Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Use of the Crustacean Artemia franciscana for alternative biotests

Petr Dvořák, Katarína Beňová, Michal Žďárský, Zbyněk Sklenář, Alena Havelková

. 2010 ; 79 (Supplementum 9) : 47-53.

Jazyk angličtina Země Česko

Typ dokumentu práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc17027485

Use of the crustacean Artemia franciscana for alternative biotests of the second generation was studied, and possible experimental design and applications of such tests outlined. In addition to the classical use in ecotoxicology, the test can be used in pharmacology as well, or to monitor the effects of ionizing radiation in co-exposure with some chemical compounds. The synergistic effect of co-exposure of PCB (DELOR 103), cadmium chloride and potassium dichromate with beta 89Sr irradiation was shown. We also demonstrated the anti-oxidative and pro-oxidative effects of the ascorbic acid in dependence on its concentration. Use of the pharmaco-toxicological screening in search for the novel inhibitors of cyclin-dependent kinases was demonstrated as well, showing that Artemia franciscana may be used as a suitable biosensor instead of the expensive tests on higher vertebrates.

Citace poskytuje Crossref.org

Bibliografie atd.

Literatura

000      
00000naa a2200000 a 4500
001      
bmc17027485
003      
CZ-PrNML
005      
20190128145924.0
007      
cr|cn|
008      
170913s2010 xr d fs 000 0|eng||
009      
AR
024    7_
$a 10.2754/avb201079S9S047 $2 doi
040    __
$a ABA008 $d ABA008 $e AACR2 $b cze
041    0_
$a eng
044    __
$a xr
100    1_
$a Dvořák, Petr $7 mzk2005318109 $u Department of Biochemistry, Chemistry and Biophysics, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic
245    10
$a Use of the Crustacean Artemia franciscana for alternative biotests / $c Petr Dvořák, Katarína Beňová, Michal Žďárský, Zbyněk Sklenář, Alena Havelková
504    __
$a Literatura
520    3_
$a Use of the crustacean Artemia franciscana for alternative biotests of the second generation was studied, and possible experimental design and applications of such tests outlined. In addition to the classical use in ecotoxicology, the test can be used in pharmacology as well, or to monitor the effects of ionizing radiation in co-exposure with some chemical compounds. The synergistic effect of co-exposure of PCB (DELOR 103), cadmium chloride and potassium dichromate with beta 89Sr irradiation was shown. We also demonstrated the anti-oxidative and pro-oxidative effects of the ascorbic acid in dependence on its concentration. Use of the pharmaco-toxicological screening in search for the novel inhibitors of cyclin-dependent kinases was demonstrated as well, showing that Artemia franciscana may be used as a suitable biosensor instead of the expensive tests on higher vertebrates.
650    _2
$a zvířata $7 D000818
650    12
$a Artemia $7 D001156
650    _2
$a kyselina askorbová $x aplikace a dávkování $x farmakologie $7 D001205
650    _2
$a inhibiční proteiny cyklin-dependentních kinas $x toxicita $7 D050756
650    12
$a testy toxicity $7 D018675
650    _2
$a radioizotopy stroncia $x toxicita $7 D013326
650    _2
$a chlorid kademnatý $x toxicita $7 D019256
650    _2
$a dvojchroman draselný $x toxicita $7 D011192
650    _2
$a ionizující záření $7 D011839
650    _2
$a peroxid vodíku $7 D006861
653    00
$a DELOR 103
653    00
$a letalita
653    00
$a synergický efekt
653    10
$a biotesty
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Beňová, Katarína $7 xx0126059 $u Department of Biology and Genetics, University of Veterinary Medicine Košice, Slovak Republic
700    1_
$a Žďárský, Michal $7 jo2013796032 $u Department of Biochemistry, Chemistry and Biophysics, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic
700    1_
$a Sklenář, Zbyněk, $d 1979- $7 mzk2009512699 $u Department of Biochemistry, Chemistry and Biophysics, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic
700    1_
$a Havelková, Alena $7 mub2012732593 $u Department of Physioterapy, Faculty of Medicine, Masaryk University, Brno, Czech Republic
773    0_
$t Acta veterinaria Brno $x 0001-7213 $g Roč. 79, Supplementum 9 (2010), s. 47-53 $w MED00172332
856    41
$u https://actavet.vfu.cz/ $y domovská stránka časopisu
910    __
$a ABA008 $b online $y 4 $z 0
990    __
$a 20170908071734 $b ABA008
991    __
$a 20190128150152 $b ABA008
999    __
$a ok $b bmc $g 1247454 $s 988480
BAS    __
$a 3 $a 4
BMC    __
$a 2010 $b 79 $c Supplementum 9 $d 47-53 $i 0001-7213 $m Acta veterinaria Brno $x MED00172332
LZP    __
$c NLK185 $d 20190128 $a NLK 2017-11/pk

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé

Možnosti archivace