MeSH
- heterozygot MeSH
- lidé středního věku MeSH
- lidé MeSH
- mutace * MeSH
- nádory prsu genetika MeSH
- nádory vaječníků genetika MeSH
- nukleotidy MeSH
- rizikové faktory MeSH
- věk při počátku nemoci MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
- práce podpořená grantem MeSH
- Research Support, N.I.H., Extramural MeSH
IMPORTANCE: Limited information about the relationship between specific mutations in BRCA1 or BRCA2 (BRCA1/2) and cancer risk exists. OBJECTIVE: To identify mutation-specific cancer risks for carriers of BRCA1/2. DESIGN, SETTING, AND PARTICIPANTS: Observational study of women who were ascertained between 1937 and 2011 (median, 1999) and found to carry disease-associated BRCA1 or BRCA2 mutations. The international sample comprised 19,581 carriers of BRCA1 mutations and 11,900 carriers of BRCA2 mutations from 55 centers in 33 countries on 6 continents. We estimated hazard ratios for breast and ovarian cancer based on mutation type, function, and nucleotide position. We also estimated RHR, the ratio of breast vs ovarian cancer hazard ratios. A value of RHR greater than 1 indicated elevated breast cancer risk; a value of RHR less than 1 indicated elevated ovarian cancer risk. EXPOSURES: Mutations of BRCA1 or BRCA2. MAIN OUTCOMES AND MEASURES: Breast and ovarian cancer risks. RESULTS: Among BRCA1 mutation carriers, 9052 women (46%) were diagnosed with breast cancer, 2317 (12%) with ovarian cancer, 1041 (5%) with breast and ovarian cancer, and 7171 (37%) without cancer. Among BRCA2 mutation carriers, 6180 women (52%) were diagnosed with breast cancer, 682 (6%) with ovarian cancer, 272 (2%) with breast and ovarian cancer, and 4766 (40%) without cancer. In BRCA1, we identified 3 breast cancer cluster regions (BCCRs) located at c.179 to c.505 (BCCR1; RHR = 1.46; 95% CI, 1.22-1.74; P = 2 × 10(-6)), c.4328 to c.4945 (BCCR2; RHR = 1.34; 95% CI, 1.01-1.78; P = .04), and c. 5261 to c.5563 (BCCR2', RHR = 1.38; 95% CI, 1.22-1.55; P = 6 × 10(-9)). We also identified an ovarian cancer cluster region (OCCR) from c.1380 to c.4062 (approximately exon 11) with RHR = 0.62 (95% CI, 0.56-0.70; P = 9 × 10(-17)). In BRCA2, we observed multiple BCCRs spanning c.1 to c.596 (BCCR1; RHR = 1.71; 95% CI, 1.06-2.78; P = .03), c.772 to c.1806 (BCCR1'; RHR = 1.63; 95% CI, 1.10-2.40; P = .01), and c.7394 to c.8904 (BCCR2; RHR = 2.31; 95% CI, 1.69-3.16; P = .00002). We also identified 3 OCCRs: the first (OCCR1) spanned c.3249 to c.5681 that was adjacent to c.5946delT (6174delT; RHR = 0.51; 95% CI, 0.44-0.60; P = 6 × 10(-17)). The second OCCR spanned c.6645 to c.7471 (OCCR2; RHR = 0.57; 95% CI, 0.41-0.80; P = .001). Mutations conferring nonsense-mediated decay were associated with differential breast or ovarian cancer risks and an earlier age of breast cancer diagnosis for both BRCA1 and BRCA2 mutation carriers. CONCLUSIONS AND RELEVANCE: Breast and ovarian cancer risks varied by type and location of BRCA1/2 mutations. With appropriate validation, these data may have implications for risk assessment and cancer prevention decision making for carriers of BRCA1 and BRCA2 mutations.
AO Città della Salute e della Scienza Turin Italy
Cancer Risk Program Helen Diller Family Cancer Center University of California San Francisco
Center for Genomic Medicine Rigshospitalet Copenhagen University Hospital Copenhagen Denmark
Center for Medical Genetics Ghent University Ghent Belgium
Centre de Recherche en Cancérologie de Lyon UMR Inserm Centre Léon Bérard Lyon France
Clinical Genetics Department St Georges Hospital University of London United Kingdom
Clinical Genetics Service Memorial Sloan Kettering Cancer Center New York New York
Dana Farber Cancer Institute Boston Massachusetts
Department of Clinical Genetics Aarhus University Hospital Aarhus N Denmark
Department of Clinical Genetics Academic Medical Center Amsterdam The Netherlands
Department of Clinical Genetics Helsinki University Central Hospital Helsinki Finland
Department of Clinical Genetics Karolinska University Hospital Stockholm Sweden
Department of Clinical Genetics Odense University Hospital Odense C Denmark
Department of Clinical Genetics Royal Devon and Exeter Hospital Exeter United Kingdom
Department of Clinical Genetics Vejle Hospital Vejle Denmark
Department of Clinical Genetics VU University Medical Centre Amsterdam The Netherlands
Department of Dermatology University of Utah School of Medicine Salt Lake City
Department of Epidemiology Cancer Prevention Institute of California Fremont
Department of Epidemiology Columbia University New York New York
Department of Genetics and Pathology Pomeranian Medical University Szczecin Poland
Department of Genetics Portuguese Oncology Institute Porto Portugal
Department of Genetics University Medical Center Groningen University Groningen The Netherlands
Department of Genetics University of Pretoria Pretoria South Africa
Department of Gynaecology and Obstetrics University Hospital Ulm Ulm Germany
Department of Gynecologic Oncology Roswell Park Cancer Institute Buffalo New York
Department of Health Research and Policy Stanford University School of Medicine Stanford California
Department of Health Sciences Research Mayo Clinic Rochester Minnesota
Department of Hematology and Oncology University of Kansas Medical Center Kansas City
Department of Human Genetics Radboud University Nijmegen Medical Centre Nijmegen The Netherlands
Department of Laboratory Medicine and Pathology Mayo Clinic Rochester Minnesota
Department of Medical Genetics University Medical Center Utrecht Utrecht The Netherlands
Department of Medical Oncology Beth Israel Deaconess Medical Center Boston Massachusetts
Department of Medicine and Genetics University of California San Francisco
Department of Molecular Genetics National Institute of Oncology Budapest Hungary
Department of Molecular Medicine University La Sapienza Rome Italy
Department of OB GYN and Comprehensive Cancer Center Medical University of Vienna Vienna Austria
Department of Oncology Lund University Lund Sweden
Department of Oncology Sahlgrenska University Hospital Gothenburg Sweden
Department of Pathology and Laboratory Medicine University of Kansas Medical Center Kansas City
Department of Population Sciences Beckman Research Institute of City of Hope Duarte California
Department of Radiation Sciences Oncology Umeå University Umeå Sweden
Department of Surgery Daerim St Mary's Hospital Seoul Korea
Department of Surgery Soonchunhyang University and Hospital Seoul Korea
Departments of Pediatrics and Medicine Columbia University New York New York
Division of Cancer Prevention and Genetics Istituto Europeo di Oncologia Milan Italy
Evanston Hospital Evanston Illinois
Family Cancer Clinic Netherlands Cancer Institute Amsterdam The Netherlands
Ferguson Smith Centre for Clinical Genetics Yorkhill Hospitals Glasgow United Kingdom
Fox Chase Cancer Center Philadelphia Pennsylvania
Genetic Counseling Unit Hereditary Cancer Program IDIBGI Catalan Institute of Oncology Girona Spain
GOG Statistical and Data Center Buffalo New York
Human Genetics Group and Genotyping Unit Spanish National Cancer Centre Madrid Spain
Human Genetics Group Spanish National Cancer Centre Madrid Spain
Immunology and Molecular Oncology Unit Veneto Institute of Oncology IOV IRCCS Padua Italy
INSERM U1052 CNRS UMR5286 Université Lyon 1 Centre de Recherche en Cancérologie de Lyon Lyon France
Institut Curie Department of Tumour Biology Paris France
Institute for Medical Informatics Statistics and Epidemiology University of Leipzig Leipzig Germany
Institute of Biology and Molecular Genetics Universidad de Valladolid Valladolid Spain
Institute of Cell and Molecular Pathology Hannover Medical School Hannover Germany
Institute of Human Genetics Campus Virchov Klinikum Charite Berlin Berlin Germany
Institute of Human Genetics Technical University Dresden Dresden Germany
Institute of Human Genetics University Medical Center Schleswig Holstein Campus Kiel Germany
Institute of Human Genetics University of Regensburg Regensburg Germany
Institute of Medical Genetics Catholic University A Gemelli Hospital Rome Italy
Laboratoire d'Oncogénétique Hôpital René Huguenin Institut Curie Saint Cloud France
Laboratoire d'Oncologie Moléculaire Humaine Centre Oscar Lambret Lille France
Latvian Biomedical Research and Study Centre Riga Latvia
Lombardi Comprehensive Cancer Center Georgetown University Washington DC
Molecular Genetics Laboratory Cruces University Hospital Barakaldo Bizkaia Spain
Molecular Genetics of Breast Cancer Deutsches Krebsforschungszentrum Heidelberg Germany
Molecular Genetics of Breast Cancer Deutsches Krebsforschungszentrum Lahore Pakistan
Molecular Oncology Laboratory Hospital Clinico San Carlos IdISSC Madrid Spain
N N Petrov Institute of Oncology St Petersburg Russia
New York University New York New York
Northern Ireland Regional Genetics Centre Belfast City Hospital Belfast United Kingdom
NorthShore University HealthSystem Department of Medicine Evanston Illinois
Ohio State Good Samaritan Hospital Cincinnati
Oncogénétique Clinique Hôpital René Huguenin Institut Curie Saint Cloud France
Oncology Institute Rivkah Ziv Medical Center Zefat Israel
Oncology Institute Sheba Medical Center Tel Hashomer Israel
Oncology Service Hospital de la Santa Creu i Sant Pau Barcelona Spain
Oxford Regional Genetics Service Churchill Hospital Oxford United Kingdom
Service de Génétique Centre Hospitalier Universitaire Bretonneau Tours France
Sheba Medical Center Tel Aviv Israel
Sheffield Clinical Genetics Service Sheffield Children's Hospital Sheffield United Kingdom
South East of Scotland Regional Genetics Service Western General Hospital Edinburgh United Kingdom
South East Thames Regional Genetics Service Guy's Hospital London United Kingdom
South West Regional Genetics Service Bristol United Kingdom
Susanne Levy Gertner Oncogenetics Unit Sheba Medical Center Tel Hashomer Israel
Tufts University Medford Massachusetts
Unité d'Oncogénétique CLCC Paul Strauss Strasbourg France
University of North Carolina Chapel Hill
University of Texas MD Anderson Cancer Center Houston
Wessex Clinical Genetics Service Princess Anne Hospital Southampton United Kingdom
Citace poskytuje Crossref.org
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- $a Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer / $c TR. Rebbeck, N. Mitra, F. Wan, OM. Sinilnikova, S. Healey, L. McGuffog, S. Mazoyer, G. Chenevix-Trench, DF. Easton, AC. Antoniou, KL. Nathanson, . , Y. Laitman, A. Kushnir, S. Paluch-Shimon, R. Berger, J. Zidan, E. Friedman, H. Ehrencrona, M. Stenmark-Askmalm, Z. Einbeigi, N. Loman, K. Harbst, J. Rantala, B. Melin, D. Huo, OI. Olopade, J. Seldon, PA. Ganz, RL. Nussbaum, SB. Chan, K. Odunsi, SA. Gayther, SM. Domchek, BK. Arun, KH. Lu, G. Mitchell, BY. Karlan, C. Walsh, J. Lester, AK. Godwin, H. Pathak, E. Ross, MB. Daly, AS. Whittemore, EM. John, A. Miron, MB. Terry, WK. Chung, DE. Goldgar, SS. Buys, R. Janavicius, L. Tihomirova, N. Tung, CM. Dorfling, EJ. van Rensburg, L. Steele, SL. Neuhausen, YC. Ding, B. Ejlertsen, AM. Gerdes, Tv. Hansen, T. Ramón y Cajal, A. Osorio, J. Benitez, J. Godino, MI. Tejada, M. Duran, JN. Weitzel, KA. Bobolis, SR. Sand, A. Fontaine, A. Savarese, B. Pasini, B. Peissel, B. Bonanni, D. Zaffaroni, F. Vignolo-Lutati, G. Scuvera, G. Giannini, L. Bernard, M. Genuardi, P. Radice, R. Dolcetti, S. Manoukian, V. Pensotti, V. Gismondi, D. Yannoukakos, F. Fostira, J. Garber, D. Torres, MU. Rashid, U. Hamann, S. Peock, D. Frost, R. Platte, DG. Evans, R. Eeles, R. Davidson, D. Eccles, T. Cole, J. Cook, C. Brewer, S. Hodgson, PJ. Morrison, L. Walker, ME. Porteous, MJ. Kennedy, L. Izatt, J. Adlard, A. Donaldson, S. Ellis, P. Sharma, RK. Schmutzler, B. Wappenschmidt, A. Becker, K. Rhiem, E. Hahnen, C. Engel, A. Meindl, S. Engert, N. Ditsch, N. Arnold, HJ. Plendl, C. Mundhenke, D. Niederacher, M. Fleisch, C. Sutter, CR. Bartram, N. Dikow, S. Wang-Gohrke, D. Gadzicki, D. Steinemann, K. Kast, M. Beer, R. Varon-Mateeva, A. Gehrig, BH. Weber, D. Stoppa-Lyonnet, OM. Sinilnikova, S. Mazoyer, C. Houdayer, M. Belotti, M. Gauthier-Villars, F. Damiola, N. Boutry-Kryza, C. Lasset, H. Sobol, JP. Peyrat, D. Muller, JP. Fricker, MA. Collonge-Rame, I. Mortemousque, C. Nogues, E. Rouleau, C. Isaacs, A. De Paepe, B. Poppe, K. Claes, K. De Leeneer, M. Piedmonte, G. Rodriguez, K. Wakely, J. Boggess, SV. Blank, J. Basil, M. Azodi, KA. Phillips, T. Caldes, M. de la Hoya, A. Romero, H. Nevanlinna, K. Aittomäki, AH. van der Hout, FB. Hogervorst, S. Verhoef, JM. Collée, C. Seynaeve, JC. Oosterwijk, JJ. Gille, JT. Wijnen, EB. Gómez Garcia, CM. Kets, MG. Ausems, CM. Aalfs, P. Devilee, AR. Mensenkamp, A. Kwong, E. Olah, J. Papp, O. Diez, C. Lazaro, E. Darder, I. Blanco, M. Salinas, A. Jakubowska, J. Lubinski, J. Gronwald, K. Jaworska-Bieniek, K. Durda, G. Sukiennicki, T. Huzarski, T. Byrski, C. Cybulski, A. Toloczko-Grabarek, E. Złowocka-Perłowska, J. Menkiszak, A. Arason, RB. Barkardottir, J. Simard, R. Laframboise, M. Montagna, S. Agata, E. Alducci, A. Peixoto, MR. Teixeira, AB. Spurdle, MH. Lee, SK. Park, SW. Kim, TM. Friebel, FJ. Couch, NM. Lindor, VS. Pankratz, L. Guidugli, X. Wang, M. Tischkowitz, L. Foretova, J. Vijai, K. Offit, M. Robson, R. Rau-Murthy, N. Kauff, A. Fink-Retter, CF. Singer, C. Rappaport, D. Gschwantler-Kaulich, G. Pfeiler, MK. Tea, A. Berger, MH. Greene, PL. Mai, EN. Imyanitov, AE. Toland, L. Senter, A. Bojesen, IS. Pedersen, AB. Skytte, L. Sunde, M. Thomassen, ST. Moeller, TA. Kruse, UB. Jensen, MA. Caligo, P. Aretini, SH. Teo, CG. Selkirk, PJ. Hulick, I. Andrulis,
- 520 9_
- $a IMPORTANCE: Limited information about the relationship between specific mutations in BRCA1 or BRCA2 (BRCA1/2) and cancer risk exists. OBJECTIVE: To identify mutation-specific cancer risks for carriers of BRCA1/2. DESIGN, SETTING, AND PARTICIPANTS: Observational study of women who were ascertained between 1937 and 2011 (median, 1999) and found to carry disease-associated BRCA1 or BRCA2 mutations. The international sample comprised 19,581 carriers of BRCA1 mutations and 11,900 carriers of BRCA2 mutations from 55 centers in 33 countries on 6 continents. We estimated hazard ratios for breast and ovarian cancer based on mutation type, function, and nucleotide position. We also estimated RHR, the ratio of breast vs ovarian cancer hazard ratios. A value of RHR greater than 1 indicated elevated breast cancer risk; a value of RHR less than 1 indicated elevated ovarian cancer risk. EXPOSURES: Mutations of BRCA1 or BRCA2. MAIN OUTCOMES AND MEASURES: Breast and ovarian cancer risks. RESULTS: Among BRCA1 mutation carriers, 9052 women (46%) were diagnosed with breast cancer, 2317 (12%) with ovarian cancer, 1041 (5%) with breast and ovarian cancer, and 7171 (37%) without cancer. Among BRCA2 mutation carriers, 6180 women (52%) were diagnosed with breast cancer, 682 (6%) with ovarian cancer, 272 (2%) with breast and ovarian cancer, and 4766 (40%) without cancer. In BRCA1, we identified 3 breast cancer cluster regions (BCCRs) located at c.179 to c.505 (BCCR1; RHR = 1.46; 95% CI, 1.22-1.74; P = 2 × 10(-6)), c.4328 to c.4945 (BCCR2; RHR = 1.34; 95% CI, 1.01-1.78; P = .04), and c. 5261 to c.5563 (BCCR2', RHR = 1.38; 95% CI, 1.22-1.55; P = 6 × 10(-9)). We also identified an ovarian cancer cluster region (OCCR) from c.1380 to c.4062 (approximately exon 11) with RHR = 0.62 (95% CI, 0.56-0.70; P = 9 × 10(-17)). In BRCA2, we observed multiple BCCRs spanning c.1 to c.596 (BCCR1; RHR = 1.71; 95% CI, 1.06-2.78; P = .03), c.772 to c.1806 (BCCR1'; RHR = 1.63; 95% CI, 1.10-2.40; P = .01), and c.7394 to c.8904 (BCCR2; RHR = 2.31; 95% CI, 1.69-3.16; P = .00002). We also identified 3 OCCRs: the first (OCCR1) spanned c.3249 to c.5681 that was adjacent to c.5946delT (6174delT; RHR = 0.51; 95% CI, 0.44-0.60; P = 6 × 10(-17)). The second OCCR spanned c.6645 to c.7471 (OCCR2; RHR = 0.57; 95% CI, 0.41-0.80; P = .001). Mutations conferring nonsense-mediated decay were associated with differential breast or ovarian cancer risks and an earlier age of breast cancer diagnosis for both BRCA1 and BRCA2 mutation carriers. CONCLUSIONS AND RELEVANCE: Breast and ovarian cancer risks varied by type and location of BRCA1/2 mutations. With appropriate validation, these data may have implications for risk assessment and cancer prevention decision making for carriers of BRCA1 and BRCA2 mutations.
- 650 _2
- $a dospělí $7 D000328
- 650 _2
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- $a Wan, Fei $u Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
- 700 1_
- $a Sinilnikova, Olga M $u Centre de Recherche en Cancérologie de Lyon, UMR Inserm, Centre Léon Bérard, Lyon, France.
- 700 1_
- $a Healey, Sue $u Department of Genetics and Computational Biology, Queensland Institute of Medical Research, Brisbane, Australia.
- 700 1_
- $a McGuffog, Lesley $u Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
- 700 1_
- $a Mazoyer, Sylvie $u Centre de Recherche en Cancérologie de Lyon, UMR Inserm, Centre Léon Bérard, Lyon, France.
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- $a Easton, Douglas F $u Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
- 700 1_
- $a Antoniou, Antonis C $u Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom. $7 gn_A_00007463
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- $a Nathanson, Katherine L $u Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia6Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
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- 700 1_
- $a Laitman, Yael $u Sheba Medical Center, Tel Aviv, Israel.
- 700 1_
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- $a Friedman, Eitan $u Sheba Medical Center, Tel Aviv, Israel.
- 700 1_
- $a Ehrencrona, Hans $u Department of Oncology, Lund University, Lund, Sweden12Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
- 700 1_
- $a Stenmark-Askmalm, Marie $u Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
- 700 1_
- $a Einbeigi, Zakaria $u Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden.
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- 700 1_
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- 700 1_
- $a Melin, Beatrice $u Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden.
- 700 1_
- $a Huo, Dezheng $u Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois.
- 700 1_
- $a Olopade, Olufunmilayo I $u Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois.
- 700 1_
- $a Seldon, Joyce $u UCLA Schools of Medicine and Public Health, Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, Los Angeles, California.
- 700 1_
- $a Ganz, Patricia A $u UCLA Schools of Medicine and Public Health, Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, Los Angeles, California.
- 700 1_
- $a Nussbaum, Robert L $u Department of Medicine and Genetics, University of California, San Francisco.
- 700 1_
- $a Chan, Salina B $u Cancer Risk Program, Helen Diller Family Cancer Center, University of California, San Francisco.
- 700 1_
- $a Odunsi, Kunle $u Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, New York.
- 700 1_
- $a Gayther, Simon A $u Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles.
- 700 1_
- $a Domchek, Susan M $u Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia6Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
- $a John, Esther M $u Department of Epidemiology, Cancer Prevention Institute of California, Fremont.
- 700 1_
- $a Miron, Alexander $u Dana-Farber Cancer Institute, Boston, Massachusetts.
- 700 1_
- $a Terry, Mary Beth $u Department of Epidemiology, Columbia University, New York, New York.
- 700 1_
- $a Chung, Wendy K $u Departments of Pediatrics and Medicine, Columbia University, New York, New York.
- 700 1_
- $a Goldgar, David E $u Department of Dermatology, University of Utah School of Medicine, Salt Lake City.
- 700 1_
- $a Buys, Saundra S $u Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City.
- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
- $a Neuhausen, Susan L $u Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California.
- 700 1_
- $a Ding, Yuan Chun $u Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California.
- 700 1_
- $a Ejlertsen, Bent $u Departments of Oncology or Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
- 700 1_
- $a Gerdes, Anne-Marie $u Departments of Oncology or Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
- 700 1_
- $a Hansen, Thomas v O $u Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
- 700 1_
- $a Ramón y Cajal, Teresa $u Oncology Service, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
- 700 1_
- $a Osorio, Ana $u Human Genetics Group, Spanish National Cancer Centre (CNIO), and Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain.
- 700 1_
- $a Benitez, Javier $u Human Genetics Group and Genotyping Unit, Spanish National Cancer Centre (CNIO), and Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain.
- 700 1_
- $a Godino, Javier $u Hospital clinico Universitario "Lozano Blesa," Instituto de investigación sanitaria de Aragón (IIS), Zaragoza, Spain.
- 700 1_
- $a Tejada, Maria-Isabel $u Molecular Genetics Laboratory (Department of Genetics), Cruces University Hospital Barakaldo, Bizkaia, Spain.
- 700 1_
- $a Duran, Mercedes $u Institute of Biology and Molecular Genetics. Universidad de Valladolid (IBGM-UVA), Valladolid, Spain.
- 700 1_
- $a Weitzel, Jeffrey N $u Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California.
- 700 1_
- $a Bobolis, Kristie A $u Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California.
- 700 1_
- $a Sand, Sharon R $u Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California.
- 700 1_
- $a Fontaine, Annette $u Clinical Cancer Genetics, City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California.
- 700 1_
- $a Savarese, Antonella $u Unit of Genetic Counselling, Medical Oncology Department, Istituto Nazionale Tumori Regina Elena, Rome, Italy.
- 700 1_
- $a Pasini, Barbara $u Department of Medical Science, University of Turin, and AO Città della Salute e della Scienza, Turin, Italy.
- 700 1_
- $a Peissel, Bernard $u Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy.
- 700 1_
- $a Bonanni, Bernardo $u Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy.
- 700 1_
- $a Zaffaroni, Daniela $u Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy.
- 700 1_
- $a Vignolo-Lutati, Francesca $u AO Città della Salute e della Scienza, Turin, Italy.
- 700 1_
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- 700 1_
- $a Giannini, Giuseppe $u Department of Molecular Medicine, University La Sapienza, Rome, Italy.
- 700 1_
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- 700 1_
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- 700 1_
- $a Radice, Paolo $u Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy60IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.
- 700 1_
- $a Dolcetti, Riccardo $u Cancer Bioimmunotherapy Unit, Centro di Riferimento Oncologico, IRCCSCRO Aviano National Cancer Institute, Aviano (PN), Italy.
- 700 1_
- $a Manoukian, Siranoush $u Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy.
- 700 1_
- $a Pensotti, Valeria $u Cogentech Cancer Genetic Test Laboratory, Milan, Italy60IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.
- 700 1_
- $a Gismondi, Viviana $u Unit of Hereditary Cancer, IRCCS AOU San Martino-IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.
- 700 1_
- $a Yannoukakos, Drakoulis $u Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research "Demokritos" Aghia Paraskevi Attikis, Athens, Greece.
- 700 1_
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- 700 1_
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- 700 1_
- $a Torres, Diana $u Instituto de Genética Humana, Pontificia Universidad Javeriana, Bogotá, Colombia65Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
- 700 1_
- $a Rashid, Muhammad Usman $u Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany 66Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, Pakistan.
- 700 1_
- $a Hamann, Ute $u Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
- 700 1_
- $a Peock, Susan $u Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
- 700 1_
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- 700 1_
- $a Platte, Radka $u Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
- 700 1_
- $a Evans, D Gareth $u Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals, NHS Foundation Trust, Manchester, United Kingdom.
- 700 1_
- $a Eeles, Rosalind $u Oncogenetics Team, Institute of Cancer Research and Royal Marsden, NHS Foundation Trust, London, United Kingdom.
- 700 1_
- $a Davidson, Rosemarie $u Ferguson-Smith Centre for Clinical Genetics, Yorkhill Hospitals, Glasgow, United Kingdom.
- 700 1_
- $a Eccles, Diana $u Wessex Clinical Genetics Service, Princess Anne Hospital, Southampton, United Kingdom.
- 700 1_
- $a Cole, Trevor $u West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, United Kingdom.
- 700 1_
- $a Cook, Jackie $u Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, United Kingdom.
- 700 1_
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- 700 1_
- $a Hodgson, Shirley $u Clinical Genetics Department, St Georges Hospital, University of London, United Kingdom.
- 700 1_
- $a Morrison, Patrick J $u Northern Ireland Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom.
- 700 1_
- $a Walker, Lisa $u Oxford Regional Genetics Service, Churchill Hospital, Oxford, United Kingdom.
- 700 1_
- $a Porteous, Mary E $u South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, United Kingdom.
- 700 1_
- $a Kennedy, M John $u Academic Unit of Clinical and Molecular Oncology, Trinity College Dublin and St James's Hospital, Dublin, Eire.
- 700 1_
- $a Izatt, Louise $u South East Thames Regional Genetics Service, Guy's Hospital London, United Kingdom.
- 700 1_
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- 700 1_
- $a Donaldson, Alan $u South West Regional Genetics Service, Bristol, United Kingdom.
- 700 1_
- $a Ellis, Steve $u Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
- 700 1_
- $a Sharma, Priyanka $u Department of Hematology and Oncology, University of Kansas Medical Center, Kansas City.
- 700 1_
- $a Schmutzler, Rita Katharina $u Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany.
- 700 1_
- $a Wappenschmidt, Barbara $u Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany.
- 700 1_
- $a Becker, Alexandra $u Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany.
- 700 1_
- $a Rhiem, Kerstin $u Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany.
- 700 1_
- $a Hahnen, Eric $u Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), and Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany.
- 700 1_
- $a Engel, Christoph $u Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
- 700 1_
- $a Meindl, Alfons $u Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
- 700 1_
- $a Engert, Stefanie $u Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
- 700 1_
- $a Ditsch, Nina $u Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
- 700 1_
- $a Arnold, Norbert $u Department of Gynecology and Obstetrics, University Medical Center Schleswig-Holstein, Campus Kiel, Germany.
- 700 1_
- $a Plendl, Hans Jörg $u Institute of Human Genetics, University Medical Center Schleswig-Holstein, Campus Kiel, Germany.
- 700 1_
- $a Mundhenke, Christoph $u Department of Gynecology and Obstetrics, University Medical Center Schleswig-Holstein, Campus Kiel, Germany.
- 700 1_
- $a Niederacher, Dieter $u Department of Gynaecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
- 700 1_
- $a Fleisch, Markus $u Department of Gynaecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
- 700 1_
- $a Sutter, Christian $u Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany.
- 700 1_
- $a Bartram, C R $u Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany.
- 700 1_
- $a Dikow, Nicola $u Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany.
- 700 1_
- $a Wang-Gohrke, Shan $u Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany.
- 700 1_
- $a Gadzicki, Dorothea $u Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.
- 700 1_
- $a Steinemann, Doris $u Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.
- 700 1_
- $a Kast, Karin $u Department of Gynaecology and Obstetrics, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
- 700 1_
- $a Beer, Marit $u Institute of Human Genetics, Technical University Dresden, Dresden, Germany.
- 700 1_
- $a Varon-Mateeva, Raymonda $u Institute of Human Genetics, Campus Virchov Klinikum, Charite Berlin, Berlin, Germany.
- 700 1_
- $a Gehrig, Andrea $u Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University of Würzburg, Würzburg, Germany.
- 700 1_
- $a Weber, Bernhard H $u Institute of Human Genetics, University of Regensburg, Regensburg, Germany.
- 700 1_
- $a Stoppa-Lyonnet, Dominique $u Institut Curie, Department of Tumour Biology, Paris, France98Institut Curie, INSERM U830, Paris, France99Université Paris Descartes, Sorbonne Paris Cité, France.
- 700 1_
- $a Sinilnikova, Olga M $u Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon-Centre Léon Bérard, Lyon, France101INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
- 700 1_
- $a Mazoyer, Sylvie $u INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
- 700 1_
- $a Houdayer, Claude $u Institut Curie, Department of Tumour Biology, Paris, France99Université Paris Descartes, Sorbonne Paris Cité, France.
- 700 1_
- $a Belotti, Muriel $u Institut Curie, Department of Tumour Biology, Paris, France.
- 700 1_
- $a Gauthier-Villars, Marion $u Institut Curie, Department of Tumour Biology, Paris, France.
- 700 1_
- $a Damiola, Francesca $u INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
- 700 1_
- $a Boutry-Kryza, Nadia $u Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon-Centre Léon Bérard, Lyon, France.
- 700 1_
- $a Lasset, Christine $u Université Lyon 1, CNRS UMR5558, Lyon, France103Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France.
- 700 1_
- $a Sobol, Hagay $u Département Oncologie Génétique, Prévention et Dépistage, INSERM CIC-P9502, Institut Paoli-Calmettes/Université d'Aix-Marseille II, Marseille, France.
- 700 1_
- $a Peyrat, Jean-Philippe $u Laboratoire d'Oncologie Moléculaire Humaine, Centre Oscar Lambret, Lille, France.
- 700 1_
- $a Muller, Danièle $u Unité d'Oncogénétique, CLCC Paul Strauss, Strasbourg, France.
- 700 1_
- $a Fricker, Jean-Pierre $u Unité d'Oncogénétique, CLCC Paul Strauss, Strasbourg, France.
- 700 1_
- $a Collonge-Rame, Marie-Agnès $u Service de Génétique Biologique-Histologie-Biologie du Développement et de la Reproduction, Centre Hospitalier Universitaire de Besançon, Besançon, France.
- 700 1_
- $a Mortemousque, Isabelle $u Service de Génétique, Centre Hospitalier Universitaire Bretonneau, Tours, France.
- 700 1_
- $a Nogues, Catherine $u Oncogénétique Clinique, Hôpital René Huguenin/Institut Curie, Saint-Cloud, France.
- 700 1_
- $a Rouleau, Etienne $u Laboratoire d'Oncogénétique, Hôpital René Huguenin/Institut Curie, Saint-Cloud, France.
- 700 1_
- $a Isaacs, Claudine $u Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
- 700 1_
- $a De Paepe, Anne $u Center for Medical Genetics, Ghent University, Ghent, Belgium.
- 700 1_
- $a Poppe, Bruce $u Center for Medical Genetics, Ghent University, Ghent, Belgium.
- 700 1_
- $a Claes, Kathleen $u Center for Medical Genetics, Ghent University, Ghent, Belgium.
- 700 1_
- $a De Leeneer, Kim $u Center for Medical Genetics, Ghent University, Ghent, Belgium.
- 700 1_
- $a Piedmonte, Marion $u GOG Statistical and Data Center, Buffalo, New York.
- 700 1_
- $a Rodriguez, Gustavo $u Evanston Hospital, Evanston, Illinois.
- 700 1_
- $a Wakely, Katie $u Tufts University, Medford, Massachusetts.
- 700 1_
- $a Boggess, John $u University of North Carolina, Chapel Hill.
- 700 1_
- $a Blank, Stephanie V $u New York University, New York, New York.
- 700 1_
- $a Basil, Jack $u Ohio State, Good Samaritan Hospital, Cincinnati.
- 700 1_
- $a Azodi, Masoud $u Yale University School of Medicine, New Haven, Connecticut.
- 700 1_
- $a Phillips, Kelly-Anne $u Division of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia 25Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.
- 700 1_
- $a Caldes, Trinidad $u Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.
- 700 1_
- $a de la Hoya, Miguel $u Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.
- 700 1_
- $a Romero, Atocha $u Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.
- 700 1_
- $a Nevanlinna, Heli $u Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
- 700 1_
- $a Aittomäki, Kristiina $u Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland.
- 700 1_
- $a van der Hout, Annemarie H $u Department of Genetics, University Medical Center, Groningen University, Groningen, The Netherlands.
- 700 1_
- $a Hogervorst, Frans B L $u Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, The Netherlands.
- 700 1_
- $a Verhoef, Senno $u Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, The Netherlands.
- 700 1_
- $a Collée, J Margriet $u Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands.
- 700 1_
- $a Seynaeve, Caroline $u Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands.
- 700 1_
- $a Oosterwijk, Jan C $u Department of Genetics, University Medical Center, Groningen University, Groningen, The Netherlands.
- 700 1_
- $a Gille, Johannes J P $u Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands.
- 700 1_
- $a Wijnen, Juul T $u Department of Human Genetics and Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
- 700 1_
- $a Gómez Garcia, Encarna B $u Department of Clinical Genetics and GROW, School for Oncology and Developmental Biology, MUMC, Maastricht, The Netherlands.
- 700 1_
- $a Kets, Carolien M $u Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
- 700 1_
- $a Ausems, Margreet G E M $u Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.
- 700 1_
- $a Aalfs, Cora M $u Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands.
- 700 1_
- $a Devilee, Peter $u Department of Human Genetics and Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
- 700 1_
- $a Mensenkamp, Arjen R $u Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
- 700 1_
- $a Kwong, Ava $u Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong135Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong136Department of Surgery, University of Hong Kong, Hong Kong.
- 700 1_
- $a Olah, Edith $u Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.
- 700 1_
- $a Papp, Janos $u Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.
- 700 1_
- $a Diez, Orland $u Oncogenetics Laboratory, Vall d'Hebron Institute of Oncology (VHIO), Universitat Autonoma de Barcelona, Barcelona, Spain139University Hospital of Vall d'Hebron, Barcelona, Spain.
- 700 1_
- $a Lazaro, Conxi $u Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain.
- 700 1_
- $a Darder, Esther $u Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI-Catalan Institute of Oncology, Girona, Spain.
- 700 1_
- $a Blanco, Ignacio $u Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain.
- 700 1_
- $a Salinas, Mónica $u Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain.
- 700 1_
- $a Jakubowska, Anna $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Lubinski, Jan $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Gronwald, Jacek $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Jaworska-Bieniek, Katarzyna $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland144Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw, Poland.
- 700 1_
- $a Durda, Katarzyna $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Sukiennicki, Grzegorz $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Huzarski, Tomasz $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Byrski, Tomasz $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Cybulski, Cezary $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Toloczko-Grabarek, Aleksandra $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Złowocka-Perłowska, Elżbieta $u Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Menkiszak, Janusz $u Department of Surgical Gynecology and Gynecological Oncology of Adults and Adolescents, Pomeranian Medical University, Szczecin, Poland.
- 700 1_
- $a Arason, Adalgeir $u Department of Pathology, Landspitali University Hospital, Reykjavík, Iceland147BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
- 700 1_
- $a Barkardottir, Rosa B $u Department of Pathology, Landspitali University Hospital, Reykjavík, Iceland147BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
- 700 1_
- $a Simard, Jacques $u Canada Research Chair in Oncogenetics, Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec Research Center, Quebec City, Quebec, Canada149Laval University, Quebec City, Quebec, Canada.
- 700 1_
- $a Laframboise, Rachel $u Medical Genetics Division, Centre Hospitalier Universitaire de Québec, Quebec City, Quebec, Canada151Immunology and Molecular Oncology Unit, Veneto Institute of Oncology, IOV-IRCCS, Padua, Italy.
- 700 1_
- $a Montagna, Marco $u Immunology and Molecular Oncology Unit, Veneto Institute of Oncology, IOV-IRCCS, Padua, Italy.
- 700 1_
- $a Agata, Simona $u Immunology and Molecular Oncology Unit, Veneto Institute of Oncology, IOV-IRCCS, Padua, Italy.
- 700 1_
- $a Alducci, Elisa $u Immunology and Molecular Oncology Unit, Veneto Institute of Oncology, IOV-IRCCS, Padua, Italy.
- 700 1_
- $a Peixoto, Ana $u Department of Genetics, Portuguese Oncology Institute, Porto, Portugal.
- 700 1_
- $a Teixeira, Manuel R $u Department of Genetics, Portuguese Oncology Institute, Porto, Portugal153Biomedical Sciences Institute (ICBAS), University of Porto, Portugal.
- 700 1_
- $a Spurdle, Amanda B $u Department of Genetics and Computational Biology, Queensland Institute of Medical Research, Brisbane, Australia.
- 700 1_
- $a Lee, Min Hyuk $u Department of Surgery, Soonchunhyang University and Hospital, Seoul, Korea.
- 700 1_
- $a Park, Sue K $u Department of Preventive Medicine, Seoul National University College of Medicine and Cancer Research Institute, Seoul National University, Seoul, Korea.
- 700 1_
- $a Kim, Sung-Won $u Department of Surgery, Daerim St Mary's Hospital, Seoul, Korea.
- 700 1_
- $a Friebel, Tara M $u Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
- 700 1_
- $a Couch, Fergus J $u Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota159Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
- 700 1_
- $a Lindor, Noralane M $u Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
- 700 1_
- $a Pankratz, Vernon S $u Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
- 700 1_
- $a Guidugli, Lucia $u Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
- 700 1_
- $a Wang, Xianshu $u Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
- 700 1_
- $a Tischkowitz, Marc $u Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montreal, Quebec, Canada161Department of Medical Genetics, University of Cambridge, Cambridge, United Kingdom.
- 700 1_
- $a Foretova, Lenka $u Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute and MF MU, Brno, Czech Republic.
- 700 1_
- $a Vijai, Joseph $u Clinical Genetics Service, Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York.
- 700 1_
- $a Offit, Kenneth $u Clinical Genetics Service, Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York.
- 700 1_
- $a Robson, Mark $u Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York.
- 700 1_
- $a Rau-Murthy, Rohini $u Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York.
- 700 1_
- $a Kauff, Noah $u Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York.
- 700 1_
- $a Fink-Retter, Anneliese $u Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
- 700 1_
- $a Singer, Christian F $u Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
- 700 1_
- $a Rappaport, Christine $u Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
- 700 1_
- $a Gschwantler-Kaulich, Daphne $u Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
- 700 1_
- $a Pfeiler, Georg $u Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
- 700 1_
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- 700 1_
- $a Berger, Andreas $u Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
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- 700 1_
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- 700 1_
- $a Imyanitov, Evgeny N $u N. N. Petrov Institute of Oncology, St Petersburg, Russia.
- 700 1_
- $a Toland, Amanda Ewart $u Divison of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus.
- 700 1_
- $a Senter, Leigha $u Divison of Human Genetics, Department of Internal Medicine, Comprehensive Cancer Center, Ohio State University, Columbus.
- 700 1_
- $a Bojesen, Anders $u Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark.
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- 700 1_
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- 700 1_
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- $a Thomassen, Mads $u Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark.
- 700 1_
- $a Moeller, Sanne Traasdahl $u Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark.
- 700 1_
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- $a Jensen, Uffe Birk $u Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, Denmark.
- 700 1_
- $a Caligo, Maria Adelaide $u Section of Genetic Oncology, Department of Oncology, University of Pisa and University Hospital of Pisa, Pisa, Italy.
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- $a Aretini, Paolo $u Section of Genetic Oncology, Department of Oncology, University of Pisa and University Hospital of Pisa, Pisa, Italy.
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- $a Teo, Soo-Hwang $u Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Malaysia176Department of Surgery, Faculty of Medicine, University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur, Malaysia.
- 700 1_
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- 700 1_
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- 700 1_
- $a Andrulis, Irene $u Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada.
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