-
Je něco špatně v tomto záznamu ?
Subjective Cognitive Complaints in Cognitively Healthy Older Adults and Their Relationship to Cognitive Performance and Depressive Symptoms
H. Markova, R. Andel, H. Stepankova, M. Kopecek, T. Nikolai, J. Hort, C. Thomas-Antérion, M. Vyhnalek,
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články
Grantová podpora
NV16-27611A
MZ0
CEP - Centrální evidence projektů
PubMed
28697555
DOI
10.3233/jad-160970
Knihovny.cz E-zdroje
- MeSH
- deprese epidemiologie patofyziologie psychologie MeSH
- kognitivní poruchy epidemiologie patofyziologie psychologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- longitudinální studie MeSH
- neuropsychologické testy MeSH
- osobnost MeSH
- průzkumy a dotazníky MeSH
- samostatný způsob života MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- stárnutí psychologie MeSH
- záznam o duševním stavu MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
BACKGROUND: Subjective cognitive complaints (SCCs) may be an early marker of prodromal Alzheimer's disease. OBJECTIVES: Using a 10-item yes/no SCCs questionnaire (Le Questionnaire de Plainte Cognitive [QPC]), we evaluated the prevalence and distribution of SCCs in cognitively healthy Czech older adults and examined total score and specific QPC items in relation to depressive symptomology and cognitive performance. METHODS: A sample of 340 cognitively healthy older community-dwelling volunteers aged 60 or older from the third wave of the longitudinal project National Normative Study of Cognitive Determinants of Healthy Aging, who underwent a comprehensive neuropsychological assessment and completed the QPC and the 15-item Geriatric Depression Scale (GDS-15). Regression analysis was controlled for age when GDS-15 was the outcome and for age and GDS-15 with cognitive domains as the outcome. RESULTS: 71% reported 1 + SCCs, with prevalence of individual complaints ranging from 4% to 40%. The number of SCCs was associated with GDS-15 (p < 0.001). Personality change (p < 0.001) and Limitation in daily activities (p = 0.002) were significantly associated with higher GDS-15 score and Spatial orientation difficulties (p = 0.019) and Impression of worse memory in comparison to peers (p = 0.012) were significantly associated with lower memory performance. CONCLUSIONS: We identified some cognitive complaints that were very common in our sample. Overall, a higher number of SCCs in well cognitively functioning individuals was most closely related to depressive symptomatology, while some specific complaints reflected lower memory performance and should be considered when screening for people at risk of cognitive decline.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc18024850
- 003
- CZ-PrNML
- 005
- 20180713111939.0
- 007
- ta
- 008
- 180709s2017 ne f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.3233/JAD-160970 $2 doi
- 035 __
- $a (PubMed)28697555
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a ne
- 100 1_
- $a Markova, Hana $u Department of Neurology, Memory Clinic, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic. International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.
- 245 10
- $a Subjective Cognitive Complaints in Cognitively Healthy Older Adults and Their Relationship to Cognitive Performance and Depressive Symptoms / $c H. Markova, R. Andel, H. Stepankova, M. Kopecek, T. Nikolai, J. Hort, C. Thomas-Antérion, M. Vyhnalek,
- 520 9_
- $a BACKGROUND: Subjective cognitive complaints (SCCs) may be an early marker of prodromal Alzheimer's disease. OBJECTIVES: Using a 10-item yes/no SCCs questionnaire (Le Questionnaire de Plainte Cognitive [QPC]), we evaluated the prevalence and distribution of SCCs in cognitively healthy Czech older adults and examined total score and specific QPC items in relation to depressive symptomology and cognitive performance. METHODS: A sample of 340 cognitively healthy older community-dwelling volunteers aged 60 or older from the third wave of the longitudinal project National Normative Study of Cognitive Determinants of Healthy Aging, who underwent a comprehensive neuropsychological assessment and completed the QPC and the 15-item Geriatric Depression Scale (GDS-15). Regression analysis was controlled for age when GDS-15 was the outcome and for age and GDS-15 with cognitive domains as the outcome. RESULTS: 71% reported 1 + SCCs, with prevalence of individual complaints ranging from 4% to 40%. The number of SCCs was associated with GDS-15 (p < 0.001). Personality change (p < 0.001) and Limitation in daily activities (p = 0.002) were significantly associated with higher GDS-15 score and Spatial orientation difficulties (p = 0.019) and Impression of worse memory in comparison to peers (p = 0.012) were significantly associated with lower memory performance. CONCLUSIONS: We identified some cognitive complaints that were very common in our sample. Overall, a higher number of SCCs in well cognitively functioning individuals was most closely related to depressive symptomatology, while some specific complaints reflected lower memory performance and should be considered when screening for people at risk of cognitive decline.
- 650 _2
- $a senioři $7 D000368
- 650 _2
- $a senioři nad 80 let $7 D000369
- 650 _2
- $a stárnutí $x psychologie $7 D000375
- 650 _2
- $a kognitivní poruchy $x epidemiologie $x patofyziologie $x psychologie $7 D003072
- 650 _2
- $a deprese $x epidemiologie $x patofyziologie $x psychologie $7 D003863
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a samostatný způsob života $7 D057187
- 650 _2
- $a longitudinální studie $7 D008137
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a záznam o duševním stavu $7 D008609
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a neuropsychologické testy $7 D009483
- 650 _2
- $a osobnost $7 D010551
- 650 _2
- $a průzkumy a dotazníky $7 D011795
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Andel, Ross $u International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic. School of Aging Studies, University of South Florida, Tampa, FL, USA.
- 700 1_
- $a Stepankova, Hana $u National Institute of Mental Health, Klecany, Czech Republic.
- 700 1_
- $a Kopecek, Miloslav $u National Institute of Mental Health, Klecany, Czech Republic.
- 700 1_
- $a Nikolai, Tomas $u Department of Neurology, Memory Clinic, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic. International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic. National Institute of Mental Health, Klecany, Czech Republic.
- 700 1_
- $a Hort, Jakub $u Department of Neurology, Memory Clinic, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic. International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.
- 700 1_
- $a Thomas-Antérion, Catherine $u Laboratoire de sciences cognitives, Université Lyon 2, France.
- 700 1_
- $a Vyhnalek, Martin $u Department of Neurology, Memory Clinic, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic. International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.
- 773 0_
- $w MED00006350 $t Journal of Alzheimer's disease JAD $x 1875-8908 $g Roč. 59, č. 3 (2017), s. 871-881
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/28697555 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20180709 $b ABA008
- 991 __
- $a 20180713112233 $b ABA008
- 999 __
- $a ok $b bmc $g 1316981 $s 1021771
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2017 $b 59 $c 3 $d 871-881 $i 1875-8908 $m Journal of Alzheimer's disease $n J Alzheimers Dis $x MED00006350
- GRA __
- $a NV16-27611A $p MZ0
- LZP __
- $a Pubmed-20180709
