• Je něco špatně v tomto záznamu ?

Some quantitative EEG features in default mode resting state network under general anaesthesia

P. Jombík, M. Drobny, B. Saniova, M. Fischer, P. Kaderjaková, M. Lajčiaková, E. Bakosova, E. Drobna, P. Bob, V. Nosáľ,

. 2017 ; 38 (4) : 261-268.

Jazyk angličtina Země Švédsko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc18024680

OBJECTIVES: The default mode resting state network (DMRSN) constitutes a circuit which is active in conditions when the subject is at rest. We tested the hypothesis that its function will be altered during unconsciousness. METHODS: Changes in the mean squared coherences in five conventional frequency bands (delta to gamma) in DMRSN during general anaesthesia (GA) were investigated in 39 patients. They were compared with the normal EEG of 86 alert subjects, severely abnormal EEG of 112 patients with dementia and/or encephalopathy, and the mathematical model of brain death. RESULTS: Anaesthetised patients showed significant decrease in the gamma coherence in the posterior area of the DMRSN compared to both the control group and the patients with dementia and/or encephalopathy. Among the anaesthetized patients 21 had a clear burst suppression pattern with prolonged epochs of suppression in EEG. In suppressed EEG segment the differences between the connections of the anterior to posterior parts and connections between the posterior parts of the DMRSN were almost lost. However, they still showed highly significant differences in most items when compared with coherences in the mathematical model of brain death. CONCLUSION: The functional connectivity in the DMRSN could be a reliable and robust method for assessing the depth of anaesthesia and maybe also disorders of consciousness in general. The mean squared coherences in the gamma frequency band indicated the highest sensitivity for the depth of unconsciousness. The measure is not dependent on the diffused slowing in dementia or encephalopathy patients as long as they remain in a full consciousness.

000      
00000naa a2200000 a 4500
001      
bmc18024680
003      
CZ-PrNML
005      
20240618121527.0
007      
ta
008      
180709s2017 sw f 000 0|eng||
009      
AR
035    __
$a (PubMed)28871712
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sw
100    1_
$a Jombík, Peter $u Department of Neurology, Hospital Zvolen, Slovakia.
245    10
$a Some quantitative EEG features in default mode resting state network under general anaesthesia / $c P. Jombík, M. Drobny, B. Saniova, M. Fischer, P. Kaderjaková, M. Lajčiaková, E. Bakosova, E. Drobna, P. Bob, V. Nosáľ,
520    9_
$a OBJECTIVES: The default mode resting state network (DMRSN) constitutes a circuit which is active in conditions when the subject is at rest. We tested the hypothesis that its function will be altered during unconsciousness. METHODS: Changes in the mean squared coherences in five conventional frequency bands (delta to gamma) in DMRSN during general anaesthesia (GA) were investigated in 39 patients. They were compared with the normal EEG of 86 alert subjects, severely abnormal EEG of 112 patients with dementia and/or encephalopathy, and the mathematical model of brain death. RESULTS: Anaesthetised patients showed significant decrease in the gamma coherence in the posterior area of the DMRSN compared to both the control group and the patients with dementia and/or encephalopathy. Among the anaesthetized patients 21 had a clear burst suppression pattern with prolonged epochs of suppression in EEG. In suppressed EEG segment the differences between the connections of the anterior to posterior parts and connections between the posterior parts of the DMRSN were almost lost. However, they still showed highly significant differences in most items when compared with coherences in the mathematical model of brain death. CONCLUSION: The functional connectivity in the DMRSN could be a reliable and robust method for assessing the depth of anaesthesia and maybe also disorders of consciousness in general. The mean squared coherences in the gamma frequency band indicated the highest sensitivity for the depth of unconsciousness. The measure is not dependent on the diffused slowing in dementia or encephalopathy patients as long as they remain in a full consciousness.
650    _2
$a mladiství $7 D000293
650    _2
$a dospělí $7 D000328
650    _2
$a senioři $7 D000368
650    _2
$a alfa rytmus EEG $x fyziologie $7 D000513
650    12
$a celková anestezie $7 D000768
650    _2
$a mozek $x patofyziologie $7 D001921
650    _2
$a mapování mozku $x metody $7 D001931
650    _2
$a dítě $7 D002648
650    _2
$a delta rytmus EEG $x fyziologie $7 D003700
650    _2
$a elektroencefalografie $7 D004569
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé středního věku $7 D008875
650    _2
$a nervová síť $x patofyziologie $7 D009415
650    _2
$a nervové dráhy $x patofyziologie $7 D009434
650    _2
$a odpočinek $x fyziologie $7 D012146
650    _2
$a bezvědomí $x patofyziologie $7 D014474
650    _2
$a mladý dospělý $7 D055815
655    _2
$a časopisecké články $7 D016428
700    1_
$a Drobny, Michal $u Clinic of Anaesthesiology and Intensive Care Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine and Martin University Hospital, Martin, Slovakia.
700    1_
$a Saniova, Beata $u Clinic of Anaesthesiology and Intensive Care Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine and Martin University Hospital, Martin, Slovakia.
700    1_
$a Fischer, Martin $u Clinic of Anaesthesiology and Intensive Care Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine and Martin University Hospital, Martin, Slovakia.
700    1_
$a Kaderjaková, Petra $u Department of Neurology, Hospital Zvolen, Slovakia.
700    1_
$a Lajčiaková, Marianna $u Clinic of Anaesthesiology and Intensive Care Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine and Martin University Hospital, Martin, Slovakia.
700    1_
$a Bakosova, Erika $u Clinic of Anaesthesiology and Intensive Care Medicine, Comenius University in Bratislava, Jessenius Faculty of Medicine and Martin University Hospital, Martin, Slovakia.
700    1_
$a Drobná, Eva, $d 1960- $u Armed Forces Academy of General MR Stefanik in Liptovsky Mikulas, Slovakia. $7 xx0307114
700    1_
$a Bob, Petr $u Centre for Neuropsychiatric Research of Traumatic Stress, and Department of Psychiatry, 1st Faculty of Medicine, Charles University, Prague, Czech Republic.
700    1_
$a Nosáľ, Vladimír $u Clinic of Neurology, Comenius University in Bratislava, Jessenius Faculty of Medicine and University Hospital in Martin, Slovakia.
773    0_
$w MED00168352 $t Neuro-endocrinology letters $x 0172-780X $g Roč. 38, č. 4 (2017), s. 261-268
856    41
$u https://pubmed.ncbi.nlm.nih.gov/28871712 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20180709 $b ABA008
991    __
$a 20240618121528 $b ABA008
999    __
$a ok $b bmc $g 1316811 $s 1021601
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2017 $b 38 $c 4 $d 261-268 $i 0172-780X $m Neuro-endocrinology letters $n Neuro-endocrinol. lett. $x MED00168352
LZP    __
$a Pubmed-20180709

Najít záznam

Citační ukazatele

Nahrávání dat ...

Možnosti archivace

Nahrávání dat ...