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Separation methods in cancer research, real samples

Markéta Vaculovičová, Vojtěch Adam, René Kizek

Language English Country Czech Republic

Document type Review, Research Support, Non-U.S. Gov't

Cancer belongs to the most terrifying diseases. Therefore, diagnostic and therapeutic tools are desperately searched. To detect the disease at it early stage, reliable biomarkers have to be employed, however to identify these molecules and find their connection to the type and stage of the disease is a challenging task. To meet this goal, extremely powerful methods have to be used. Among such methods, mass spectrometry occupies the leading position. However, even such powerful technique needs to be coupled with some kind of separation, which simplifies the complex biological sample prior to the analysis.

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$a Cancer belongs to the most terrifying diseases. Therefore, diagnostic and therapeutic tools are desperately searched. To detect the disease at it early stage, reliable biomarkers have to be employed, however to identify these molecules and find their connection to the type and stage of the disease is a challenging task. To meet this goal, extremely powerful methods have to be used. Among such methods, mass spectrometry occupies the leading position. However, even such powerful technique needs to be coupled with some kind of separation, which simplifies the complex biological sample prior to the analysis.
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$a Adam, Vojtěch, $d 1982- $7 xx0064599 $u Central European Institute of Technology, Brno University of Technology, Czech Republic, European Union
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$a Kizek, René, $d 1972- $7 jn20001005291 $u Central European Institute of Technology, Brno University of Technology, Czech Republic, European Union
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$t Journal of Metallomics and Nanotechnologies $x 2336-3940 $g Roč. 2, č. 2 (2015), s. 44-47 $w MED00185603
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