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Antifungal effects of the biological agent Pythium oligandrum observed in vitro
M. Načeradská, M. Fridrichová, D. Kellnerová, S. Peková, P. Lány,
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články
NLK
PubMed Central
od 1999
ROAD: Directory of Open Access Scholarly Resources
od 1999
PubMed
27418287
DOI
10.1177/1098612x16658690
Knihovny.cz E-zdroje
- MeSH
- antifungální látky farmakologie MeSH
- kočky MeSH
- Microsporum účinky léků MeSH
- nemoci koček farmakoterapie mikrobiologie MeSH
- parazitické testy citlivosti veterinární MeSH
- Pythium * MeSH
- tinea farmakoterapie mikrobiologie veterinární MeSH
- Trichophyton účinky léků MeSH
- vlasy, chlupy mikrobiologie MeSH
- výsledek terapie MeSH
- zvířata MeSH
- Check Tag
- kočky MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
Objectives Dermatophytosis, commonly known as ringworm, is a superficial fungal skin disease and zoonosis. Pythium oligandrum is a micromycete with mycoparasitic properties that is used in agriculture to control fungal infections on plants. Formulations containing P oligandrum were also developed for the treatment of dermatophytoses, but only a small number of case studies have been published. In order to document the process in simplified conditions in vitro, we investigated the effectiveness of P oligandrum against three pathogenic dermatophytes common in domestic animals. Methods Cultures of the pathogens grown on nutrient media and experimentally infected cat hair were treated with P oligandrum preparations in therapeutic concentration and the changes were documented by microscopic videos and scanning electron microscopy. Results There was strong mycoparasitic activity of P oligandrum against Microsporum canis, Microsporum gypseum and Trichophyton mentagrophytes. Conclusions and relevance P oligandrum was demonstrated to be effective against three common causes of dermatophytosis in vitro.
Institute of Geology Academy of Sciences Prague Czech Republic
Sevaron Diagnostic Laboratory Brno Czech Republic
Vemodia Laboratory for Veterinary Molecular Diagnostics Prague Czech Republic
Citace poskytuje Crossref.org
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- $a Objectives Dermatophytosis, commonly known as ringworm, is a superficial fungal skin disease and zoonosis. Pythium oligandrum is a micromycete with mycoparasitic properties that is used in agriculture to control fungal infections on plants. Formulations containing P oligandrum were also developed for the treatment of dermatophytoses, but only a small number of case studies have been published. In order to document the process in simplified conditions in vitro, we investigated the effectiveness of P oligandrum against three pathogenic dermatophytes common in domestic animals. Methods Cultures of the pathogens grown on nutrient media and experimentally infected cat hair were treated with P oligandrum preparations in therapeutic concentration and the changes were documented by microscopic videos and scanning electron microscopy. Results There was strong mycoparasitic activity of P oligandrum against Microsporum canis, Microsporum gypseum and Trichophyton mentagrophytes. Conclusions and relevance P oligandrum was demonstrated to be effective against three common causes of dermatophytosis in vitro.
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