• Je něco špatně v tomto záznamu ?

Unstable angina pectoris prior to ST elevation myocardial infarction in patients treated with primary percutaneous coronary intervention has no influence on prognosis

K. Kluz, J. Parenica, L. Kubkova, S. Littnerova, J. Tomandl, M. Poloczek, O. Toman, M. Tesak, Z. Cermakova, J. Gottwaldova, J. Manousek, M. Pavkova Goldbergova, J. Spinar, J. Jarkovsky

. 2015 ; 159 (2) : 251-258. [pub] 20140123

Jazyk angličtina Země Česko

Typ dokumentu srovnávací studie, časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc17006077

BACKGROUND: Pre-infarction unstable angina pectoris (UAP) can be considered ischemic preconditioning. The aim of this study was to compare short and long term outcomes in patients with or without pre-infarction UAP and ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). METHODS: 593 patients with STEMI (388 without and 205 with UAP) were evaluated. Levels of biomarkers (troponin I, BNP, NT-ProBNP, neopterin, endoglin and pentraxin-3) at hospital admission and 24 h after STEMI onset were assessed. Echocardiography was undertaken on the fourth day after MI and after 12 months. The median follow-up was 37 months. RESULTS: We found no significant differences in sex, age or risk factors for atherosclerosis between the UAP and non-UAP group. As the median time from the onset of chest pain to admission was significantly longer in the UAP group (228 min vs 258 min; P=0.009), we used a propensity score to obtain comparable matched groups for use in further analyses. The levels of NT-proBNP were significantly higher on admission and after 24 hours in the UAP group. Left ventricular functions according to invasive and echocardiographic parameters were entirely comparable at hospitalization and after 12 months. No differences were found in severity index of acute heart failure during hospitalization. The incidence of major acute coronary events during follow-up was comparable for the groups. CONCLUSIONS: In patients with STEMI treated with primary PCI, pre-infarction UAP has no beneficial clinical effect during hospitalization or during long-term follow-up.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc17006077
003      
CZ-PrNML
005      
20200720084536.0
007      
ta
008      
170210s2015 xr d f 000 0|eng||
009      
AR
024    7_
$a 10.5507/bp.2014.003 $2 doi
035    __
$a (PubMed)24457834
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Kluz, Krystyna $u Department of Internal Cardiology, Medical Faculty, Masaryk University, Brno, Czech Republic; Hospital Podlesi a.s., Trinec $7 xx0243485
245    10
$a Unstable angina pectoris prior to ST elevation myocardial infarction in patients treated with primary percutaneous coronary intervention has no influence on prognosis / $c K. Kluz, J. Parenica, L. Kubkova, S. Littnerova, J. Tomandl, M. Poloczek, O. Toman, M. Tesak, Z. Cermakova, J. Gottwaldova, J. Manousek, M. Pavkova Goldbergova, J. Spinar, J. Jarkovsky
520    9_
$a BACKGROUND: Pre-infarction unstable angina pectoris (UAP) can be considered ischemic preconditioning. The aim of this study was to compare short and long term outcomes in patients with or without pre-infarction UAP and ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). METHODS: 593 patients with STEMI (388 without and 205 with UAP) were evaluated. Levels of biomarkers (troponin I, BNP, NT-ProBNP, neopterin, endoglin and pentraxin-3) at hospital admission and 24 h after STEMI onset were assessed. Echocardiography was undertaken on the fourth day after MI and after 12 months. The median follow-up was 37 months. RESULTS: We found no significant differences in sex, age or risk factors for atherosclerosis between the UAP and non-UAP group. As the median time from the onset of chest pain to admission was significantly longer in the UAP group (228 min vs 258 min; P=0.009), we used a propensity score to obtain comparable matched groups for use in further analyses. The levels of NT-proBNP were significantly higher on admission and after 24 hours in the UAP group. Left ventricular functions according to invasive and echocardiographic parameters were entirely comparable at hospitalization and after 12 months. No differences were found in severity index of acute heart failure during hospitalization. The incidence of major acute coronary events during follow-up was comparable for the groups. CONCLUSIONS: In patients with STEMI treated with primary PCI, pre-infarction UAP has no beneficial clinical effect during hospitalization or during long-term follow-up.
650    _2
$a dospělí $7 D000328
650    _2
$a senioři $7 D000368
650    _2
$a nestabilní angina pectoris $x komplikace $x mortalita $7 D000789
650    _2
$a biologické markery $x metabolismus $7 D015415
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a následné studie $7 D005500
650    _2
$a srdeční selhání $x etiologie $7 D006333
650    _2
$a lidé $7 D006801
650    _2
$a Kaplanův-Meierův odhad $7 D053208
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé středního věku $7 D008875
650    _2
$a infarkt myokardu $x mortalita $x chirurgie $7 D009203
650    _2
$a natriuretický peptid typu B $x metabolismus $7 D020097
650    _2
$a peptidové fragmenty $x metabolismus $7 D010446
650    12
$a koronární angioplastika $7 D062645
650    _2
$a prognóza $7 D011379
650    _2
$a prospektivní studie $7 D011446
650    _2
$a recidiva $7 D012008
650    _2
$a cévní mozková příhoda $x etiologie $7 D020521
650    _2
$a čas zasáhnout při rozvinutí nemoci $7 D061665
655    _2
$a srovnávací studie $7 D003160
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Pařenica, Jiří $u Department of Cardiology, Faculty Hospital Brno; Department of Cardiovascular Disease, International Clinical Research Center, St. Anne´s University Hospital in Brno $7 xx0101388
700    1_
$a Kubková, Lenka $u Department of Internal Cardiology, Medical Faculty, Masaryk University, Brno, Czech Republic; Department of Cardiology, Faculty Hospital Brno; Department of Cardiovascular Disease, International Clinical Research Center, St. Anne´s University Hospital in Brno $7 xx0241832
700    1_
$a Littnerová, Simona $u Institute of Biostatistics and Analyses, Masaryk University, Brno $7 jo2012694303
700    1_
$a Tomandl, Josef, $u Department of Internal Cardiology, Medical Faculty, Masaryk University, Brno, Czech Republic $d 1964- $7 mzk2003175507
700    1_
$a Poloczek, Martin $u Department of Cardiology, Faculty Hospital Brno $7 xx0101387
700    1_
$a Toman, Ondřej, $u Department of Cardiology, Faculty Hospital Brno $d 1974- $7 xx0082234
700    1_
$a Tesák, Martin $u Department of Cardiology, Faculty Hospital Brno. Hospital Trebic, Trebic-Jejkov $7 xx0104172
700    1_
$a Čermáková, Zdeňka $u Department of Biochemistry, Faculty Hospital Brno $7 xx0084249
700    1_
$a Gottwaldová, Jana $u Department of Biochemistry, Faculty Hospital Brno $7 _BN006903
700    1_
$a Manoušek, Jiří $u Department of Cardiology, Faculty Hospital Brno $7 _BN004708
700    1_
$a Pávková Goldbergová, Monika $u Department of Internal Cardiology, Medical Faculty, Masaryk University, Brno, Czech Republic $7 xx0054290
700    1_
$a Špinar, Jindřich, $u Department of Internal Cardiology, Medical Faculty, Masaryk University, Brno, Czech Republic; Department of Cardiology, Faculty Hospital Brno; Department of Cardiovascular Disease, International Clinical Research Center, St. Anne´s University Hospital in Brno $d 1960- $7 nlk20030128322
700    1_
$a Jarkovský, Jiří $u Institute of Biostatistics and Analyses, Masaryk University, Brno $7 stk2008461294
773    0_
$w MED00012606 $t Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czech Republic $x 1213-8118 $g Roč. 159, č. 2 (2015), s. 251-258
910    __
$a ABA008 $b A 1502 $c 958 $y 4 $z 0
990    __
$a 20170210 $b ABA008
991    __
$a 20200720084537 $b ABA008
999    __
$a ok $b bmc $g 1192602 $s 966724
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2015 $b 159 $c 2 $d 251-258 $e 20140123 $i 1213-8118 $m Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic $n Biomed. Pap. Fac. Med. Palacký Univ. Olomouc Czech Repub. (Print) $x MED00012606
LZP    __
$b NLK118 $a Pubmed-20170210

Najít záznam

Citační ukazatele

Možnosti archivace