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Fertility preservation issues in pediatric hematopoietic stem cell transplantation: practical approaches from the consensus of the Pediatric Diseases Working Party of the EBMT and the International BFM Study Group
A. Balduzzi, JH. Dalle, K. Jahnukainen, M. von Wolff, G. Lucchini, M. Ifversen, KT. Macklon, C. Poirot, T. Diesch, A. Jarisch, D. Bresters, I. Yaniv, B. Gibson, AM. Willasch, R. Fadini, L. Ferrari, A. Lawitschka, A. Ahler, N. Sänger, S....
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, multicentrická studie
NLK
Free Medical Journals
od 1997 do Před 1 rokem
Freely Accessible Science Journals
od 1997 do Před 1 rokem
ProQuest Central
od 2000-01-01 do Před 1 rokem
Open Access Digital Library
od 1997-01-01
Health & Medicine (ProQuest)
od 2000-01-01 do Před 1 rokem
PubMed
28737775
DOI
10.1038/bmt.2017.147
Knihovny.cz E-zdroje
- MeSH
- alografty MeSH
- dítě MeSH
- konsensus * MeSH
- kryoprezervace metody MeSH
- lidé MeSH
- mladiství MeSH
- ovarium * MeSH
- protinádorové látky škodlivé účinky terapeutické užití MeSH
- směrnice pro lékařskou praxi jako téma MeSH
- testis * MeSH
- transplantace hematopoetických kmenových buněk * MeSH
- zachování plodnosti metody MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
Fertility preservation is an urgent challenge in the transplant setting. A panel of transplanters and fertility specialists within the Pediatric Diseases Working Party of the European Society for Blood and Marrow Transplantation (EBMT) and the International BFM Study Group provides specific guidelines. Patients and families should be informed of possible gender- and age-specific cryopreservation strategies that should be tailored according to the underlying disease, clinical condition and previous exposure to chemotherapy. Semen collection should be routinely offered to all postpubertal boys at the diagnosis of any disease requiring therapy that could potentially impair fertility. Testicular tissue collection might be offered to postpubertal boys; nevertheless, its use has been unsuccessful to date. Oocyte collection after hormonal hyperstimulation should be offered to postpubertal girls facing gonadotoxic therapies that could be delayed for the 2 weeks required for the procedure. Ovarian tissue collection could be offered to pre-/post-pubertal girls. Pregnancies have been reported after postpubertal ovarian tissue reimplantation; however, to date, no pregnancy has been reported after the reimplantation of prepubertal ovarian tissue or in vitro maturation of pre-/post-pubertal ovarian tissue. Possible future advances in reproductive medicine could change this scenario. Health authorities should prioritize fertility preservation projects in pediatric transplantation to improve patient care and quality of life.
Bone Marrow Transplant Department Great Ormond Street Hospital London UK
Centro di Medicina della Riproduzione Biogenesi Istituti Clinici Zucchi Monza Italy
Department of Gynecology and Obstetrics Ospedale San Gerardo di Monza Monza Italy
Department of Paediatric Haematology Royal Hospital for Children Scotland UK
Department of Pediatric Hematology and Oncology University Hospital Motol Prague Czech Republic
EBMT Paris Office Hospital Saint Antoine Paris France
Hemato Immunology Department Robert Debre Hospital APHP and Paris Diderot University Paris France
Pediatric Oncology and Hematology Department Hospital Universitario Vall d'Hebron Barcelona Spain
St Anna Children's Hospital UKKJ MUW Vienna Austria
The Fertility Clinic Copenhagen University Hospital Copenhagen Denmark
Willem Alexander Children's Hospital Leiden University Medical Center Leiden The Netherlands
Citace poskytuje Crossref.org
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