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WHO guidelines for a healthy diet and mortality from cardiovascular disease in European and American elderly: the CHANCES project
N. Jankovic, A. Geelen, MT. Streppel, LC. de Groot, JC. Kiefte-de Jong, P. Orfanos, C. Bamia, A. Trichopoulou, P. Boffetta, M. Bobak, H. Pikhart, F. Kee, MG. O'Doherty, G. Buckland, J. Woodside, OH. Franco, MA. Ikram, EA. Struijk, A. Pajak, S....
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, Research Support, N.I.H., Extramural, práce podpořená grantem
NLK
Free Medical Journals
od 1999 do Před 1 rokem
Freely Accessible Science Journals
od 1999 do Před 1 rokem
Open Access Digital Library
od 1999-01-01
PubMed
26354545
DOI
10.3945/ajcn.114.095117
Knihovny.cz E-zdroje
- MeSH
- adherence pacienta MeSH
- cholesterol dietní aplikace a dávkování MeSH
- chronická nemoc MeSH
- dieta normy MeSH
- dietní proteiny aplikace a dávkování MeSH
- dietní sacharidy aplikace a dávkování MeSH
- etnicita MeSH
- hodnocení stavu výživy MeSH
- kardiovaskulární nemoci mortalita prevence a kontrola MeSH
- lidé středního věku MeSH
- lidé MeSH
- mastné kyseliny aplikace a dávkování MeSH
- metaanalýza jako téma MeSH
- nenasycené mastné kyseliny MeSH
- ovoce MeSH
- potravní vláknina aplikace a dávkování MeSH
- prospektivní studie MeSH
- senioři MeSH
- Světová zdravotnická organizace MeSH
- výživová politika * MeSH
- zelenina MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Research Support, N.I.H., Extramural MeSH
- Geografické názvy
- Evropa MeSH
- Spojené státy americké MeSH
BACKGROUND: Cardiovascular disease (CVD) represents a leading cause of mortality worldwide, especially in the elderly. Lowering the number of CVD deaths requires preventive strategies targeted on the elderly. OBJECTIVE: The objective was to generate evidence on the association between WHO dietary recommendations and mortality from CVD, coronary artery disease (CAD), and stroke in the elderly aged ≥60 y. DESIGN: We analyzed data from 10 prospective cohort studies from Europe and the United States comprising a total sample of 281,874 men and women free from chronic diseases at baseline. Components of the Healthy Diet Indicator (HDI) included saturated fatty acids, polyunsaturated fatty acids, mono- and disaccharides, protein, cholesterol, dietary fiber, and fruit and vegetables. Cohort-specific HRs adjusted for sex, education, smoking, physical activity, and energy and alcohol intakes were pooled by using a random-effects model. RESULTS: During 3,322,768 person-years of follow-up, 12,492 people died of CVD. An increase of 10 HDI points (complete adherence to an additional WHO guideline) was, on average, not associated with CVD mortality (HR: 0.94; 95% CI: 0.86, 1.03), CAD mortality (HR: 0.99; 95% CI: 0.85, 1.14), or stroke mortality (HR: 0.95; 95% CI: 0.88, 1.03). However, after stratification of the data by geographic region, adherence to the HDI was associated with reduced CVD mortality in the southern European cohorts (HR: 0.87; 95% CI: 0.79, 0.96; I(2) = 0%) and in the US cohort (HR: 0.85; 95% CI: 0.83, 0.87; I(2) = not applicable). CONCLUSION: Overall, greater adherence to the WHO dietary guidelines was not significantly associated with CVD mortality, but the results varied across regions. Clear inverse associations were observed in elderly populations in southern Europe and the United States.
Department of Epidemiology and Population Studies Jagiellonian University Krakow Poland
Department of Epidemiology and Public Health University College London London United Kingdom
Department of Epidemiology Erasmus MC University Medical Centre Rotterdam Netherlands
Department of Epidemiology Julius Centre Utrecht Netherlands
Department of Gastroenterology and Hepatology University Medical Centre Utrecht Netherlands
Department of Public Health and Clinical Medicine Nutritional Research Umeå University Umeå Sweden
Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda MD
Division of Human Nutrition Wageningen University Wageningen Netherlands
Global Public Health Leiden University College the Hague Netherlands
Hellenic Health Foundation Athens Greece
National Institute of Public Health Prague Czech Republic
Novosibirsk State Medical University Novosibirsk Russia
The Tisch Cancer Institute Mount Sinai School of Medicine New York NY
Citace poskytuje Crossref.org
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- $a Jankovic, Nicole $u Division of Human Nutrition, Wageningen University, Wageningen, Netherlands; Centre of Clinical Epidemiology, Institute for Medical Informatics, Biometry and Epidemiology, University Hospital, University Duisburg-Essen, Essen, Germany;
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- $a BACKGROUND: Cardiovascular disease (CVD) represents a leading cause of mortality worldwide, especially in the elderly. Lowering the number of CVD deaths requires preventive strategies targeted on the elderly. OBJECTIVE: The objective was to generate evidence on the association between WHO dietary recommendations and mortality from CVD, coronary artery disease (CAD), and stroke in the elderly aged ≥60 y. DESIGN: We analyzed data from 10 prospective cohort studies from Europe and the United States comprising a total sample of 281,874 men and women free from chronic diseases at baseline. Components of the Healthy Diet Indicator (HDI) included saturated fatty acids, polyunsaturated fatty acids, mono- and disaccharides, protein, cholesterol, dietary fiber, and fruit and vegetables. Cohort-specific HRs adjusted for sex, education, smoking, physical activity, and energy and alcohol intakes were pooled by using a random-effects model. RESULTS: During 3,322,768 person-years of follow-up, 12,492 people died of CVD. An increase of 10 HDI points (complete adherence to an additional WHO guideline) was, on average, not associated with CVD mortality (HR: 0.94; 95% CI: 0.86, 1.03), CAD mortality (HR: 0.99; 95% CI: 0.85, 1.14), or stroke mortality (HR: 0.95; 95% CI: 0.88, 1.03). However, after stratification of the data by geographic region, adherence to the HDI was associated with reduced CVD mortality in the southern European cohorts (HR: 0.87; 95% CI: 0.79, 0.96; I(2) = 0%) and in the US cohort (HR: 0.85; 95% CI: 0.83, 0.87; I(2) = not applicable). CONCLUSION: Overall, greater adherence to the WHO dietary guidelines was not significantly associated with CVD mortality, but the results varied across regions. Clear inverse associations were observed in elderly populations in southern Europe and the United States.
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