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Energy, Protein, Carbohydrate, and Lipid Intakes and Their Effects on Morbidity and Mortality in Critically Ill Adult Patients: A Systematic Review
A. Patkova, V. Joskova, E. Havel, M. Kovarik, M. Kucharova, Z. Zadak, M. Hronek,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, přehledy
NLK
Free Medical Journals
od 2010 do Před 1 rokem
PubMed Central
od 2010
Europe PubMed Central
od 2010 do Před 1 rokem
Open Access Digital Library
od 2010-11-01
ROAD: Directory of Open Access Scholarly Resources
od 2010
PubMed
28710148
DOI
10.3945/an.117.015172
Knihovny.cz E-zdroje
- MeSH
- dietní proteiny aplikace a dávkování MeSH
- dietní sacharidy aplikace a dávkování MeSH
- dietní tuky aplikace a dávkování MeSH
- dospělí MeSH
- energetický metabolismus MeSH
- energetický příjem * MeSH
- enterální výživa MeSH
- inzulin krev MeSH
- jednotky intenzivní péče MeSH
- krevní glukóza metabolismus MeSH
- kritický stav epidemiologie terapie MeSH
- lidé MeSH
- metaanalýza jako téma MeSH
- morbidita MeSH
- mortalita MeSH
- nutriční nároky MeSH
- parenterální výživa MeSH
- pozorovací studie jako téma MeSH
- randomizované kontrolované studie jako téma MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
The guidelines for nutritional support in critically ill adult patients differ in various aspects. The optimal amount of energy and nutritional substrates supplied is important for reducing morbidity and mortality, but unfortunately this is not well known, because the topic is complex and every patient is individual. The aim of this review was to gather recent pertinent information concerning the nutritional support of critically ill patients in the intensive care unit (ICU) with respect to the energy, protein, carbohydrate, and lipid intakes and the effect of their specific utilization on morbidity and mortality. Enteral nutrition (EN) is generally recommended over parenteral nutrition (PN) and is beneficial when administered within 24-48 h after ICU admission. In contrast, early PN does not provide substantial advantages in terms of morbidity and mortality, and the time when it is safe and beneficial remains unclear. The most advantageous recommendation seems to be administration of a hypocaloric (<20 kcal · kg-1 · d-1), high-protein diet (amino acids at doses of ≥2 g · kg-1 · d-1), at least during the first week of critical illness. Another important factor for reducing morbidity is the maintenance of blood glucose concentrations at 120-150 mg/dL, which is accomplished with the use of insulin and lower doses of glucose of 1-2 g · kg-1 · d-1, because this prevents the risk of hypoglycemia and is associated with a better prognosis according to recent studies. A fat emulsion is used as a source of required calories because of insulin resistance in the majority of patients. In addition, lipid oxidation in these patients is ∼25% higher than in healthy subjects.
Departments of Biological and Medical Sciences and Departments of Research and Development and
Departments of Research and Development and
Surgery University Hospital Hradec Kralove Hradec Kralove Czech Republic
Citace poskytuje Crossref.org
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