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Copy-number variation of housekeeping gene rpl13a in rat strains selected for nervous system excitability

R. Kalendar, A. Belyayev, T. Zachepilo, A. Vaido, D. Maidanyuk, AH. Schulman, N. Dyuzhikova,

. 2017 ; 33 (-) : 11-15. [pub] 20170210

Jazyk angličtina Země Velká Británie

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc18010802

We evaluated copy number variation (CNV) for four genes in rat strains differing in nervous system excitability. rpl13a copy number is significantly reduced in hippocampus and bone marrow in rats with a high excitability threshold and stress. The observed phenomenon may be associated with a role for rpl13a in lipid metabolism.

Citace poskytuje Crossref.org

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$a Belyayev, Alexander $u Laboratory of Molecular Cytogenetics and Karyology, Institute of Botany, Czech Academy of Sciences, Zámek 1, CZ-25243 Průhonice, Czech Republic. Electronic address: alexander.belyayev@ibot.cas.cz.
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$a Zachepilo, Tatiana $u Laboratory of Genetics of Higher Nervous Activity, Pavlov Institute of Physiology of the Russian Academy of Science, Nab. Makarova, 6, 199034 Saint Petersburg, Russia. Electronic address: polosataya2@mail.ru.
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$a Vaido, Alexander $u Laboratory of Genetics of Higher Nervous Activity, Pavlov Institute of Physiology of the Russian Academy of Science, Nab. Makarova, 6, 199034 Saint Petersburg, Russia. Electronic address: aivaido@mail.ru.
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$a Maidanyuk, Dmitry $u Laboratory of Genomic and Proteomic Research, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia. Electronic address: DMaidaniuk@kantiana.ru.
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$a Schulman, Alan H $u LUKE/BI Plant Genome Dynamics, Institute of Biotechnology and Viikki Plant Science Centre, University of Helsinki, P.O. Box 65, FI-00014 Helsinki, Finland; Green Technology, Natural Resources Institute Finland (Luke), Latokartanonkaari 9, FI-00790 Helsinki, Finland. Electronic address: alan.schulman@helsinki.fi.
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$a Dyuzhikova, Natalia $u Laboratory of Genetics of Higher Nervous Activity, Pavlov Institute of Physiology of the Russian Academy of Science, Nab. Makarova, 6, 199034 Saint Petersburg, Russia. Electronic address: dyuzhikova@mail.ru.
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