Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Increased pulsatility of the intracranial blood flow spectral waveform on transcranial Doppler does not point to peripheral arterial disease in stroke patients

K. Barlinn, S. Kolieskova, RB. Shahripour, J. Kepplinger, AK. Boehme, T. Siepmann, V. Puetz, U. Bodechtel, WD. Jordan, AV. Alexandrov,

. 2015 ; 24 (1) : 189-95. [pub] 20141106

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc15031680

BACKGROUND: Peripheral arterial disease (PAD) is common in patients with acute cerebral ischemia. Indexes of resistance derived from the systolic and diastolic velocities are routinely used in diagnostic transcranial Doppler (TCD) to detect intracranial arterial disease. We sought to explore whether these indexes can predict the presence of PAD in acute cerebral ischemia. METHODS: We prospectively evaluated consecutive patients with acute cerebral ischemia. On TCD, peak-systolic and end-diastolic velocities in both middle cerebral and basilar arteries were manually measured to calculate pulsatility index (PI) and resistance index (RI). Increased resistance was defined as PI equal to 1.2 or more and RI equal to .75 or more. Ankle-brachial index (ABI) measurements were performed and an ABI equal to .9 or more was considered predictive of definite PAD. RESULTS: We included 95 patients (45 male, 50 female) aged 66 ± 9 years with a median National Institutes Health Stroke Scale score of 3 (interquartile range, 8) points. The ABI was abnormal and consistent with definite PAD in 24 of 95 (25.3%; 95% confidence interval [CI], 16.4-34.2) patients. Increased PI did not differ among patients with and without PAD (20.8% vs. 28.2%, P = .60). Only 1 patient with PAD had increased RI as opposed to 4 patients without PAD (4.2% vs. 5.6%, P = 1.0). Increased PI was not found to be an independent predictor of PAD (odds ratio [OR], .68; 95% CI, .22-2.12; P = .51). Increases in both PI and RI independently predicted arterial hypertension (OR, 1.62; 95% CI, 1.19-2.21; P = .002 and OR, 3.20; 95% CI, 1.51-6.77; P = .002, respectively). CONCLUSIONS: Our findings indicate that PAD cannot be inferred from intracranial flow parameters predictive of arterial disease and risk factors such as hypertension among patients with acute cerebral ischemia.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc15031680
003      
CZ-PrNML
005      
20151013120855.0
007      
ta
008      
151005s2015 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.jstrokecerebrovasdis.2014.08.014 $2 doi
035    __
$a (PubMed)25440327
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Barlinn, Kristian $u Department of Neurology, Comprehensive Stroke Center, University of Alabama Hospital, Birmingham, Alabama; Dresden University Stroke Center, Department of Neurology, University Hospital Carl Gustav Carus Dresden, University of Technology Dresden, Dresden, Germany. Electronic address: kristian.barlinn@uniklinikum-dresden.de.
245    10
$a Increased pulsatility of the intracranial blood flow spectral waveform on transcranial Doppler does not point to peripheral arterial disease in stroke patients / $c K. Barlinn, S. Kolieskova, RB. Shahripour, J. Kepplinger, AK. Boehme, T. Siepmann, V. Puetz, U. Bodechtel, WD. Jordan, AV. Alexandrov,
520    9_
$a BACKGROUND: Peripheral arterial disease (PAD) is common in patients with acute cerebral ischemia. Indexes of resistance derived from the systolic and diastolic velocities are routinely used in diagnostic transcranial Doppler (TCD) to detect intracranial arterial disease. We sought to explore whether these indexes can predict the presence of PAD in acute cerebral ischemia. METHODS: We prospectively evaluated consecutive patients with acute cerebral ischemia. On TCD, peak-systolic and end-diastolic velocities in both middle cerebral and basilar arteries were manually measured to calculate pulsatility index (PI) and resistance index (RI). Increased resistance was defined as PI equal to 1.2 or more and RI equal to .75 or more. Ankle-brachial index (ABI) measurements were performed and an ABI equal to .9 or more was considered predictive of definite PAD. RESULTS: We included 95 patients (45 male, 50 female) aged 66 ± 9 years with a median National Institutes Health Stroke Scale score of 3 (interquartile range, 8) points. The ABI was abnormal and consistent with definite PAD in 24 of 95 (25.3%; 95% confidence interval [CI], 16.4-34.2) patients. Increased PI did not differ among patients with and without PAD (20.8% vs. 28.2%, P = .60). Only 1 patient with PAD had increased RI as opposed to 4 patients without PAD (4.2% vs. 5.6%, P = 1.0). Increased PI was not found to be an independent predictor of PAD (odds ratio [OR], .68; 95% CI, .22-2.12; P = .51). Increases in both PI and RI independently predicted arterial hypertension (OR, 1.62; 95% CI, 1.19-2.21; P = .002 and OR, 3.20; 95% CI, 1.51-6.77; P = .002, respectively). CONCLUSIONS: Our findings indicate that PAD cannot be inferred from intracranial flow parameters predictive of arterial disease and risk factors such as hypertension among patients with acute cerebral ischemia.
650    _2
$a senioři $7 D000368
650    _2
$a tlakový index kotník-paže $7 D055109
650    _2
$a fibrilace síní $x komplikace $x ultrasonografie $7 D001281
650    _2
$a ischemie mozku $x komplikace $x ultrasonografie $7 D002545
650    12
$a mozkový krevní oběh $7 D002560
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a tranzitorní ischemická ataka $x komplikace $x ultrasonografie $7 D002546
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé středního věku $7 D008875
650    _2
$a onemocnění periferních arterií $x komplikace $x ultrasonografie $7 D058729
650    _2
$a prospektivní studie $7 D011446
650    _2
$a rizikové faktory $7 D012307
650    _2
$a cévní mozková příhoda $x komplikace $x ultrasonografie $7 D020521
650    _2
$a ultrasonografie dopplerovská transkraniální $7 D017585
655    _2
$a časopisecké články $7 D016428
700    1_
$a Kolieskova, Stanislava $u Department of Neurology, Comprehensive Stroke Center, University of Alabama Hospital, Birmingham, Alabama; International Clinical Research Centre, St. Anne's University Hospital, Brno, Czech Republic; Neurology Department, Masaryk University, Brno, Czech Republic.
700    1_
$a Shahripour, Reza Bavarsad $u Department of Neurology, Comprehensive Stroke Center, University of Alabama Hospital, Birmingham, Alabama.
700    1_
$a Kepplinger, Jessica $u Dresden University Stroke Center, Department of Neurology, University Hospital Carl Gustav Carus Dresden, University of Technology Dresden, Dresden, Germany.
700    1_
$a Boehme, Amelia K $u Department of Epidemiology, School of Public Health, University of Alabama Hospital, Birmingham, Alabama.
700    1_
$a Siepmann, Timo $u Dresden University Stroke Center, Department of Neurology, University Hospital Carl Gustav Carus Dresden, University of Technology Dresden, Dresden, Germany.
700    1_
$a Puetz, Volker $u Dresden University Stroke Center, Department of Neurology, University Hospital Carl Gustav Carus Dresden, University of Technology Dresden, Dresden, Germany.
700    1_
$a Bodechtel, Ulf $u Dresden University Stroke Center, Department of Neurology, University Hospital Carl Gustav Carus Dresden, University of Technology Dresden, Dresden, Germany.
700    1_
$a Jordan, William D $u Department of Vascular Surgery, University of Alabama Hospital, Birmingham, Alabama.
700    1_
$a Alexandrov, Andrei V $u Department of Neurology, Comprehensive Stroke Center, University of Alabama Hospital, Birmingham, Alabama; Department of Neurology, The University of Tennessee Health Science Center, Memphis, Tennessee. $7 gn_A_00003944
773    0_
$w MED00167194 $t Journal of stroke and cerebrovascular diseases the official journal of National Stroke Association $x 1532-8511 $g Roč. 24, č. 1 (2015), s. 189-95
856    41
$u https://pubmed.ncbi.nlm.nih.gov/25440327 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20151005 $b ABA008
991    __
$a 20151013121044 $b ABA008
999    __
$a ok $b bmc $g 1092556 $s 914806
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2015 $b 24 $c 1 $d 189-95 $e 20141106 $i 1532-8511 $m Journal of stroke and cerebrovascular diseases $n J Stroke Cerebrovasc Dis $x MED00167194
LZP    __
$a Pubmed-20151005

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé

Možnosti archivace