Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Ethnopharmacological Approaches for Therapy of Jaundice: Part II. Highly Used Plant Species from Acanthaceae, Euphorbiaceae, Asteraceae, Combretaceae, and Fabaceae Families

D. Tewari, A. Mocan, ED. Parvanov, AN. Sah, SM. Nabavi, L. Huminiecki, ZF. Ma, YY. Lee, JO. Horbańczuk, AG. Atanasov,

. 2017 ; 8 (-) : 519. [pub] 20170810

Language English Country Switzerland

Document type Journal Article, Review

Persistent link   https://www.medvik.cz/link/bmc17031970

In many developing countries, jaundice is the common symptom of hepatic diseases which are a major cause of mortality. The use of natural product-based therapies is very popular for such hepatic disorders. A great number of medicinal plants have been utilized for this purpose and some facilitated the discovery of active compounds which helped the development of new synthetic drugs against jaundice. However, more epidemiological studies and clinical trials are required for the practical implementation of the plant pharmacotherapy of jaundice. The focus of this second part of our review is on several of the most prominent plants used against jaundice identified in the analysis performed in the first part of the review viz. Andrographis paniculata (Burm.f.) Nees, Silybum marianum (L.) Gaertn., Terminalia chebula Retz., Glycyrrhiza glabra L. and some species of genus Phyllanthus. Furthermore, we discuss their physiological effects, biologically active ingredients, and the potential mechanisms of action. Some of the most important active ingredients were silybin (also recommended by German commission), phyllanthin and andrographolide, whose action leads to bilirubin reduction and normalization of the levels of relevant serum enzymes indicative for the pathophysiological status of the liver.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc17031970
003      
CZ-PrNML
005      
20171030122825.0
007      
ta
008      
171025s2017 sz f 000 0|eng||
009      
AR
024    7_
$a 10.3389/fphar.2017.00519 $2 doi
035    __
$a (PubMed)28848436
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sz
100    1_
$a Tewari, Devesh $u Department of Pharmaceutical Sciences, Faculty of Technology, Kumaun UniversityNainital, India.
245    10
$a Ethnopharmacological Approaches for Therapy of Jaundice: Part II. Highly Used Plant Species from Acanthaceae, Euphorbiaceae, Asteraceae, Combretaceae, and Fabaceae Families / $c D. Tewari, A. Mocan, ED. Parvanov, AN. Sah, SM. Nabavi, L. Huminiecki, ZF. Ma, YY. Lee, JO. Horbańczuk, AG. Atanasov,
520    9_
$a In many developing countries, jaundice is the common symptom of hepatic diseases which are a major cause of mortality. The use of natural product-based therapies is very popular for such hepatic disorders. A great number of medicinal plants have been utilized for this purpose and some facilitated the discovery of active compounds which helped the development of new synthetic drugs against jaundice. However, more epidemiological studies and clinical trials are required for the practical implementation of the plant pharmacotherapy of jaundice. The focus of this second part of our review is on several of the most prominent plants used against jaundice identified in the analysis performed in the first part of the review viz. Andrographis paniculata (Burm.f.) Nees, Silybum marianum (L.) Gaertn., Terminalia chebula Retz., Glycyrrhiza glabra L. and some species of genus Phyllanthus. Furthermore, we discuss their physiological effects, biologically active ingredients, and the potential mechanisms of action. Some of the most important active ingredients were silybin (also recommended by German commission), phyllanthin and andrographolide, whose action leads to bilirubin reduction and normalization of the levels of relevant serum enzymes indicative for the pathophysiological status of the liver.
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Mocan, Andrei $u Department of Pharmaceutical Botany, "Iuliu Haţieganu" University of Medicine and PharmacyCluj-Napoca, Romania. ICHAT and Institute for Life Sciences, University of Agricultural Sciences and Veterinary MedicineCluj-Napoca, Romania.
700    1_
$a Parvanov, Emil D $u Division BIOCEV, Institute of Molecular Genetics, Academy of Sciences of the Czech RepublicPrague, Czechia.
700    1_
$a Sah, Archana N $u Department of Pharmaceutical Sciences, Faculty of Technology, Kumaun UniversityNainital, India.
700    1_
$a Nabavi, Seyed M $u Applied Biotechnology Research Center, Baqiyatallah University of Medical SciencesTehran, Iran.
700    1_
$a Huminiecki, Lukasz $u Institute of Genetics and Animal Breeding of the Polish Academy of SciencesJastrzebiec, Poland.
700    1_
$a Ma, Zheng Feei $u School of Medical Sciences, Universiti Sains MalaysiaKota Bharu, Malaysia. Department of Public Health, Xi'an Jiaotong-Liverpool UniversitySuzhou, China.
700    1_
$a Lee, Yeong Yeh $u School of Medical Sciences, Universiti Sains MalaysiaKota Bharu, Malaysia.
700    1_
$a Horbańczuk, Jarosław O $u Institute of Genetics and Animal Breeding of the Polish Academy of SciencesJastrzebiec, Poland.
700    1_
$a Atanasov, Atanas G $u Institute of Genetics and Animal Breeding of the Polish Academy of SciencesJastrzebiec, Poland. Department of Pharmacognosy, University of ViennaVienna, Austria. Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of ViennaVienna, Austria. $7 gn_A_00009691
773    0_
$w MED00174597 $t Frontiers in pharmacology $x 1663-9812 $g Roč. 8, č. - (2017), s. 519
856    41
$u https://pubmed.ncbi.nlm.nih.gov/28848436 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20171025 $b ABA008
991    __
$a 20171030122914 $b ABA008
999    __
$a ind $b bmc $g 1255563 $s 992997
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2017 $b 8 $c - $d 519 $e 20170810 $i 1663-9812 $m Frontiers in pharmacology $n Front Pharmacol $x MED00174597
LZP    __
$a Pubmed-20171025

Find record

Citation metrics

Archiving options