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Copy-number variation of housekeeping gene rpl13a in rat strains selected for nervous system excitability
R. Kalendar, A. Belyayev, T. Zachepilo, A. Vaido, D. Maidanyuk, AH. Schulman, N. Dyuzhikova,
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články
- MeSH
- hipokampus metabolismus fyziologie MeSH
- kortikální excitabilita genetika fyziologie MeSH
- kostní dřeň metabolismus fyziologie MeSH
- krysa rodu rattus MeSH
- nervový systém - fyziologické jevy genetika MeSH
- ribozomální proteiny genetika MeSH
- variabilita počtu kopií segmentů DNA genetika MeSH
- zvířata MeSH
- Check Tag
- krysa rodu rattus MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
We evaluated copy number variation (CNV) for four genes in rat strains differing in nervous system excitability. rpl13a copy number is significantly reduced in hippocampus and bone marrow in rats with a high excitability threshold and stress. The observed phenomenon may be associated with a role for rpl13a in lipid metabolism.
Citace poskytuje Crossref.org
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- $a Kalendar, Ruslan $u LUKE/BI Plant Genome Dynamics, Institute of Biotechnology and Viikki Plant Science Centre, University of Helsinki, P.O. Box 65, FI-00014 Helsinki, Finland. Electronic address: ruslan.kalendar@mail.ru.
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- $a Belyayev, Alexander $u Laboratory of Molecular Cytogenetics and Karyology, Institute of Botany, Czech Academy of Sciences, Zámek 1, CZ-25243 Průhonice, Czech Republic. Electronic address: alexander.belyayev@ibot.cas.cz.
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- $a Zachepilo, Tatiana $u Laboratory of Genetics of Higher Nervous Activity, Pavlov Institute of Physiology of the Russian Academy of Science, Nab. Makarova, 6, 199034 Saint Petersburg, Russia. Electronic address: polosataya2@mail.ru.
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- $a Vaido, Alexander $u Laboratory of Genetics of Higher Nervous Activity, Pavlov Institute of Physiology of the Russian Academy of Science, Nab. Makarova, 6, 199034 Saint Petersburg, Russia. Electronic address: aivaido@mail.ru.
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- $a Maidanyuk, Dmitry $u Laboratory of Genomic and Proteomic Research, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia. Electronic address: DMaidaniuk@kantiana.ru.
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- $a Schulman, Alan H $u LUKE/BI Plant Genome Dynamics, Institute of Biotechnology and Viikki Plant Science Centre, University of Helsinki, P.O. Box 65, FI-00014 Helsinki, Finland; Green Technology, Natural Resources Institute Finland (Luke), Latokartanonkaari 9, FI-00790 Helsinki, Finland. Electronic address: alan.schulman@helsinki.fi.
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- $a Dyuzhikova, Natalia $u Laboratory of Genetics of Higher Nervous Activity, Pavlov Institute of Physiology of the Russian Academy of Science, Nab. Makarova, 6, 199034 Saint Petersburg, Russia. Electronic address: dyuzhikova@mail.ru.
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