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Copy-number variation of housekeeping gene rpl13a in rat strains selected for nervous system excitability
R. Kalendar, A. Belyayev, T. Zachepilo, A. Vaido, D. Maidanyuk, AH. Schulman, N. Dyuzhikova,
Molecular and cellular probes.
2017 ;
33 (-) :
11-15.
[pub] 20170210
Language English Country Great Britain
Document type Journal Article
Persistent link
https://www.medvik.cz/link/bmc18010802
- MeSH
- Hippocampus metabolism physiology MeSH
- Cortical Excitability genetics physiology MeSH
- Bone Marrow metabolism physiology MeSH
- Rats MeSH
- Nervous System Physiological Phenomena genetics MeSH
- Ribosomal Proteins genetics MeSH
- DNA Copy Number Variations genetics MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
We evaluated copy number variation (CNV) for four genes in rat strains differing in nervous system excitability. rpl13a copy number is significantly reduced in hippocampus and bone marrow in rats with a high excitability threshold and stress. The observed phenomenon may be associated with a role for rpl13a in lipid metabolism.
References provided by Crossref.org
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- $a Zachepilo, Tatiana $u Laboratory of Genetics of Higher Nervous Activity, Pavlov Institute of Physiology of the Russian Academy of Science, Nab. Makarova, 6, 199034 Saint Petersburg, Russia. Electronic address: polosataya2@mail.ru.
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- $a Dyuzhikova, Natalia $u Laboratory of Genetics of Higher Nervous Activity, Pavlov Institute of Physiology of the Russian Academy of Science, Nab. Makarova, 6, 199034 Saint Petersburg, Russia. Electronic address: dyuzhikova@mail.ru.
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